108 related articles for article (PubMed ID: 21275050)
21. Structure-based design, synthesis, and biological evaluation of inhibitors of Mycobacterium tuberculosis type II dehydroquinase.
Sánchez-Sixto C; Prazeres VF; Castedo L; Lamb H; Hawkins AR; González-Bello C
J Med Chem; 2005 Jul; 48(15):4871-81. PubMed ID: 16033267
[TBL] [Abstract][Full Text] [Related]
22. Inhibition of Shikimate Kinase and Type II Dehydroquinase for Antibiotic Discovery: Structure-Based Design and Simulation Studies.
Gonzalez-Bello C
Curr Top Med Chem; 2016; 16(9):960-77. PubMed ID: 26303426
[TBL] [Abstract][Full Text] [Related]
23. Bicyclic and tricyclic thiophenes as protein tyrosine phosphatase 1B inhibitors.
Moretto AF; Kirincich SJ; Xu WX; Smith MJ; Wan ZK; Wilson DP; Follows BC; Binnun E; Joseph-McCarthy D; Foreman K; Erbe DV; Zhang YL; Tam SK; Tam SY; Lee J
Bioorg Med Chem; 2006 Apr; 14(7):2162-77. PubMed ID: 16303309
[TBL] [Abstract][Full Text] [Related]
24. An antibacterial thiophene from Balsamorhiza sagittata.
Matsuura H; Saxena G; Farmer SW; Hancock RE; Towers GH
Planta Med; 1996 Feb; 62(1):65-6. PubMed ID: 8720391
[TBL] [Abstract][Full Text] [Related]
25. Synthesis and evaluation of benzo[b]thiophene derivatives as inhibitors of alkaline phosphatases.
Li L; Chang L; Pellet-Rostaing S; Liger F; Lemaire M; Buchet R; Wu Y
Bioorg Med Chem; 2009 Oct; 17(20):7290-300. PubMed ID: 19781951
[TBL] [Abstract][Full Text] [Related]
26. Exploring the water-binding pocket of the type II dehydroquinase enzyme in the structure-based design of inhibitors.
Blanco B; Sedes A; Peón A; Otero JM; van Raaij MJ; Thompson P; Hawkins AR; González-Bello C
J Med Chem; 2014 Apr; 57(8):3494-510. PubMed ID: 24689821
[TBL] [Abstract][Full Text] [Related]
27. Regulation of human carbonic anhydrase I (hCAI) activity by using a photochromic inhibitor.
Vomasta D; Högner C; Branda NR; König B
Angew Chem Int Ed Engl; 2008; 47(40):7644-7. PubMed ID: 18767093
[No Abstract] [Full Text] [Related]
28. Mechanistic basis of the inhibition of type II dehydroquinase by (2S)- and (2R)-2-benzyl-3-dehydroquinic acids.
Lence E; Tizón L; Otero JM; Peón A; Prazeres VF; Llamas-Saiz AL; Fox GC; van Raaij MJ; Lamb H; Hawkins AR; González-Bello C
ACS Chem Biol; 2013 Mar; 8(3):568-77. PubMed ID: 23198883
[TBL] [Abstract][Full Text] [Related]
29. Parallel solid-phase synthesis and evaluation of inhibitors of Streptomyces coelicolor type II dehydroquinase.
González-Bello C; Lence E; Toscano MD; Castedo L; Coggins JR; Abell C
J Med Chem; 2003 Dec; 46(26):5735-44. PubMed ID: 14667226
[TBL] [Abstract][Full Text] [Related]
30. Identification of novel inhibitors of bacterial surface enzyme Staphylococcus aureus Sortase A.
Chenna BC; Shinkre BA; King JR; Lucius AL; Narayana SV; Velu SE
Bioorg Med Chem Lett; 2008 Jan; 18(1):380-5. PubMed ID: 18023345
[TBL] [Abstract][Full Text] [Related]
31. Design and synthesis of quinolinones as methionyl-tRNA synthetase inhibitors.
Farhanullah ; Kim SY; Yoon EJ; Choi EC; Kim S; Kang T; Samrin F; Puri S; Lee J
Bioorg Med Chem; 2006 Nov; 14(21):7154-9. PubMed ID: 16854585
[TBL] [Abstract][Full Text] [Related]
32. Heterocyclic inhibitors of dihydrodipicolinate synthase are not competitive.
Turner JJ; Gerrard JA; Hutton CA
Bioorg Med Chem; 2005 Mar; 13(6):2133-40. PubMed ID: 15727866
[TBL] [Abstract][Full Text] [Related]
33. Novel pyrazole derivatives as potent inhibitors of type II topoisomerases. Part 1: synthesis and preliminary SAR analysis.
Gomez L; Hack MD; Wu J; Wiener JJ; Venkatesan H; Santillán A; Pippel DJ; Mani N; Morrow BJ; Motley ST; Shaw KJ; Wolin R; Grice CA; Jones TK
Bioorg Med Chem Lett; 2007 May; 17(10):2723-7. PubMed ID: 17368897
[TBL] [Abstract][Full Text] [Related]
34. Crystal structure of the type II 3-dehydroquinase from Helicobacter pylori.
Lee BI; Kwak JE; Suh SW
Proteins; 2003 Jun; 51(4):616-7. PubMed ID: 12784220
[No Abstract] [Full Text] [Related]
35. Reducing the Flexibility of Type II Dehydroquinase for Inhibition: A Fragment-Based Approach and Molecular Dynamics Study.
Peón A; Robles A; Blanco B; Convertino M; Thompson P; Hawkins AR; Caflisch A; González-Bello C
ChemMedChem; 2017 Sep; 12(18):1512-1524. PubMed ID: 28791799
[TBL] [Abstract][Full Text] [Related]
36. 4,5-Disubstituted cis-pyrrolidinones as inhibitors of type II 17beta-hydroxysteroid dehydrogenase. Part 3. Identification of lead candidate.
Wood J; Bagi CM; Akuche C; Bacchiocchi A; Baryza J; Blue ML; Brennan C; Campbell AM; Choi S; Cook JH; Conrad P; Dixon BR; Ehrlich PP; Gane T; Gunn D; Joe T; Johnson JS; Jordan J; Kramss R; Liu P; Levy J; Lowe DB; McAlexander I; Natero R; Redman AM; Scott WJ; Town C; Wang M; Wang Y; Zhang Z
Bioorg Med Chem Lett; 2006 Sep; 16(18):4965-8. PubMed ID: 16806919
[TBL] [Abstract][Full Text] [Related]
37. Two new irreversible inhibitors of dihydrodipicolinate synthase: diethyl (E,E)-4-oxo-2,5-heptadienedioate and diethyl (E)-4-oxo-2-heptenedioate.
Turner JJ; Healy JP; Dobson RC; Gerrard JA; Hutton CA
Bioorg Med Chem Lett; 2005 Feb; 15(4):995-8. PubMed ID: 15686899
[TBL] [Abstract][Full Text] [Related]
38. A study on conformationally restricted sangivamycins and their inhibitory abilities of protein kinases.
Iimori T; Murai Y; Sugiyama T; Shiroto H; Ishizaki T; Wakizaka Y; Kodama Y; Ohuchi S; Ohtsuka Y; Oishi T
Nucleic Acids Symp Ser; 1992; (27):169-70. PubMed ID: 1289806
[TBL] [Abstract][Full Text] [Related]
39. Complexes of 2-thiophenecarbonyl and isonicotinoyl hydrazones of 3-(N-methyl)isatin. A study of their antimicrobial activity.
Rodríguez-Argüelles MC; Mosquera-Vázquez S; Tourón-Touceda P; Sanmartín-Matalobos J; García-Deibe AM; Belicchi-Ferrari M; Pelosi G; Pelizzi C; Zani F
J Inorg Biochem; 2007 Jan; 101(1):138-47. PubMed ID: 17070919
[TBL] [Abstract][Full Text] [Related]
40. Discovery of a new class of protein farnesyltransferase inhibitors in the arylthiophene series.
Lethu S; Ginisty M; Bosc D; Dubois J
J Med Chem; 2009 Oct; 52(20):6205-8. PubMed ID: 19772293
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]