107 related articles for article (PubMed ID: 21277202)
1. Synthesis of GN8 derivatives and evaluation of their antiprion activity in TSE-infected cells.
Kimura T; Hosokawa-Muto J; Kamatari YO; Kuwata K
Bioorg Med Chem Lett; 2011 Mar; 21(5):1502-7. PubMed ID: 21277202
[TBL] [Abstract][Full Text] [Related]
2. Similar structure-activity relationships of quinoline derivatives for antiprion and antimalarial effects.
Klingenstein R; Melnyk P; Leliveld SR; Ryckebusch A; Korth C
J Med Chem; 2006 Aug; 49(17):5300-8. PubMed ID: 16913719
[TBL] [Abstract][Full Text] [Related]
3. Synthesis of benzamide derivatives and their evaluation as antiprion agents.
Fiorino F; Eiden M; Giese A; Severino B; Esposito A; Groschup MH; Perissutti E; Magli E; Incisivo GM; Ciano A; Frecentese F; Kretzschmar HA; Wagner J; Santagada V; Caliendo G
Bioorg Med Chem; 2012 Aug; 20(16):5001-11. PubMed ID: 22795751
[TBL] [Abstract][Full Text] [Related]
4. Prion inhibition with multivalent PrPSc binding compounds.
Mays CE; Joy S; Li L; Yu L; Genovesi S; West FG; Westaway D
Biomaterials; 2012 Oct; 33(28):6808-22. PubMed ID: 22748770
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis, and biological evaluation of bromophenol derivatives as protein tyrosine phosphatase 1B inhibitors.
Jiang B; Shi D; Cui Y; Guo S
Arch Pharm (Weinheim); 2012 Jun; 345(6):444-53. PubMed ID: 22307562
[TBL] [Abstract][Full Text] [Related]
6. Structure-activity relationship refinement and further assessment of indole-3-glyoxylamides as a lead series against prion disease.
Thompson MJ; Louth JC; Ferrara S; Sorrell FJ; Irving BJ; Cochrane EJ; Meijer AJ; Chen B
ChemMedChem; 2011 Jan; 6(1):115-30. PubMed ID: 21154498
[TBL] [Abstract][Full Text] [Related]
7. Antiprion activity of functionalized 9-aminoacridines related to quinacrine.
Nguyen TH; Lee CY; Teruya K; Ong WY; Doh-ura K; Go ML
Bioorg Med Chem; 2008 Jul; 16(14):6737-46. PubMed ID: 18556207
[TBL] [Abstract][Full Text] [Related]
8. Discovery of diphenylmethane analogs as anti-bovine diarrhea viral agents.
Hosoda S; Aoyama H; Goto Y; Salim MT; Okamoto M; Hashimoto M; Baba M; Hashimoto Y
Bioorg Med Chem Lett; 2009 Jun; 19(12):3157-61. PubMed ID: 19447037
[TBL] [Abstract][Full Text] [Related]
9. Further structural exploration of trisubstituted asymmetric pyran derivatives (2S,4R,5R)-2-benzhydryl-5-benzylamino-tetrahydropyran-4-ol and their corresponding disubstituted (3S,6S) pyran derivatives: a proposed pharmacophore model for high-affinity interaction with the dopamine, serotonin, and norepinephrine transporters.
Zhang S; Fernandez F; Hazeldine S; Deschamps J; Zhen J; Reith ME; Dutta AK
J Med Chem; 2006 Jul; 49(14):4239-47. PubMed ID: 16821783
[TBL] [Abstract][Full Text] [Related]
10. Novel N-phenyl dichloroacetamide derivatives as anticancer reagents: design, synthesis and biological evaluation.
Yang Y; Shang P; Cheng C; Wang D; Yang P; Zhang F; Li T; Lu A; Zhao Y
Eur J Med Chem; 2010 Sep; 45(9):4300-6. PubMed ID: 20663593
[TBL] [Abstract][Full Text] [Related]
11. Discovery of a class of diketopiperazines as antiprion compounds.
Bolognesi ML; Ai Tran HN; Staderini M; Monaco A; López-Cobeñas A; Bongarzone S; Biarnés X; López-Alvarado P; Cabezas N; Caramelli M; Carloni P; Menéndez JC; Legname G
ChemMedChem; 2010 Aug; 5(8):1324-34. PubMed ID: 20540064
[TBL] [Abstract][Full Text] [Related]
12. Structural insight into the antiprion compound inhibition mechanism of native prion folding over misfolding.
Choi J; Govindaraj RG; Hyeon JW; Lee K; Ma S; Kim SY; Lee J; No KT
Chem Biol Drug Des; 2017 Jun; 89(6):907-917. PubMed ID: 27933736
[TBL] [Abstract][Full Text] [Related]
13. [Beclobrate and eniclobrate hydrochloride, new diphenylmethane derivatives as agents for lowering cholesterol and triglyceride levels. Part I: Synthesis and consideration of structure-activity relationships (author's transl)].
Thiele K; Ahmed Q; Jahn U; Adrian RW
Arzneimittelforschung; 1979; 29(5):711-20. PubMed ID: 582967
[TBL] [Abstract][Full Text] [Related]
14. Discovery of benzhydrylpiperazine derivatives as CB1 receptor inverse agonists via privileged structure-based approach.
Meng T; Wang J; Peng H; Fang G; Li M; Xiong B; Xie X; Zhang Y; Wang X; Shen J
Eur J Med Chem; 2010 Mar; 45(3):1133-9. PubMed ID: 20047779
[TBL] [Abstract][Full Text] [Related]
15. Structure-activity relationships of diphenylpiperazine N-type calcium channel inhibitors.
Pajouhesh H; Feng ZP; Ding Y; Zhang L; Pajouhesh H; Morrison JL; Belardetti F; Tringham E; Simonson E; Vanderah TW; Porreca F; Zamponi GW; Mitscher LA; Snutch TP
Bioorg Med Chem Lett; 2010 Feb; 20(4):1378-83. PubMed ID: 20117000
[TBL] [Abstract][Full Text] [Related]
16. Benzoylurea derivatives as a novel class of antimitotic agents: synthesis, anticancer activity, and structure-activity relationships.
Song DQ; Wang Y; Wu LZ; Yang P; Wang YM; Gao LM; Li Y; Qu JR; Wang YH; Li YH; Du NN; Han YX; Zhang ZP; Jiang JD
J Med Chem; 2008 Jun; 51(11):3094-103. PubMed ID: 18457382
[TBL] [Abstract][Full Text] [Related]
17. Evaluation of the antiprion activity of 6-aminophenanthridines and related heterocycles.
Nguyen P; Oumata N; Soubigou F; Evrard J; Desban N; Lemoine P; Bouaziz S; Blondel M; Voisset C
Eur J Med Chem; 2014 Jul; 82():363-71. PubMed ID: 24927056
[TBL] [Abstract][Full Text] [Related]
18. Discovery of novel trisubstituted asymmetric derivatives of (2S,4R,5R)-2-benzhydryl-5-benzylaminotetrahydropyran-4-ol, exhibiting high affinity for serotonin and norepinephrine transporters in a stereospecific manner.
Zhang S; Zhen J; Reith ME; Dutta AK
J Med Chem; 2005 Jul; 48(15):4962-71. PubMed ID: 16033275
[TBL] [Abstract][Full Text] [Related]
19. High affinity hydroxypiperidine analogues of 4-(2-benzhydryloxyethyl)-1-(4-fluorobenzyl)piperidine for the dopamine transporter: stereospecific interactions in vitro and in vivo.
Ghorai SK; Cook C; Davis M; Venkataraman SK; George C; Beardsley PM; Reith ME; Dutta AK
J Med Chem; 2003 Mar; 46(7):1220-8. PubMed ID: 12646032
[TBL] [Abstract][Full Text] [Related]
20. Tricyclic antidepressants, quinacrine and a novel, synthetic chimera thereof clear prions by destabilizing detergent-resistant membrane compartments.
Klingenstein R; Löber S; Kujala P; Godsave S; Leliveld SR; Gmeiner P; Peters PJ; Korth C
J Neurochem; 2006 Aug; 98(3):748-59. PubMed ID: 16749906
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
