These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

250 related articles for article (PubMed ID: 21285984)

  • 1. Targeted inhibition of mitochondrial Hsp90 suppresses localised and metastatic prostate cancer growth in a genetic mouse model of disease.
    Kang BH; Tavecchio M; Goel HL; Hsieh CC; Garlick DS; Raskett CM; Lian JB; Stein GS; Languino LR; Altieri DC
    Br J Cancer; 2011 Feb; 104(4):629-34. PubMed ID: 21285984
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Preclinical characterization of mitochondria-targeted small molecule hsp90 inhibitors, gamitrinibs, in advanced prostate cancer.
    Kang BH; Siegelin MD; Plescia J; Raskett CM; Garlick DS; Dohi T; Lian JB; Stein GS; Languino LR; Altieri DC
    Clin Cancer Res; 2010 Oct; 16(19):4779-88. PubMed ID: 20876793
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Feasibility and safety of targeting mitochondria for cancer therapy - preclinical characterization of gamitrinib, a first-in-class, mitochondriaL-targeted small molecule Hsp90 inhibitor.
    Hayat U; Elliott GT; Olszanski AJ; Altieri DC
    Cancer Biol Ther; 2022 Dec; 23(1):117-126. PubMed ID: 35129069
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cytoprotective mitochondrial chaperone TRAP-1 as a novel molecular target in localized and metastatic prostate cancer.
    Leav I; Plescia J; Goel HL; Li J; Jiang Z; Cohen RJ; Languino LR; Altieri DC
    Am J Pathol; 2010 Jan; 176(1):393-401. PubMed ID: 19948822
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Stage-specific inhibitory effects and associated mechanisms of silibinin on tumor progression and metastasis in transgenic adenocarcinoma of the mouse prostate model.
    Raina K; Rajamanickam S; Singh RP; Deep G; Chittezhath M; Agarwal R
    Cancer Res; 2008 Aug; 68(16):6822-30. PubMed ID: 18701508
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tumor Necrosis Factor Receptor-associated Protein 1 (TRAP1) Mutation and TRAP1 Inhibitor Gamitrinib-triphenylphosphonium (G-TPP) Induce a Forkhead Box O (FOXO)-dependent Cell Protective Signal from Mitochondria.
    Kim H; Yang J; Kim MJ; Choi S; Chung JR; Kim JM; Yoo YH; Chung J; Koh H
    J Biol Chem; 2016 Jan; 291(4):1841-1853. PubMed ID: 26631731
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 17-ABAG, a novel geldanamycin derivative, inhibits LNCaP-cell proliferation through heat shock protein 90 inhibition.
    Lin Z; Peng R; Li Z; Wang Y; Lu C; Shen Y; Wang J; Shi G
    Int J Mol Med; 2015 Aug; 36(2):424-32. PubMed ID: 26059743
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Murine prostate cancer inhibition by dietary phytochemicals--curcumin and phenyethylisothiocyanate.
    Barve A; Khor TO; Hao X; Keum YS; Yang CS; Reddy B; Kong AN
    Pharm Res; 2008 Sep; 25(9):2181-9. PubMed ID: 18437538
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Flavokawain A induces deNEDDylation and Skp2 degradation leading to inhibition of tumorigenesis and cancer progression in the TRAMP transgenic mouse model.
    Li X; Yokoyama NN; Zhang S; Ding L; Liu HM; Lilly MB; Mercola D; Zi X
    Oncotarget; 2015 Dec; 6(39):41809-24. PubMed ID: 26497688
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Combinatorial drug design targeting multiple cancer signaling networks controlled by mitochondrial Hsp90.
    Kang BH; Plescia J; Song HY; Meli M; Colombo G; Beebe K; Scroggins B; Neckers L; Altieri DC
    J Clin Invest; 2009 Mar; 119(3):454-64. PubMed ID: 19229106
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Efficacious chemoprevention of primary prostate cancer by flutamide in an autochthonous transgenic model.
    Raghow S; Kuliyev E; Steakley M; Greenberg N; Steiner MS
    Cancer Res; 2000 Aug; 60(15):4093-7. PubMed ID: 10945615
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Evidence for efficacy of new Hsp90 inhibitors revealed by ex vivo culture of human prostate tumors.
    Centenera MM; Gillis JL; Hanson AR; Jindal S; Taylor RA; Risbridger GP; Sutherland PD; Scher HI; Raj GV; Knudsen KE; Yeadon T; ; Tilley WD; Butler LM
    Clin Cancer Res; 2012 Jul; 18(13):3562-70. PubMed ID: 22573351
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Gene signatures distinguish stage-specific prostate cancer stem cells isolated from transgenic adenocarcinoma of the mouse prostate lesions and predict the malignancy of human tumors.
    Mazzoleni S; Jachetti E; Morosini S; Grioni M; Piras IS; Pala M; Bulfone A; Freschi M; Bellone M; Galli R
    Stem Cells Transl Med; 2013 Sep; 2(9):678-89. PubMed ID: 23884639
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A probasin-large T antigen transgenic mouse line develops prostate adenocarcinoma and neuroendocrine carcinoma with metastatic potential.
    Masumori N; Thomas TZ; Chaurand P; Case T; Paul M; Kasper S; Caprioli RM; Tsukamoto T; Shappell SB; Matusik RJ
    Cancer Res; 2001 Mar; 61(5):2239-49. PubMed ID: 11280793
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Targeting HSP90 attenuates angiotensin II-induced adventitial remodelling via suppression of mitochondrial fission.
    Huang G; Cong Z; Wang X; Yuan Y; Xu R; Lu Z; Wang X; Qi J
    Cardiovasc Res; 2020 Apr; 116(5):1071-1084. PubMed ID: 31346611
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regression of mouse prostatic intraepithelial neoplasia by nonsteroidal anti-inflammatory drugs in the transgenic adenocarcinoma mouse prostate model.
    Narayanan BA; Narayanan NK; Pittman B; Reddy BS
    Clin Cancer Res; 2004 Nov; 10(22):7727-37. PubMed ID: 15570007
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of the mitochondrial Hsp90 chaperone network: a novel, efficient treatment strategy for cancer?
    Siegelin MD
    Cancer Lett; 2013 Jun; 333(2):133-46. PubMed ID: 23376257
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sorafenib's inhibition of prostate cancer growth in transgenic adenocarcinoma mouse prostate mice and its differential effects on endothelial and pericyte growth during tumor angiogenesis.
    Bono AV; Pannellini T; Liberatore M; Montironi R; Cunico SC; Cheng L; Sasso F; Musiani P; Iezzi M
    Anal Quant Cytol Histol; 2010 Jun; 32(3):136-45. PubMed ID: 20701066
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Bitter melon extract impairs prostate cancer cell-cycle progression and delays prostatic intraepithelial neoplasia in TRAMP model.
    Ru P; Steele R; Nerurkar PV; Phillips N; Ray RB
    Cancer Prev Res (Phila); 2011 Dec; 4(12):2122-30. PubMed ID: 21911444
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Increased expression of MUC18 correlates with the metastatic progression of mouse prostate adenocarcinoma in the TRAMP model.
    Wu GJ; Fu P; Chiang CF; Huss WJ; Greenberg NM; Wu MW
    J Urol; 2005 May; 173(5):1778-83. PubMed ID: 15821586
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.