168 related articles for article (PubMed ID: 21295584)
1. HIV-1 integrase strand transfer inhibitors stabilize an integrase-single blunt-ended DNA complex.
Bera S; Pandey KK; Vora AC; Grandgenett DP
J Mol Biol; 2011 Jul; 410(5):831-46. PubMed ID: 21295584
[TBL] [Abstract][Full Text] [Related]
2. Molecular Interactions between HIV-1 integrase and the two viral DNA ends within the synaptic complex that mediates concerted integration.
Bera S; Pandey KK; Vora AC; Grandgenett DP
J Mol Biol; 2009 May; 389(1):183-98. PubMed ID: 19362096
[TBL] [Abstract][Full Text] [Related]
3. Physical trapping of HIV-1 synaptic complex by different structural classes of integrase strand transfer inhibitors.
Pandey KK; Bera S; Vora AC; Grandgenett DP
Biochemistry; 2010 Sep; 49(38):8376-87. PubMed ID: 20799722
[TBL] [Abstract][Full Text] [Related]
4. Mechanisms of human immunodeficiency virus type 1 concerted integration related to strand transfer inhibition and drug resistance.
Zahm JA; Bera S; Pandey KK; Vora A; Stillmock K; Hazuda D; Grandgenett DP
Antimicrob Agents Chemother; 2008 Sep; 52(9):3358-68. PubMed ID: 18591263
[TBL] [Abstract][Full Text] [Related]
5. Unprocessed viral DNA could be the primary target of the HIV-1 integrase inhibitor raltegravir.
Ammar FF; Abdel-Azeim S; Zargarian L; Hobaika Z; Maroun RG; Fermandjian S
PLoS One; 2012; 7(7):e40223. PubMed ID: 22768342
[TBL] [Abstract][Full Text] [Related]
6. Inhibition of human immunodeficiency virus type 1 concerted integration by strand transfer inhibitors which recognize a transient structural intermediate.
Pandey KK; Bera S; Zahm J; Vora A; Stillmock K; Hazuda D; Grandgenett DP
J Virol; 2007 Nov; 81(22):12189-99. PubMed ID: 17804497
[TBL] [Abstract][Full Text] [Related]
7. DNA damage enhances integration of HIV-1 into macrophages by overcoming integrase inhibition.
Koyama T; Sun B; Tokunaga K; Tatsumi M; Ishizaka Y
Retrovirology; 2013 Feb; 10():21. PubMed ID: 23432899
[TBL] [Abstract][Full Text] [Related]
8. Dolutegravir-Selected HIV-1 Containing the N155H and R263K Resistance Substitutions Does Not Acquire Additional Compensatory Mutations under Drug Pressure That Lead to Higher-Level Resistance and Increased Replicative Capacity.
Anstett K; Fusco R; Cutillas V; Mesplède T; Wainberg MA
J Virol; 2015 Oct; 89(20):10482-8. PubMed ID: 26246578
[TBL] [Abstract][Full Text] [Related]
9. Selectivity for strand-transfer over 3'-processing and susceptibility to clinical resistance of HIV-1 integrase inhibitors are driven by key enzyme-DNA interactions in the active site.
Métifiot M; Johnson BC; Kiselev E; Marler L; Zhao XZ; Burke TR; Marchand C; Hughes SH; Pommier Y
Nucleic Acids Res; 2016 Aug; 44(14):6896-906. PubMed ID: 27369381
[TBL] [Abstract][Full Text] [Related]
10. Rous sarcoma virus synaptic complex capable of concerted integration is kinetically trapped by human immunodeficiency virus integrase strand transfer inhibitors.
Pandey KK; Bera S; Korolev S; Campbell M; Yin Z; Aihara H; Grandgenett DP
J Biol Chem; 2014 Jul; 289(28):19648-58. PubMed ID: 24872410
[TBL] [Abstract][Full Text] [Related]
11. The HIV-1 integrase monomer induces a specific interaction with LTR DNA for concerted integration.
Pandey KK; Bera S; Grandgenett DP
Biochemistry; 2011 Nov; 50(45):9788-96. PubMed ID: 21992419
[TBL] [Abstract][Full Text] [Related]
12. Characterization of the Drug Resistance Profiles of Integrase Strand Transfer Inhibitors in Simian Immunodeficiency Virus SIVmac239.
Hassounah SA; Liu Y; Quashie PK; Oliveira M; Moisi D; Brenner BG; Sandstrom PA; Mesplède T; Wainberg MA
J Virol; 2015 Dec; 89(23):12002-13. PubMed ID: 26378179
[TBL] [Abstract][Full Text] [Related]
13. The HIV-1 integrase mutations Y143C/R are an alternative pathway for resistance to Raltegravir and impact the enzyme functions.
Reigadas S; Anies G; Masquelier B; Calmels C; Stuyver LJ; Parissi V; Fleury H; Andreola ML
PLoS One; 2010 Apr; 5(4):e10311. PubMed ID: 20436677
[TBL] [Abstract][Full Text] [Related]
14. Resistance to raltegravir highlights integrase mutations at codon 148 in conferring cross-resistance to a second-generation HIV-1 integrase inhibitor.
Goethals O; Van Ginderen M; Vos A; Cummings MD; Van Der Borght K; Van Wesenbeeck L; Feyaerts M; Verheyen A; Smits V; Van Loock M; Hertogs K; Schols D; Clayton RF
Antiviral Res; 2011 Aug; 91(2):167-76. PubMed ID: 21669228
[TBL] [Abstract][Full Text] [Related]
15. In vitro analysis of the susceptibility of HIV-1 subtype A and CRF01_AE integrases to raltegravir.
Bellecave P; Malato L; Calmels C; Reigadas S; Parissi V; Andreola ML; Fleury H
Int J Antimicrob Agents; 2014 Aug; 44(2):168-72. PubMed ID: 24935032
[TBL] [Abstract][Full Text] [Related]
16. Comparative biochemical analysis of HIV-1 subtype B and C integrase enzymes.
Bar-Magen T; Sloan RD; Faltenbacher VH; Donahue DA; Kuhl BD; Oliveira M; Xu H; Wainberg MA
Retrovirology; 2009 Nov; 6():103. PubMed ID: 19906306
[TBL] [Abstract][Full Text] [Related]
17. Longitudinal analysis of integrase N155H variants in heavily treated patients failing raltegravir-based regimens.
Nguyen HL; Charpentier C; Nguyen N; de Truchis P; Molina JM; Ruxrungtham K; Delaugerre C
HIV Med; 2013 Feb; 14(2):85-91. PubMed ID: 22994529
[TBL] [Abstract][Full Text] [Related]
18. Mutations associated with failure of raltegravir treatment affect integrase sensitivity to the inhibitor in vitro.
Malet I; Delelis O; Valantin MA; Montes B; Soulie C; Wirden M; Tchertanov L; Peytavin G; Reynes J; Mouscadet JF; Katlama C; Calvez V; Marcelin AG
Antimicrob Agents Chemother; 2008 Apr; 52(4):1351-8. PubMed ID: 18227187
[TBL] [Abstract][Full Text] [Related]
19. Changes to the HIV long terminal repeat and to HIV integrase differentially impact HIV integrase assembly, activity, and the binding of strand transfer inhibitors.
Dicker IB; Samanta HK; Li Z; Hong Y; Tian Y; Banville J; Remillard RR; Walker MA; Langley DR; Krystal M
J Biol Chem; 2007 Oct; 282(43):31186-96. PubMed ID: 17715137
[TBL] [Abstract][Full Text] [Related]
20. Multimode, cooperative mechanism of action of allosteric HIV-1 integrase inhibitors.
Kessl JJ; Jena N; Koh Y; Taskent-Sezgin H; Slaughter A; Feng L; de Silva S; Wu L; Le Grice SF; Engelman A; Fuchs JR; Kvaratskhelia M
J Biol Chem; 2012 May; 287(20):16801-11. PubMed ID: 22437836
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
