These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

422 related articles for article (PubMed ID: 21280052)

  • 1. Application of a high-throughput screening procedure with PEG-induced precipitation to compare relative protein solubility during formulation development with IgG1 monoclonal antibodies.
    Gibson TJ; Mccarty K; Mcfadyen IJ; Cash E; Dalmonte P; Hinds KD; Dinerman AA; Alvarez JC; Volkin DB
    J Pharm Sci; 2011 Mar; 100(3):1009-21. PubMed ID: 21280052
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A Micro-Polyethylene Glycol Precipitation Assay as a Relative Solubility Screening Tool for Monoclonal Antibody Design and Formulation Development.
    Toprani VM; Joshi SB; Kueltzo LA; Schwartz RM; Middaugh CR; Volkin DB
    J Pharm Sci; 2016 Aug; 105(8):2319-27. PubMed ID: 27368120
    [TBL] [Abstract][Full Text] [Related]  

  • 3. High-throughput screening techniques for rapid PEG-based precipitation of IgG4 mAb from clarified cell culture supernatant.
    Knevelman C; Davies J; Allen L; Titchener-Hooker NJ
    Biotechnol Prog; 2010; 26(3):697-705. PubMed ID: 20014099
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Predicting Colloidal Stability of High-Concentration Monoclonal Antibody Formulations in Common Pharmaceutical Buffers Using Improved Polyethylene Glycol Induced Protein Precipitation Assay.
    Meza NP; Hardy CA; Morin KH; Huang C; Raghava S; Song J; Zhang J; Wang Y
    Mol Pharm; 2023 Nov; 20(11):5842-5855. PubMed ID: 37867303
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Application of a PEG precipitation method for solubility screening: a tool for developing high protein concentration formulations.
    Li L; Kantor A; Warne N
    Protein Sci; 2013 Aug; 22(8):1118-23. PubMed ID: 23740802
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Limitations of polyethylene glycol-induced precipitation as predictive tool for protein solubility during formulation development.
    Hofmann M; Winzer M; Weber C; Gieseler H
    J Pharm Pharmacol; 2018 May; 70(5):648-654. PubMed ID: 28106257
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Development of a high-throughput solubility screening assay for use in antibody discovery.
    Chai Q; Shih J; Weldon C; Phan S; Jones BE
    MAbs; 2019; 11(4):747-756. PubMed ID: 30913963
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Purification of antibodies by precipitating impurities using Polyethylene Glycol to enable a two chromatography step process.
    Giese G; Myrold A; Gorrell J; Persson J
    J Chromatogr B Analyt Technol Biomed Life Sci; 2013 Nov; 938():14-21. PubMed ID: 24036248
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Viscosity of high concentration protein formulations of monoclonal antibodies of the IgG1 and IgG4 subclass - prediction of viscosity through protein-protein interaction measurements.
    Neergaard MS; Kalonia DS; Parshad H; Nielsen AD; Møller EH; van de Weert M
    Eur J Pharm Sci; 2013 Jun; 49(3):400-10. PubMed ID: 23624326
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Screening of monoclonal antibody formulations based on high-throughput thermostability and viscosity measurements: design of experiment and statistical analysis.
    He F; Woods CE; Trilisky E; Bower KM; Litowski JR; Kerwin BA; Becker GW; Narhi LO; Razinkov VI
    J Pharm Sci; 2011 Apr; 100(4):1330-40. PubMed ID: 24081468
    [TBL] [Abstract][Full Text] [Related]  

  • 11. High-throughput screening and stability optimization of anti-streptavidin IgG1 and IgG2 formulations.
    Alekseychyk L; Su C; Becker GW; Treuheit MJ; Razinkov VI
    J Biomol Screen; 2014 Oct; 19(9):1290-301. PubMed ID: 25023322
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Branched polyethylene glycol for protein precipitation.
    Sim SL; He T; Tscheliessnig A; Mueller M; Tan RB; Jungbauer A
    Biotechnol Bioeng; 2012 Mar; 109(3):736-46. PubMed ID: 22012585
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effects of Protein Conformation, Apparent Solubility, and Protein-Protein Interactions on the Rates and Mechanisms of Aggregation for an IgG1Monoclonal Antibody.
    Kalonia C; Toprani V; Toth R; Wahome N; Gabel I; Middaugh CR; Volkin DB
    J Phys Chem B; 2016 Jul; 120(29):7062-75. PubMed ID: 27380437
    [TBL] [Abstract][Full Text] [Related]  

  • 14. High throughput solubility and redissolution screening for antibody purification via combined PEG and zinc chloride precipitation.
    Gu Q; Li Z; Coffman JL; Przybycien TM; Zydney AL
    Biotechnol Prog; 2020 Nov; 36(6):e3041. PubMed ID: 32583625
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Solubility Challenges in High Concentration Monoclonal Antibody Formulations: Relationship with Amino Acid Sequence and Intermolecular Interactions.
    Pindrus M; Shire SJ; Kelley RF; Demeule B; Wong R; Xu Y; Yadav S
    Mol Pharm; 2015 Nov; 12(11):3896-907. PubMed ID: 26407030
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Formulation design and high-throughput excipient selection based on structural integrity and conformational stability of dilute and highly concentrated IgG1 monoclonal antibody solutions.
    Bhambhani A; Kissmann JM; Joshi SB; Volkin DB; Kashi RS; Middaugh CR
    J Pharm Sci; 2012 Mar; 101(3):1120-35. PubMed ID: 22147527
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Matching pH values for antibody stabilization and crystallization suggest rationale for accelerated development of biotherapeutic drugs.
    Sjuts H; Schreuder H; Engel CK; Bussemer T; Gokarn Y
    Drug Dev Res; 2020 May; 81(3):329-337. PubMed ID: 31758731
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The influence of covalently linked and free polyethylene glycol on the structural and release properties of rhBMP-2 loaded microspheres.
    Lochmann A; Nitzsche H; von Einem S; Schwarz E; Mäder K
    J Control Release; 2010 Oct; 147(1):92-100. PubMed ID: 20603166
    [TBL] [Abstract][Full Text] [Related]  

  • 19. High throughput thermostability screening of monoclonal antibody formulations.
    He F; Hogan S; Latypov RF; Narhi LO; Razinkov VI
    J Pharm Sci; 2010 Apr; 99(4):1707-20. PubMed ID: 19780136
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A high-throughput UPLC method for the characterization of chemical modifications in monoclonal antibody molecules.
    Stackhouse N; Miller AK; Gadgil HS
    J Pharm Sci; 2011 Dec; 100(12):5115-25. PubMed ID: 21789770
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.