BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

169 related articles for article (PubMed ID: 21290468)

  • 21. MRE11-RAD50-NBS1 is a critical regulator of FANCD2 stability and function during DNA double-strand break repair.
    Roques C; Coulombe Y; Delannoy M; Vignard J; Grossi S; Brodeur I; Rodrigue A; Gautier J; Stasiak AZ; Stasiak A; Constantinou A; Masson JY
    EMBO J; 2009 Aug; 28(16):2400-13. PubMed ID: 19609304
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Transcription-coupled DNA double-strand breaks are mediated via the nucleotide excision repair and the Mre11-Rad50-Nbs1 complex.
    Guirouilh-Barbat J; Redon C; Pommier Y
    Mol Biol Cell; 2008 Sep; 19(9):3969-81. PubMed ID: 18632984
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Adenovirus regulates sumoylation of Mre11-Rad50-Nbs1 components through a paralog-specific mechanism.
    Sohn SY; Hearing P
    J Virol; 2012 Sep; 86(18):9656-65. PubMed ID: 22740413
    [TBL] [Abstract][Full Text] [Related]  

  • 24. ATM and the Mre11-Rad50-Nbs1 complex respond to nucleoside analogue-induced stalled replication forks and contribute to drug resistance.
    Ewald B; Sampath D; Plunkett W
    Cancer Res; 2008 Oct; 68(19):7947-55. PubMed ID: 18829552
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Bcl2 inhibits recruitment of Mre11 complex to DNA double-strand breaks in response to high-linear energy transfer radiation.
    Xie M; Park D; You S; Li R; Owonikoko TK; Wang Y; Doetsch PW; Deng X
    Nucleic Acids Res; 2015 Jan; 43(2):960-72. PubMed ID: 25567982
    [TBL] [Abstract][Full Text] [Related]  

  • 26. ATP puts the brake on DNA double-strand break repair: a new study shows that ATP switches the Mre11-Rad50-Nbs1 repair factor between signaling and processing of DNA ends.
    Hopfner KP
    Bioessays; 2014 Dec; 36(12):1170-8. PubMed ID: 25213441
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Targeting Rad50 sensitizes human nasopharyngeal carcinoma cells to radiotherapy.
    Chang L; Huang J; Wang K; Li J; Yan R; Zhu L; Ye J; Wu X; Zhuang S; Li D; Zhang G
    BMC Cancer; 2016 Mar; 16():190. PubMed ID: 26951044
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Independent roles for nibrin and Mre11-Rad50 in the activation and function of Atm.
    Cerosaletti K; Concannon P
    J Biol Chem; 2004 Sep; 279(37):38813-9. PubMed ID: 15234984
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Visualization of local DNA unwinding by Mre11/Rad50/Nbs1 using single-molecule FRET.
    Cannon B; Kuhnlein J; Yang SH; Cheng A; Schindler D; Stark JM; Russell R; Paull TT
    Proc Natl Acad Sci U S A; 2013 Nov; 110(47):18868-73. PubMed ID: 24191051
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Replication protein A is required for etoposide-induced assembly of MRE11/RAD50/NBS1 complex repair foci.
    Robison JG; Bissler JJ; Dixon K
    Cell Cycle; 2007 Oct; 6(19):2408-16. PubMed ID: 17700070
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Ataxia telangiectasia-mutated (ATM) kinase activity is regulated by ATP-driven conformational changes in the Mre11/Rad50/Nbs1 (MRN) complex.
    Lee JH; Mand MR; Deshpande RA; Kinoshita E; Yang SH; Wyman C; Paull TT
    J Biol Chem; 2013 May; 288(18):12840-51. PubMed ID: 23525106
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Fanconi anemia group J helicase and MRE11 nuclease interact to facilitate the DNA damage response.
    Suhasini AN; Sommers JA; Muniandy PA; Coulombe Y; Cantor SB; Masson JY; Seidman MM; Brosh RM
    Mol Cell Biol; 2013 Jun; 33(11):2212-27. PubMed ID: 23530059
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Breast cancer risk is associated with the genes encoding the DNA double-strand break repair Mre11/Rad50/Nbs1 complex.
    Hsu HM; Wang HC; Chen ST; Hsu GC; Shen CY; Yu JC
    Cancer Epidemiol Biomarkers Prev; 2007 Oct; 16(10):2024-32. PubMed ID: 17932350
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Rad50 zinc hook is important for the Mre11 complex to bind chromosomal DNA double-stranded breaks and initiate various DNA damage responses.
    He J; Shi LZ; Truong LN; Lu CS; Razavian N; Li Y; Negrete A; Shiloach J; Berns MW; Wu X
    J Biol Chem; 2012 Sep; 287(38):31747-56. PubMed ID: 22833675
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Transfection of human tumour cells with Mre11 siRNA and the increase in radiation sensitivity and the reduction in heat-induced radiosensitization.
    Xu M; Myerson RJ; Hunt C; Kumar S; Moros EG; Straube WL; Roti Roti JL
    Int J Hyperthermia; 2004 Mar; 20(2):157-62. PubMed ID: 15195510
    [TBL] [Abstract][Full Text] [Related]  

  • 36. The Mre11/Rad50/Nbs1 complex plays an important role in the prevention of DNA rereplication in mammalian cells.
    Lee AY; Liu E; Wu X
    J Biol Chem; 2007 Nov; 282(44):32243-55. PubMed ID: 17715134
    [TBL] [Abstract][Full Text] [Related]  

  • 37. High resolution imaging of changes in the structure and spatial organization of chromatin, gamma-H2A.X and the MRN complex within etoposide-induced DNA repair foci.
    Dellaire G; Kepkay R; Bazett-Jones DP
    Cell Cycle; 2009 Nov; 8(22):3750-69. PubMed ID: 19855159
    [TBL] [Abstract][Full Text] [Related]  

  • 38. NBS1 promotes the endonuclease activity of the MRE11-RAD50 complex by sensing CtIP phosphorylation.
    Anand R; Jasrotia A; Bundschuh D; Howard SM; Ranjha L; Stucki M; Cejka P
    EMBO J; 2019 Apr; 38(7):. PubMed ID: 30787182
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Focus formation of DNA repair proteins in normal and repair-deficient cells irradiated with high-LET ions.
    Karlsson KH; Stenerlöw B
    Radiat Res; 2004 May; 161(5):517-27. PubMed ID: 15161372
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Sp1 facilitates DNA double-strand break repair through a nontranscriptional mechanism.
    Beishline K; Kelly CM; Olofsson BA; Koduri S; Emrich J; Greenberg RA; Azizkhan-Clifford J
    Mol Cell Biol; 2012 Sep; 32(18):3790-9. PubMed ID: 22826432
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.