BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

344 related articles for article (PubMed ID: 21288574)

  • 1. p21 is dispensable for AID-mediated class switch recombination and mutagenesis of immunoglobulin genes during somatic hypermutation.
    Shansab M; Selsing E
    Mol Immunol; 2011 Mar; 48(6-7):973-8. PubMed ID: 21288574
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Apurinic/apyrimidinic endonuclease 1 (APE1) is dispensable for activation-induced cytidine deaminase (AID)-dependent somatic hypermutation in the immunoglobulin gene.
    Islam H; Kobayashi M; Honjo T
    Int Immunol; 2019 Jul; 31(8):543-554. PubMed ID: 30877298
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activation-induced deaminase (AID)-directed hypermutation in the immunoglobulin Smu region: implication of AID involvement in a common step of class switch recombination and somatic hypermutation.
    Nagaoka H; Muramatsu M; Yamamura N; Kinoshita K; Honjo T
    J Exp Med; 2002 Feb; 195(4):529-34. PubMed ID: 11854365
    [TBL] [Abstract][Full Text] [Related]  

  • 4. DNA targets of AID evolutionary link between antibody somatic hypermutation and class switch recombination.
    Hackney JA; Misaghi S; Senger K; Garris C; Sun Y; Lorenzo MN; Zarrin AA
    Adv Immunol; 2009; 101():163-89. PubMed ID: 19231595
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Separate domains of AID are required for somatic hypermutation and class-switch recombination.
    Shinkura R; Ito S; Begum NA; Nagaoka H; Muramatsu M; Kinoshita K; Sakakibara Y; Hijikata H; Honjo T
    Nat Immunol; 2004 Jul; 5(7):707-12. PubMed ID: 15195091
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The contested role of uracil DNA glycosylase in immunoglobulin gene diversification.
    Longerich S; Storb U
    Trends Genet; 2005 May; 21(5):253-6. PubMed ID: 15851057
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Negative regulation of activation-induced cytidine deaminase in B cells.
    Muto T; Okazaki IM; Yamada S; Tanaka Y; Kinoshita K; Muramatsu M; Nagaoka H; Honjo T
    Proc Natl Acad Sci U S A; 2006 Feb; 103(8):2752-7. PubMed ID: 16477013
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ubiquitylated PCNA plays a role in somatic hypermutation and class-switch recombination and is required for meiotic progression.
    Roa S; Avdievich E; Peled JU; Maccarthy T; Werling U; Kuang FL; Kan R; Zhao C; Bergman A; Cohen PE; Edelmann W; Scharff MD
    Proc Natl Acad Sci U S A; 2008 Oct; 105(42):16248-53. PubMed ID: 18854411
    [TBL] [Abstract][Full Text] [Related]  

  • 9. APE1 is dispensable for S-region cleavage but required for its repair in class switch recombination.
    Xu J; Husain A; Hu W; Honjo T; Kobayashi M
    Proc Natl Acad Sci U S A; 2014 Dec; 111(48):17242-7. PubMed ID: 25404348
    [TBL] [Abstract][Full Text] [Related]  

  • 10. DNA polymerases β and λ do not directly affect Ig variable region somatic hypermutation although their absence reduces the frequency of mutations.
    Schrader CE; Linehan EK; Ucher AJ; Bertocci B; Stavnezer J
    DNA Repair (Amst); 2013 Dec; 12(12):1087-93. PubMed ID: 24084171
    [TBL] [Abstract][Full Text] [Related]  

  • 11. AID targeting in antibody diversity.
    Pavri R; Nussenzweig MC
    Adv Immunol; 2011; 110():1-26. PubMed ID: 21762814
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Splicing regulator SRSF1-3 that controls somatic hypermutation of IgV genes interacts with topoisomerase 1 and AID.
    Kumar Singh A; Tamrakar A; Jaiswal A; Kanayama N; Agarwal A; Tripathi P; Kodgire P
    Mol Immunol; 2019 Dec; 116():63-72. PubMed ID: 31622795
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Transcription factor YY1 can control AID-mediated mutagenesis in mice.
    Zaprazna K; Basu A; Tom N; Jha V; Hodawadekar S; Radova L; Malcikova J; Tichy B; Pospisilova S; Atchison ML
    Eur J Immunol; 2018 Feb; 48(2):273-282. PubMed ID: 29080214
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Apex2 is required for efficient somatic hypermutation but not for class switch recombination of immunoglobulin genes.
    Sabouri Z; Okazaki IM; Shinkura R; Begum N; Nagaoka H; Tsuchimoto D; Nakabeppu Y; Honjo T
    Int Immunol; 2009 Aug; 21(8):947-55. PubMed ID: 19556307
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Activation-induced cytidine deaminase in antibody diversification and chromosome translocation.
    Gazumyan A; Bothmer A; Klein IA; Nussenzweig MC; McBride KM
    Adv Cancer Res; 2012; 113():167-90. PubMed ID: 22429855
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Bach2 regulates AID-mediated immunoglobulin gene conversion and somatic hypermutation in DT40 B cells.
    Budzyńska PM; Kyläniemi MK; Kallonen T; Soikkeli AI; Nera KP; Lassila O; Alinikula J
    Eur J Immunol; 2017 Jun; 47(6):993-1001. PubMed ID: 28301039
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Isotype-switched follicular lymphoma displays dissociation between activation-induced cytidine deaminase expression and somatic hypermutation.
    Scherer F; Navarrete MA; Bertinetti-Lapatki C; Boehm J; Schmitt-Graeff A; Veelken H
    Leuk Lymphoma; 2016; 57(1):151-60. PubMed ID: 25860234
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Lupus-prone MRL/faslpr/lpr mice display increased AID expression and extensive DNA lesions, comprising deletions and insertions, in the immunoglobulin locus: concurrent upregulation of somatic hypermutation and class switch DNA recombination.
    Zan H; Zhang J; Ardeshna S; Xu Z; Park SR; Casali P
    Autoimmunity; 2009 Feb; 42(2):89-103. PubMed ID: 19156553
    [TBL] [Abstract][Full Text] [Related]  

  • 19. AID preferentially targets the top strand in nucleosome sequences.
    Singh AK; Jaiswal A; Kodgire P
    Mol Immunol; 2019 Aug; 112():198-205. PubMed ID: 31176199
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DNA double strand breaks occur independent of AID in hypermutating Ig genes.
    Bross L; Jacobs H
    Clin Dev Immunol; 2003; 10(2-4):83-9. PubMed ID: 14768938
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.