BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

421 related articles for article (PubMed ID: 21277363)

  • 41. The human hepatic metabolism of simvastatin hydroxy acid is mediated primarily by CYP3A, and not CYP2D6.
    Prueksaritanont T; Ma B; Yu N
    Br J Clin Pharmacol; 2003 Jul; 56(1):120-4. PubMed ID: 12848784
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Characterisation of cytochrome P450 isoenzyme activity in sheep liver and placental microsomes.
    Meakin AS; Amirmostofian M; Darby JR; Holman SL; Morrison JL; Wiese MD
    Placenta; 2023 Jan; 131():82-89. PubMed ID: 36527743
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Cytochrome P-450 3A4 and 2C8 are involved in zopiclone metabolism.
    Becquemont L; Mouajjah S; Escaffre O; Beaune P; Funck-Brentano C; Jaillon P
    Drug Metab Dispos; 1999 Sep; 27(9):1068-73. PubMed ID: 10460808
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Cytochrome P450 reaction phenotyping and inhibition and induction studies of pinostrobin in human liver microsomes and hepatocytes.
    Tan S; Dong Z; Zhang J; Efferth T; Fu Y; Hua X
    Biomed Chromatogr; 2017 Jun; 31(6):. PubMed ID: 28111763
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Hydroxylation and demethylation of the tricyclic antidepressant nortriptyline by cDNA-expressed human cytochrome P-450 isozymes.
    Olesen OV; Linnet K
    Drug Metab Dispos; 1997 Jun; 25(6):740-4. PubMed ID: 9193876
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Oxidative metabolism of koumine is mainly catalyzed by microsomal CYP3A4/3A5.
    Hu Y; Wang Z; Huang X; Xia B; Tang L; Zheng Z; Ye L
    Xenobiotica; 2017 Jul; 47(7):584-591. PubMed ID: 27499416
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Cytochrome P450 3A-mediated metabolism of buspirone in human liver microsomes.
    Zhu M; Zhao W; Jimenez H; Zhang D; Yeola S; Dai R; Vachharajani N; Mitroka J
    Drug Metab Dispos; 2005 Apr; 33(4):500-7. PubMed ID: 15640381
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Stereoselective metabolism of cibenzoline, an antiarrhythmic drug, by human and rat liver microsomes: possible involvement of CYP2D and CYP3A.
    Niwa T; Shiraga T; Mitani Y; Terakawa M; Tokuma Y; Kagayama A
    Drug Metab Dispos; 2000 Sep; 28(9):1128-34. PubMed ID: 10950860
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Inhibitory effects of gypenosides on seven human cytochrome P450 enzymes in vitro.
    He M; Jiang J; Qiu F; Liu S; Peng P; Gao C; Miao P
    Food Chem Toxicol; 2013 Jul; 57():262-5. PubMed ID: 23583485
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Identification of CYP3A4 as the primary cytochrome P450 responsible for the metabolism of tandospirone by human liver microsomes.
    Natsui K; Mizuno Y; Tani N; Yabuki M; Komuro S
    Eur J Drug Metab Pharmacokinet; 2007; 32(4):233-40. PubMed ID: 18348473
    [TBL] [Abstract][Full Text] [Related]  

  • 51. [Metabolites and metabolic pathways of mesaconitine in rat liver microsomal investigated by using UPLC-MS/MS method in vitro].
    Bi YF; Liu S; Zhang RX; Song FR; Liu ZQ
    Yao Xue Xue Bao; 2013 Dec; 48(12):1823-8. PubMed ID: 24689241
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Studies on metabolites and metabolic pathways of bulleyaconitine A in rat liver microsomes using LC-MS(n) combined with specific inhibitors.
    Bi Y; Zhuang X; Zhu H; Song F; Liu Z; Liu S
    Biomed Chromatogr; 2015 Jul; 29(7):1027-34. PubMed ID: 25425064
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Metabolism of carteolol by cDNA-expressed human cytochrome P450.
    Kudo S; Uchida M; Odomi M
    Eur J Clin Pharmacol; 1997; 52(6):479-85. PubMed ID: 9342584
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Identification of human cytochrome P450 isozymes involved in the metabolism of naftopidil enantiomers in vitro.
    Zhu L; Liu X; Zhu L; Zhang X; Fu X; Huang J; Yuan M
    J Pharm Pharmacol; 2014 Nov; 66(11):1534-51. PubMed ID: 24944083
    [TBL] [Abstract][Full Text] [Related]  

  • 55. In vitro metabolism of quinidine: the (3S)-3-hydroxylation of quinidine is a specific marker reaction for cytochrome P-4503A4 activity in human liver microsomes.
    Nielsen TL; Rasmussen BB; Flinois JP; Beaune P; Brosen K
    J Pharmacol Exp Ther; 1999 Apr; 289(1):31-7. PubMed ID: 10086984
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Characterization of human cytochrome P450 isoenzymes involved in the metabolism of vinorelbine.
    Beulz-Riché D; Grudé P; Puozzo C; Sautel F; Filaquier C; Riché C; Ratanasavanh D
    Fundam Clin Pharmacol; 2005 Oct; 19(5):545-53. PubMed ID: 16176333
    [TBL] [Abstract][Full Text] [Related]  

  • 57. O- and N-demethylation of venlafaxine in vitro by human liver microsomes and by microsomes from cDNA-transfected cells: effect of metabolic inhibitors and SSRI antidepressants.
    Fogelman SM; Schmider J; Venkatakrishnan K; von Moltke LL; Harmatz JS; Shader RI; Greenblatt DJ
    Neuropsychopharmacology; 1999 May; 20(5):480-90. PubMed ID: 10192828
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Inhibitory effects of sanguinarine on human liver cytochrome P450 enzymes.
    Qi XY; Liang SC; Ge GB; Liu Y; Dong PP; Zhang JW; Wang AX; Hou J; Zhu LL; Yang L; Tu CX
    Food Chem Toxicol; 2013 Jun; 56():392-7. PubMed ID: 23500771
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Metabolism of novel anti-HIV agent 3-cyanomethyl-4-methyl-DCK by human liver microsomes and recombinant CYP enzymes.
    Zhuang XM; Deng JT; Li H; Kong WL; Ruan JX; Xie L
    Acta Pharmacol Sin; 2011 Oct; 32(10):1276-84. PubMed ID: 21970838
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Biotransformation of parathion in human liver: participation of CYP3A4 and its inactivation during microsomal parathion oxidation.
    Butler AM; Murray M
    J Pharmacol Exp Ther; 1997 Feb; 280(2):966-73. PubMed ID: 9023313
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 22.