BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

504 related articles for article (PubMed ID: 21278237)

  • 1. NRF2 blockade suppresses colon tumor angiogenesis by inhibiting hypoxia-induced activation of HIF-1α.
    Kim TH; Hur EG; Kang SJ; Kim JA; Thapa D; Lee YM; Ku SK; Jung Y; Kwak MK
    Cancer Res; 2011 Mar; 71(6):2260-75. PubMed ID: 21278237
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Knockdown of Nrf2 suppresses glioblastoma angiogenesis by inhibiting hypoxia-induced activation of HIF-1α.
    Ji X; Wang H; Zhu J; Zhu L; Pan H; Li W; Zhou Y; Cong Z; Yan F; Chen S
    Int J Cancer; 2014 Aug; 135(3):574-84. PubMed ID: 24374745
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Andrographolide inhibits hypoxia-induced HIF-1α-driven endothelin 1 secretion by activating Nrf2/HO-1 and promoting the expression of prolyl hydroxylases 2/3 in human endothelial cells.
    Lin HC; Su SL; Lu CY; Lin AH; Lin WC; Liu CS; Yang YC; Wang HM; Lii CK; Chen HW
    Environ Toxicol; 2017 Mar; 32(3):918-930. PubMed ID: 27297870
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Magnolol suppresses hypoxia-induced angiogenesis via inhibition of HIF-1α/VEGF signaling pathway in human bladder cancer cells.
    Chen MC; Lee CF; Huang WH; Chou TC
    Biochem Pharmacol; 2013 May; 85(9):1278-87. PubMed ID: 23416116
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The redox protein thioredoxin-1 (Trx-1) increases hypoxia-inducible factor 1alpha protein expression: Trx-1 overexpression results in increased vascular endothelial growth factor production and enhanced tumor angiogenesis.
    Welsh SJ; Bellamy WT; Briehl MM; Powis G
    Cancer Res; 2002 Sep; 62(17):5089-95. PubMed ID: 12208766
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Antiangiogenic activity of phthalides-enriched Angelica Sinensis extract by suppressing WSB-1/pVHL/HIF-1α/VEGF signaling in bladder cancer.
    Chen MC; Hsu WL; Chang WL; Chou TC
    Sci Rep; 2017 Jul; 7(1):5376. PubMed ID: 28710377
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of novel antiangiogenic anticancer activities of deguelin targeting hypoxia-inducible factor-1 alpha.
    Oh SH; Woo JK; Jin Q; Kang HJ; Jeong JW; Kim KW; Hong WK; Lee HY
    Int J Cancer; 2008 Jan; 122(1):5-14. PubMed ID: 17764071
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The DEK oncogene activates VEGF expression and promotes tumor angiogenesis and growth in HIF-1α-dependent and -independent manners.
    Zhang Y; Liu J; Wang S; Luo X; Li Y; Lv Z; Zhu J; Lin J; Ding L; Ye Q
    Oncotarget; 2016 Apr; 7(17):23740-56. PubMed ID: 26988756
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tanshinone IIA inhibits β-catenin/VEGF-mediated angiogenesis by targeting TGF-β1 in normoxic and HIF-1α in hypoxic microenvironments in human colorectal cancer.
    Sui H; Zhao J; Zhou L; Wen H; Deng W; Li C; Ji Q; Liu X; Feng Y; Chai N; Zhang Q; Cai J; Li Q
    Cancer Lett; 2017 Sep; 403():86-97. PubMed ID: 28602978
    [TBL] [Abstract][Full Text] [Related]  

  • 10. miR-148a inhibits early relapsed colorectal cancers and the secretion of VEGF by indirectly targeting HIF-1α under non-hypoxia/hypoxia conditions.
    Tsai HL; Miao ZF; Chen YT; Huang CW; Yeh YS; Yang IP; Wang JY
    J Cell Mol Med; 2019 May; 23(5):3572-3582. PubMed ID: 30834693
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Bone marrow-derived mesenchymal stem cells induced by inflammatory cytokines produce angiogenetic factors and promote prostate cancer growth.
    Yang KQ; Liu Y; Huang QH; Mo N; Zhang QY; Meng QG; Cheng JW
    BMC Cancer; 2017 Dec; 17(1):878. PubMed ID: 29268703
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Anti-tumor activity of the novel hexahydrocannabinol analog LYR-8 in Human colorectal tumor xenograft is mediated through the inhibition of Akt and hypoxia-inducible factor-1α activation.
    Thapa D; Kang Y; Park PH; Noh SK; Lee YR; Han SS; Ku SK; Jung Y; Kim JA
    Biol Pharm Bull; 2012; 35(6):924-32. PubMed ID: 22687485
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A hypoxia-dependent upregulation of hypoxia-inducible factor-1 by nuclear factor-κB promotes gastric tumour growth and angiogenesis.
    Nam SY; Ko YS; Jung J; Yoon J; Kim YH; Choi YJ; Park JW; Chang MS; Kim WH; Lee BL
    Br J Cancer; 2011 Jan; 104(1):166-74. PubMed ID: 21119667
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Imperatorin suppresses proliferation and angiogenesis of human colon cancer cell by targeting HIF-1α via the mTOR/p70S6K/4E-BP1 and MAPK pathways.
    Mi C; Ma J; Wang KS; Zuo HX; Wang Z; Li MY; Piao LX; Xu GH; Li X; Quan ZS; Jin X
    J Ethnopharmacol; 2017 May; 203():27-38. PubMed ID: 28341244
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular and functional evaluation of a novel HIF inhibitor, benzopyranyl 1,2,3-triazole compound.
    Park K; Lee HE; Lee SH; Lee D; Lee T; Lee YM
    Oncotarget; 2017 Jan; 8(5):7801-7813. PubMed ID: 27999195
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Antiangiogenic Potential of Microbial Metabolite Elaiophylin for Targeting Tumor Angiogenesis.
    Lim HN; Jang JP; Han JM; Jang JH; Ahn JS; Jung HJ
    Molecules; 2018 Mar; 23(3):. PubMed ID: 29498688
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effect of connective tissue growth factor on hypoxia-inducible factor 1alpha degradation and tumor angiogenesis.
    Chang CC; Lin MT; Lin BR; Jeng YM; Chen ST; Chu CY; Chen RJ; Chang KJ; Yang PC; Kuo ML
    J Natl Cancer Inst; 2006 Jul; 98(14):984-95. PubMed ID: 16849681
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel mechanism of action for hydralazine: induction of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and angiogenesis by inhibition of prolyl hydroxylases.
    Knowles HJ; Tian YM; Mole DR; Harris AL
    Circ Res; 2004 Jul; 95(2):162-9. PubMed ID: 15192023
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Jianpi Jiedu decoction, a traditional Chinese medicine formula, inhibits tumorigenesis, metastasis, and angiogenesis through the mTOR/HIF-1α/VEGF pathway.
    Peng W; Zhang S; Zhang Z; Xu P; Mao D; Huang S; Chen B; Zhang C; Zhang S
    J Ethnopharmacol; 2018 Oct; 224():140-148. PubMed ID: 29852266
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Antiangiogenic effects of a novel synthetic curcumin analogue in pancreatic cancer.
    Nagaraju GP; Zhu S; Ko JE; Ashritha N; Kandimalla R; Snyder JP; Shoji M; El-Rayes BF
    Cancer Lett; 2015 Feb; 357(2):557-65. PubMed ID: 25497868
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.