BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

304 related articles for article (PubMed ID: 21289178)

  • 1. Disrupting function of FK506-binding protein 1b/12.6 induces the Ca²+-dysregulation aging phenotype in hippocampal neurons.
    Gant JC; Chen KC; Norris CM; Kadish I; Thibault O; Blalock EM; Porter NM; Landfield PW
    J Neurosci; 2011 Feb; 31(5):1693-703. PubMed ID: 21289178
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Reversal of Aging-Related Neuronal Ca2+ Dysregulation and Cognitive Impairment by Delivery of a Transgene Encoding FK506-Binding Protein 12.6/1b to the Hippocampus.
    Gant JC; Chen KC; Kadish I; Blalock EM; Thibault O; Porter NM; Landfield PW
    J Neurosci; 2015 Jul; 35(30):10878-87. PubMed ID: 26224869
    [TBL] [Abstract][Full Text] [Related]  

  • 3. FK506-binding protein 1b/12.6: a key to aging-related hippocampal Ca2+ dysregulation?
    Gant JC; Blalock EM; Chen KC; Kadish I; Porter NM; Norris CM; Thibault O; Landfield PW
    Eur J Pharmacol; 2014 Sep; 739():74-82. PubMed ID: 24291098
    [TBL] [Abstract][Full Text] [Related]  

  • 4. FK506-Binding Protein 12.6/1b, a Negative Regulator of [Ca
    Gant JC; Blalock EM; Chen KC; Kadish I; Thibault O; Porter NM; Landfield PW
    J Neurosci; 2018 Jan; 38(4):1030-1041. PubMed ID: 29255009
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Sensitized signalling between L-type Ca2+ channels and ryanodine receptors in the absence or inhibition of FKBP12.6 in cardiomyocytes.
    Zhao YT; Guo YB; Gu L; Fan XX; Yang HQ; Chen Z; Zhou P; Yuan Q; Ji GJ; Wang SQ
    Cardiovasc Res; 2017 Mar; 113(3):332-342. PubMed ID: 28077437
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Redox sensitive calcium stores underlie enhanced after hyperpolarization of aged neurons: role for ryanodine receptor mediated calcium signaling.
    Bodhinathan K; Kumar A; Foster TC
    J Neurophysiol; 2010 Nov; 104(5):2586-93. PubMed ID: 20884759
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Expansion of the calcium hypothesis of brain aging and Alzheimer's disease: minding the store.
    Thibault O; Gant JC; Landfield PW
    Aging Cell; 2007 Jun; 6(3):307-17. PubMed ID: 17465978
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Homeostatic and stimulus-induced coupling of the L-type Ca2+ channel to the ryanodine receptor in the hippocampal neuron in slices.
    Berrout J; Isokawa M
    Cell Calcium; 2009 Jul; 46(1):30-8. PubMed ID: 19411104
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Elevated postsynaptic [Ca2+]i and L-type calcium channel activity in aged hippocampal neurons: relationship to impaired synaptic plasticity.
    Thibault O; Hadley R; Landfield PW
    J Neurosci; 2001 Dec; 21(24):9744-56. PubMed ID: 11739583
    [TBL] [Abstract][Full Text] [Related]  

  • 10. FK506-binding protein (FKBP12) regulates ryanodine receptor-evoked Ca2+ release in colonic but not aortic smooth muscle.
    MacMillan D; Currie S; McCarron JG
    Cell Calcium; 2008 Jun; 43(6):539-49. PubMed ID: 17950843
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Regulation by FK506 and rapamycin of Ca2+ release from the sarcoplasmic reticulum in vascular smooth muscle: the role of FK506 binding proteins and mTOR.
    MacMillan D; McCarron JG
    Br J Pharmacol; 2009 Oct; 158(4):1112-20. PubMed ID: 19785652
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Chronic 1alpha,25-(OH)2 vitamin D3 treatment reduces Ca2+ -mediated hippocampal biomarkers of aging.
    Brewer LD; Porter NM; Kerr DS; Landfield PW; Thibault O
    Cell Calcium; 2006 Sep; 40(3):277-86. PubMed ID: 16780945
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hippocampal 'zipper' slice studies reveal a necessary role for calcineurin in the increased activity of L-type Ca(2+) channels with aging.
    Norris CM; Blalock EM; Chen KC; Porter NM; Thibault O; Kraner SD; Landfield PW
    Neurobiol Aging; 2010 Feb; 31(2):328-38. PubMed ID: 18471936
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Early and simultaneous emergence of multiple hippocampal biomarkers of aging is mediated by Ca2+-induced Ca2+ release.
    Gant JC; Sama MM; Landfield PW; Thibault O
    J Neurosci; 2006 Mar; 26(13):3482-90. PubMed ID: 16571755
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Age-related enhancement of the slow outward calcium-activated potassium current in hippocampal CA1 pyramidal neurons in vitro.
    Power JM; Wu WW; Sametsky E; Oh MM; Disterhoft JF
    J Neurosci; 2002 Aug; 22(16):7234-43. PubMed ID: 12177218
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Functional interaction of neuronal Cav1.3 L-type calcium channel with ryanodine receptor type 2 in the rat hippocampus.
    Kim S; Yun HM; Baik JH; Chung KC; Nah SY; Rhim H
    J Biol Chem; 2007 Nov; 282(45):32877-89. PubMed ID: 17823125
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Calcium-induced calcium release and type 3 ryanodine receptors modulate the slow afterhyperpolarising current, sIAHP, and its potentiation in hippocampal pyramidal neurons.
    Tedoldi A; Ludwig P; Fulgenzi G; Takeshima H; Pedarzani P; Stocker M
    PLoS One; 2020; 15(6):e0230465. PubMed ID: 32559219
    [TBL] [Abstract][Full Text] [Related]  

  • 18. RYR2 proteins contribute to the formation of Ca(2+) sparks in smooth muscle.
    Ji G; Feldman ME; Greene KS; Sorrentino V; Xin HB; Kotlikoff MI
    J Gen Physiol; 2004 Apr; 123(4):377-86. PubMed ID: 15024040
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The immunophilin FK506-binding protein modulates Ca2+ release channel closure in rat heart.
    Xiao RP; Valdivia HH; Bogdanov K; Valdivia C; Lakatta EG; Cheng H
    J Physiol; 1997 Apr; 500 ( Pt 2)(Pt 2):343-54. PubMed ID: 9147322
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Calcium dysregulation via L-type voltage-dependent calcium channels and ryanodine receptors underlies memory deficits and synaptic dysfunction during chronic neuroinflammation.
    Hopp SC; D'Angelo HM; Royer SE; Kaercher RM; Crockett AM; Adzovic L; Wenk GL
    J Neuroinflammation; 2015 Mar; 12():56. PubMed ID: 25888781
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.