BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

148 related articles for article (PubMed ID: 21288305)

  • 1. Some binding-related drug properties are dependent on thermodynamic signature.
    Schön A; Madani N; Smith AB; Lalonde JM; Freire E
    Chem Biol Drug Des; 2011 Mar; 77(3):161-5. PubMed ID: 21288305
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Thermodynamics of binding of a low-molecular-weight CD4 mimetic to HIV-1 gp120.
    Schön A; Madani N; Klein JC; Hubicki A; Ng D; Yang X; Smith AB; Sodroski J; Freire E
    Biochemistry; 2006 Sep; 45(36):10973-80. PubMed ID: 16953583
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Crystal structures of HIV-1 gp120 envelope glycoprotein in complex with NBD analogues that target the CD4-binding site.
    Kwon YD; LaLonde JM; Yang Y; Elban MA; Sugawara A; Courter JR; Jones DM; Smith AB; Debnath AK; Kwong PD
    PLoS One; 2014; 9(1):e85940. PubMed ID: 24489681
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Binding thermodynamics of the N-terminal peptide of the CCR5 coreceptor to HIV-1 envelope glycoprotein gp120.
    Brower ET; Schön A; Klein JC; Freire E
    Biochemistry; 2009 Feb; 48(4):779-85. PubMed ID: 19170639
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Does Antibody Stabilize the Ligand Binding in GP120 of HIV-1 Envelope Protein? Evidence from MD Simulation.
    Yadav S; Pandey V; Kumar Tiwari R; Ojha RP; Dubey KD
    Molecules; 2021 Jan; 26(1):. PubMed ID: 33466381
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Palmitic acid analogs exhibit nanomolar binding affinity for the HIV-1 CD4 receptor and nanomolar inhibition of gp120-to-CD4 fusion.
    Paskaleva EE; Xue J; Lee DY; Shekhtman A; Canki M
    PLoS One; 2010 Aug; 5(8):e12168. PubMed ID: 20730055
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characterization of the multiple conformational States of free monomeric and trimeric human immunodeficiency virus envelope glycoproteins after fixation by cross-linker.
    Yuan W; Bazick J; Sodroski J
    J Virol; 2006 Jul; 80(14):6725-37. PubMed ID: 16809278
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Naturally occurring variability in the envelope glycoprotein of HIV-1 and development of cell entry inhibitors.
    Brower ET; Schön A; Freire E
    Biochemistry; 2010 Mar; 49(11):2359-67. PubMed ID: 20166763
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Enhanced dynamics of HIV gp120 glycoprotein by small molecule binding.
    Shrivastava I; LaLonde JM
    Biochemistry; 2011 May; 50(19):4173-83. PubMed ID: 21488663
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Energetics of the HIV gp120-CD4 binding reaction.
    Myszka DG; Sweet RW; Hensley P; Brigham-Burke M; Kwong PD; Hendrickson WA; Wyatt R; Sodroski J; Doyle ML
    Proc Natl Acad Sci U S A; 2000 Aug; 97(16):9026-31. PubMed ID: 10922058
    [TBL] [Abstract][Full Text] [Related]  

  • 11. CD4 mimics targeting the HIV entry mechanism and their hybrid molecules with a CXCR4 antagonist.
    Narumi T; Ochiai C; Yoshimura K; Harada S; Tanaka T; Nomura W; Arai H; Ozaki T; Ohashi N; Matsushita S; Tamamura H
    Bioorg Med Chem Lett; 2010 Oct; 20(19):5853-8. PubMed ID: 20728351
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Binding mode characterization of NBD series CD4-mimetic HIV-1 entry inhibitors by X-ray structure and resistance study.
    Curreli F; Kwon YD; Zhang H; Yang Y; Scacalossi D; Kwong PD; Debnath AK
    Antimicrob Agents Chemother; 2014 Sep; 58(9):5478-91. PubMed ID: 25001301
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Activation and Inactivation of Primary Human Immunodeficiency Virus Envelope Glycoprotein Trimers by CD4-Mimetic Compounds.
    Madani N; Princiotto AM; Zhao C; Jahanbakhshsefidi F; Mertens M; Herschhorn A; Melillo B; Smith AB; Sodroski J
    J Virol; 2017 Feb; 91(3):. PubMed ID: 27881646
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Local conformational stability of HIV-1 gp120 in unliganded and CD4-bound states as defined by amide hydrogen/deuterium exchange.
    Kong L; Huang CC; Coales SJ; Molnar KS; Skinner J; Hamuro Y; Kwong PD
    J Virol; 2010 Oct; 84(19):10311-21. PubMed ID: 20660185
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The C4 region as a target for HIV entry inhibitors--NMR mapping of the interacting segments of T20 and gp120.
    Moseri A; Biron Z; Arshava B; Scherf T; Naider F; Anglister J
    FEBS J; 2015 Dec; 282(24):4643-57. PubMed ID: 26432362
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular dynamics simulations reveal distinct differences in conformational dynamics and thermodynamics between the unliganded and CD4-bound states of HIV-1 gp120.
    Li Y; Deng L; Liang J; Dong GH; Xia YL; Fu YX; Liu SQ
    Phys Chem Chem Phys; 2020 Mar; 22(10):5548-5560. PubMed ID: 32119016
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Range of CD4-Bound Conformations of HIV-1 gp120, as Defined Using Conditional CD4-Induced Antibodies.
    Kaplan G; Roitburd-Berman A; Lewis GK; Gershoni JM
    J Virol; 2016 May; 90(9):4481-4493. PubMed ID: 26889042
    [TBL] [Abstract][Full Text] [Related]  

  • 18. HbAHP-25, an In-Silico Designed Peptide, Inhibits HIV-1 Entry by Blocking gp120 Binding to CD4 Receptor.
    Bashir T; Patgaonkar M; Kumar SC; Pasi A; Reddy KV
    PLoS One; 2015; 10(4):e0124839. PubMed ID: 25915507
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeting protein-protein interactions: a promising avenue of anti-HIV drug discovery.
    Zhan P; Li W; Chen H; Liu X
    Curr Med Chem; 2010; 17(29):3393-409. PubMed ID: 20712566
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Soluble CD4 and CD4-mimetic compounds inhibit HIV-1 infection by induction of a short-lived activated state.
    Haim H; Si Z; Madani N; Wang L; Courter JR; Princiotto A; Kassa A; DeGrace M; McGee-Estrada K; Mefford M; Gabuzda D; Smith AB; Sodroski J
    PLoS Pathog; 2009 Apr; 5(4):e1000360. PubMed ID: 19343205
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.