BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

196 related articles for article (PubMed ID: 21294646)

  • 1. Ataxia telangiectasia and Rad3-related overexpressing cancer cells induce prolonged G₂ arrest and develop resistance to ionizing radiation.
    Kim YM; Lee YM; Park SY; Pyo H
    DNA Cell Biol; 2011 Apr; 30(4):219-27. PubMed ID: 21294646
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hsp90 inhibitor-mediated disruption of chaperone association of ATR with hsp90 sensitizes cancer cells to DNA damage.
    Ha K; Fiskus W; Rao R; Balusu R; Venkannagari S; Nalabothula NR; Bhalla KN
    Mol Cancer Ther; 2011 Jul; 10(7):1194-206. PubMed ID: 21566061
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cyclooxygenase-2 up-regulates ataxia telangiectasia and Rad3 related through extracellular signal-regulated kinase activation.
    Kim YM; Lee EJ; Park SY; Cho KH; Kim JY; Pyo H
    Mol Cancer Res; 2009 Jul; 7(7):1158-68. PubMed ID: 19584262
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ataxia-telangiectasia-mutated (ATM) and NBS1-dependent phosphorylation of Chk1 on Ser-317 in response to ionizing radiation.
    Gatei M; Sloper K; Sorensen C; Syljuäsen R; Falck J; Hobson K; Savage K; Lukas J; Zhou BB; Bartek J; Khanna KK
    J Biol Chem; 2003 Apr; 278(17):14806-11. PubMed ID: 12588868
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ionizing radiation-dependent gamma-H2AX focus formation requires ataxia telangiectasia mutated and ataxia telangiectasia mutated and Rad3-related.
    Friesner JD; Liu B; Culligan K; Britt AB
    Mol Biol Cell; 2005 May; 16(5):2566-76. PubMed ID: 15772150
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ataxia telangiectasia-mutated-Rad3-related DNA damage checkpoint signaling pathway triggered by hepatitis B virus infection.
    Zhao F; Hou NB; Yang XL; He X; Liu Y; Zhang YH; Wei CW; Song T; Li L; Ma QJ; Zhong H
    World J Gastroenterol; 2008 Oct; 14(40):6163-70. PubMed ID: 18985806
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Irradiation-induced G2/M checkpoint response requires ERK1/2 activation.
    Yan Y; Black CP; Cowan KH
    Oncogene; 2007 Jul; 26(32):4689-98. PubMed ID: 17297454
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Tachpyridine, a metal chelator, induces G2 cell-cycle arrest, activates checkpoint kinases, and sensitizes cells to ionizing radiation.
    Turner J; Koumenis C; Kute TE; Planalp RP; Brechbiel MW; Beardsley D; Cody B; Brown KD; Torti FM; Torti SV
    Blood; 2005 Nov; 106(9):3191-9. PubMed ID: 16014567
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Depletion of ATR selectively sensitizes ATM-deficient human mammary epithelial cells to ionizing radiation and DNA-damaging agents.
    Cui Y; Palii SS; Innes CL; Paules RS
    Cell Cycle; 2014; 13(22):3541-50. PubMed ID: 25483091
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Modulation of ionizing radiation-induced G2 arrest by cyclooxygenase-2 and its inhibitor celecoxib.
    Jun HJ; Kim YM; Park SY; Park JS; Lee EJ; Choi SA; Pyo H
    Int J Radiat Oncol Biol Phys; 2009 Sep; 75(1):225-34. PubMed ID: 19695440
    [TBL] [Abstract][Full Text] [Related]  

  • 11. DNA protein kinase-dependent G2 checkpoint revealed following knockdown of ataxia-telangiectasia mutated in human mammary epithelial cells.
    Arlander SJ; Greene BT; Innes CL; Paules RS
    Cancer Res; 2008 Jan; 68(1):89-97. PubMed ID: 18172300
    [TBL] [Abstract][Full Text] [Related]  

  • 12. BRCA1-BARD1 complexes are required for p53Ser-15 phosphorylation and a G1/S arrest following ionizing radiation-induced DNA damage.
    Fabbro M; Savage K; Hobson K; Deans AJ; Powell SN; McArthur GA; Khanna KK
    J Biol Chem; 2004 Jul; 279(30):31251-8. PubMed ID: 15159397
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Requirement of MTA1 in ATR-mediated DNA damage checkpoint function.
    Li DQ; Ohshiro K; Khan MN; Kumar R
    J Biol Chem; 2010 Jun; 285(26):19802-12. PubMed ID: 20427275
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phosphatase type 2A-dependent and -independent pathways for ATR phosphorylation of Chk1.
    Li G; Elder RT; Qin K; Park HU; Liang D; Zhao RY
    J Biol Chem; 2007 Mar; 282(10):7287-98. PubMed ID: 17210576
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 4-Hydroxynonenal induces G2/M phase cell cycle arrest by activation of the ataxia telangiectasia mutated and Rad3-related protein (ATR)/checkpoint kinase 1 (Chk1) signaling pathway.
    Chaudhary P; Sharma R; Sahu M; Vishwanatha JK; Awasthi S; Awasthi YC
    J Biol Chem; 2013 Jul; 288(28):20532-46. PubMed ID: 23733185
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SHP-1 overexpression increases the radioresistance of NPC cells by enhancing DSB repair, increasing S phase arrest and decreasing cell apoptosis.
    Pan X; Mou J; Liu S; Sun Z; Meng R; Zhou Z; Wu G; Peng G
    Oncol Rep; 2015 Jun; 33(6):2999-3005. PubMed ID: 25962492
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ataxia telangiectasia mutated (ATM) kinase and ATM and Rad3 related kinase mediate phosphorylation of Brca1 at distinct and overlapping sites. In vivo assessment using phospho-specific antibodies.
    Gatei M; Zhou BB; Hobson K; Scott S; Young D; Khanna KK
    J Biol Chem; 2001 May; 276(20):17276-80. PubMed ID: 11278964
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance.
    Brown EJ; Baltimore D
    Genes Dev; 2003 Mar; 17(5):615-28. PubMed ID: 12629044
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint response.
    Zhang X; Succi J; Feng Z; Prithivirajsingh S; Story MD; Legerski RJ
    Mol Cell Biol; 2004 Oct; 24(20):9207-20. PubMed ID: 15456891
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mismatch repair-dependent G2 checkpoint induced by low doses of SN1 type methylating agents requires the ATR kinase.
    Stojic L; Mojas N; Cejka P; Di Pietro M; Ferrari S; Marra G; Jiricny J
    Genes Dev; 2004 Jun; 18(11):1331-44. PubMed ID: 15175264
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.