102 related articles for article (PubMed ID: 21297302)
1. Structure-activity relationships of new N-acylanthranilic acid derivatives as plasminogen activator inhibitor-1 inhibitors.
Yamaoka N; Kodama H; Izuhara Y; Miyata T; Meguro K
Chem Pharm Bull (Tokyo); 2011; 59(2):215-24. PubMed ID: 21297302
[TBL] [Abstract][Full Text] [Related]
2. Identification of novel plasminogen activator inhibitor-1 inhibitors with improved oral bioavailability: Structure optimization of N-acylanthranilic acid derivatives.
Yamaoka N; Murano K; Kodama H; Maeda A; Dan T; Nakabayashi T; Miyata T; Meguro K
Bioorg Med Chem Lett; 2018 Feb; 28(4):809-813. PubMed ID: 29366646
[TBL] [Abstract][Full Text] [Related]
3. A novel inhibitor of plasminogen activator inhibitor-1 provides antithrombotic benefits devoid of bleeding effect in nonhuman primates.
Izuhara Y; Yamaoka N; Kodama H; Dan T; Takizawa S; Hirayama N; Meguro K; van Ypersele de Strihou C; Miyata T
J Cereb Blood Flow Metab; 2010 May; 30(5):904-12. PubMed ID: 20087372
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and biological evaluation of piperazine-based derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1).
Ye B; Chou YL; Karanjawala R; Lee W; Lu SF; Shaw KJ; Jones S; Lentz D; Liang A; Tseng JL; Wu Q; Zhao Z
Bioorg Med Chem Lett; 2004 Feb; 14(3):761-5. PubMed ID: 14741285
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and evaluation of pyrrolin-2-one compounds, a series of plasminogen activator inhibitor-1 inhibitors.
Miyazaki H; Ogiku T; Sai H; Moritani Y; Ohtani A; Ohmizu H
Chem Pharm Bull (Tokyo); 2009 Sep; 57(9):979-85. PubMed ID: 19721260
[TBL] [Abstract][Full Text] [Related]
6. Evaluation of pyrrolin-2-one derivatives synthesized by a new practical method as inhibitors of plasminogen activator inhibitor-1 (PAI-1).
Miyazaki H; Miyake T; Terakawa Y; Ohmizu H; Ogiku T; Ohtani A
Bioorg Med Chem Lett; 2010 Jan; 20(2):546-8. PubMed ID: 19969458
[TBL] [Abstract][Full Text] [Related]
7. Discovery of inhibitors of plasminogen activator inhibitor-1: structure-activity study of 5-nitro-2-phenoxybenzoic acid derivatives.
Pandya V; Jain M; Chakrabarti G; Soni H; Parmar B; Chaugule B; Patel J; Joshi J; Joshi N; Rath A; Raviya M; Shaikh M; Sairam KV; Patel H; Patel P
Bioorg Med Chem Lett; 2011 Oct; 21(19):5701-6. PubMed ID: 21880486
[TBL] [Abstract][Full Text] [Related]
8. Structure-activity relationships of new 2-acylamino-3-thiophenecarboxylic acid dimers as plasminogen activator inhibitor-1 inhibitors.
Yamaoka N; Kawano Y; Izuhara Y; Miyata T; Meguro K
Chem Pharm Bull (Tokyo); 2010 May; 58(5):615-9. PubMed ID: 20460785
[TBL] [Abstract][Full Text] [Related]
9. Design, synthesis, and evaluation of orally active inhibitors of plasminogen activator inhibitor-1 (PAI-1) production.
Miyazaki H; Ogiku T; Sai H; Ohmizu H; Murakami J; Ohtani A
Bioorg Med Chem Lett; 2008 Dec; 18(24):6419-22. PubMed ID: 18993062
[TBL] [Abstract][Full Text] [Related]
10. TM5275 prolongs secreted tissue plasminogen activator retention and enhances fibrinolysis on vascular endothelial cells.
Yasui H; Suzuki Y; Sano H; Suda T; Chida K; Dan T; Miyata T; Urano T
Thromb Res; 2013 Jul; 132(1):100-5. PubMed ID: 23611258
[TBL] [Abstract][Full Text] [Related]
11. Design, synthesis, and SAR of embelin analogues as the inhibitors of PAI-1 (plasminogen activator inhibitor-1).
Chen F; Zhang G; Hong Z; Lin Z; Lei M; Huang M; Hu L
Bioorg Med Chem Lett; 2014 May; 24(10):2379-82. PubMed ID: 24731276
[TBL] [Abstract][Full Text] [Related]
12. Tiplaxtinin, a novel, orally efficacious inhibitor of plasminogen activator inhibitor-1: design, synthesis, and preclinical characterization.
Elokdah H; Abou-Gharbia M; Hennan JK; McFarlane G; Mugford CP; Krishnamurthy G; Crandall DL
J Med Chem; 2004 Jul; 47(14):3491-4. PubMed ID: 15214776
[TBL] [Abstract][Full Text] [Related]
13. Design, synthesis and in vitro evaluation of potent, novel, small molecule inhibitors of plasminogen activator inhibitor-1.
Folkes A; Brown SD; Canne LE; Chan J; Engelhardt E; Epshteyn S; Faint R; Golec J; Hanel A; Kearney P; Leahy JW; Mac M; Matthews D; Prisbylla MP; Sanderson J; Simon RJ; Tesfai Z; Vicker N; Wang S; Webb RR; Charlton P
Bioorg Med Chem Lett; 2002 Apr; 12(7):1063-6. PubMed ID: 11909718
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and evaluation of 1,4-diphenylbutadiene derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1) production.
Miyazaki H; Sai H; Ohmizu H; Murakami J; Ohtani A; Ogiku T
Bioorg Med Chem; 2010 Mar; 18(5):1968-79. PubMed ID: 20138768
[TBL] [Abstract][Full Text] [Related]
15. Inhibition of PCAF histone acetyltransferase and cytotoxic effect of N-acylanthranilic acids.
Park WJ; Ma E
Arch Pharm Res; 2012 Aug; 35(8):1379-86. PubMed ID: 22941480
[TBL] [Abstract][Full Text] [Related]
16. In vitro PAI-1 inhibitory activity of oxalamide derivatives.
Jain MR; Shetty S; Chakrabarti G; Pandya V; Sharma A; Parmar B; Srivastava S; Raviya M; Soni H; Patel PR
Eur J Med Chem; 2008 Apr; 43(4):880-4. PubMed ID: 17664030
[TBL] [Abstract][Full Text] [Related]
17. Inhibitory mechanism of serpins: loop insertion forces acylation of plasminogen activator by plasminogen activator inhibitor-1.
Kvassman JO; Verhamme I; Shore JD
Biochemistry; 1998 Nov; 37(44):15491-502. PubMed ID: 9799512
[TBL] [Abstract][Full Text] [Related]
18. Novel inhibitors of plasminogen activator inhibitor-1: development of new templates from diketopiperazines.
Wang S; Golec J; Miller W; Milutinovic S; Folkes A; Williams S; Brooks T; Hardman K; Charlton P; Wren S; Spencer J
Bioorg Med Chem Lett; 2002 Sep; 12(17):2367-70. PubMed ID: 12161135
[TBL] [Abstract][Full Text] [Related]
19. A small molecule inhibitor to plasminogen activator inhibitor 1 inhibits macrophage migration.
Ichimura A; Matsumoto S; Suzuki S; Dan T; Yamaki S; Sato Y; Kiyomoto H; Ishii N; Okada K; Matsuo O; Hou FF; Vaughan DE; van Ypersele de Strihou C; Miyata T
Arterioscler Thromb Vasc Biol; 2013 May; 33(5):935-42. PubMed ID: 23471233
[TBL] [Abstract][Full Text] [Related]
20. Synthesis of new anthranilic acid dimer derivatives and their evaluation on CCK receptors.
Varnavas A; Lassiani L; Valenta V
Farmaco; 2000 May; 55(5):369-75. PubMed ID: 10983282
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
