821 related articles for article (PubMed ID: 21297615)
1. DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration.
Kaneko H; Dridi S; Tarallo V; Gelfand BD; Fowler BJ; Cho WG; Kleinman ME; Ponicsan SL; Hauswirth WW; Chiodo VA; Karikó K; Yoo JW; Lee DK; Hadziahmetovic M; Song Y; Misra S; Chaudhuri G; Buaas FW; Braun RE; Hinton DR; Zhang Q; Grossniklaus HE; Provis JM; Madigan MC; Milam AH; Justice NL; Albuquerque RJ; Blandford AD; Bogdanovich S; Hirano Y; Witta J; Fuchs E; Littman DR; Ambati BK; Rudin CM; Chong MM; Provost P; Kugel JF; Goodrich JA; Dunaief JL; Baffi JZ; Ambati J
Nature; 2011 Mar; 471(7338):325-30. PubMed ID: 21297615
[TBL] [Abstract][Full Text] [Related]
2. Vision: Dicer leaps into view.
Meister G
Nature; 2011 Mar; 471(7338):308-9. PubMed ID: 21412326
[No Abstract] [Full Text] [Related]
3. DICER1/Alu RNA dysmetabolism induces Caspase-8-mediated cell death in age-related macular degeneration.
Kim Y; Tarallo V; Kerur N; Yasuma T; Gelfand BD; Bastos-Carvalho A; Hirano Y; Yasuma R; Mizutani T; Fowler BJ; Li S; Kaneko H; Bogdanovich S; Ambati BK; Hinton DR; Hauswirth WW; Hakem R; Wright C; Ambati J
Proc Natl Acad Sci U S A; 2014 Nov; 111(45):16082-7. PubMed ID: 25349431
[TBL] [Abstract][Full Text] [Related]
4. MicroRNA-processing Enzymes Are Essential for Survival and Function of Mature Retinal Pigmented Epithelial Cells in Mice.
Sundermeier TR; Sakami S; Sahu B; Howell SJ; Gao S; Dong Z; Golczak M; Maeda A; Palczewski K
J Biol Chem; 2017 Feb; 292(8):3366-3378. PubMed ID: 28104803
[TBL] [Abstract][Full Text] [Related]
5. DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88.
Tarallo V; Hirano Y; Gelfand BD; Dridi S; Kerur N; Kim Y; Cho WG; Kaneko H; Fowler BJ; Bogdanovich S; Albuquerque RJ; Hauswirth WW; Chiodo VA; Kugel JF; Goodrich JA; Ponicsan SL; Chaudhuri G; Murphy MP; Dunaief JL; Ambati BK; Ogura Y; Yoo JW; Lee DK; Provost P; Hinton DR; Núñez G; Baffi JZ; Kleinman ME; Ambati J
Cell; 2012 May; 149(4):847-59. PubMed ID: 22541070
[TBL] [Abstract][Full Text] [Related]
6. Lutein improves cell viability and reduces Alu RNA accumulation in hydrogen peroxide challenged retinal pigment epithelial cells.
Chong YS; Mai CW; Leong CO; Wong LC
Cutan Ocul Toxicol; 2018 Mar; 37(1):52-60. PubMed ID: 28554225
[TBL] [Abstract][Full Text] [Related]
7. Chronic Dicer1 deficiency promotes atrophic and neovascular outer retinal pathologies in mice.
Wright CB; Uehara H; Kim Y; Yasuma T; Yasuma R; Hirahara S; Makin RD; Apicella I; Pereira F; Nagasaka Y; Narendran S; Fukuda S; Albuquerque R; Fowler BJ; Bastos-Carvalho A; Georgel P; Hatada I; Chang B; Kerur N; Ambati BK; Ambati J; Gelfand BD
Proc Natl Acad Sci U S A; 2020 Feb; 117(5):2579-2587. PubMed ID: 31964819
[TBL] [Abstract][Full Text] [Related]
8. ERK1/2 activation is a therapeutic target in age-related macular degeneration.
Dridi S; Hirano Y; Tarallo V; Kim Y; Fowler BJ; Ambati BK; Bogdanovich S; Chiodo VA; Hauswirth WW; Kugel JF; Goodrich JA; Ponicsan SL; Hinton DR; Kleinman ME; Baffi JZ; Gelfand BD; Ambati J
Proc Natl Acad Sci U S A; 2012 Aug; 109(34):13781-6. PubMed ID: 22869729
[TBL] [Abstract][Full Text] [Related]
9. Alu RNA accumulation induces epithelial-to-mesenchymal transition by modulating miR-566 and is associated with cancer progression.
Di Ruocco F; Basso V; Rivoire M; Mehlen P; Ambati J; De Falco S; Tarallo V
Oncogene; 2018 Feb; 37(5):627-637. PubMed ID: 28991230
[TBL] [Abstract][Full Text] [Related]
10. Iron Toxicity in the Retina Requires Alu RNA and the NLRP3 Inflammasome.
Gelfand BD; Wright CB; Kim Y; Yasuma T; Yasuma R; Li S; Fowler BJ; Bastos-Carvalho A; Kerur N; Uittenbogaard A; Han YS; Lou D; Kleinman ME; McDonald WH; Núñez G; Georgel P; Dunaief JL; Ambati J
Cell Rep; 2015 Jun; 11(11):1686-93. PubMed ID: 26074074
[TBL] [Abstract][Full Text] [Related]
11. DICER1 is essential for survival of postmitotic rod photoreceptor cells in mice.
Sundermeier TR; Zhang N; Vinberg F; Mustafi D; Kohno H; Golczak M; Bai X; Maeda A; Kefalov VJ; Palczewski K
FASEB J; 2014 Aug; 28(8):3780-91. PubMed ID: 24812086
[TBL] [Abstract][Full Text] [Related]
12. cGAS drives noncanonical-inflammasome activation in age-related macular degeneration.
Kerur N; Fukuda S; Banerjee D; Kim Y; Fu D; Apicella I; Varshney A; Yasuma R; Fowler BJ; Baghdasaryan E; Marion KM; Huang X; Yasuma T; Hirano Y; Serbulea V; Ambati M; Ambati VL; Kajiwara Y; Ambati K; Hirahara S; Bastos-Carvalho A; Ogura Y; Terasaki H; Oshika T; Kim KB; Hinton DR; Leitinger N; Cambier JC; Buxbaum JD; Kenney MC; Jazwinski SM; Nagai H; Hara I; West AP; Fitzgerald KA; Sadda SR; Gelfand BD; Ambati J
Nat Med; 2018 Jan; 24(1):50-61. PubMed ID: 29176737
[TBL] [Abstract][Full Text] [Related]
13. Cytoplasmic synthesis of endogenous
Fukuda S; Varshney A; Fowler BJ; Wang SB; Narendran S; Ambati K; Yasuma T; Magagnoli J; Leung H; Hirahara S; Nagasaka Y; Yasuma R; Apicella I; Pereira F; Makin RD; Magner E; Liu X; Sun J; Wang M; Baker K; Marion KM; Huang X; Baghdasaryan E; Ambati M; Ambati VL; Pandey A; Pandya L; Cummings T; Banerjee D; Huang P; Yerramothu P; Tolstonog GV; Held U; Erwin JA; Paquola ACM; Herdy JR; Ogura Y; Terasaki H; Oshika T; Darwish S; Singh RK; Mozaffari S; Bhattarai D; Kim KB; Hardin JW; Bennett CL; Hinton DR; Hanson TE; Röver C; Parang K; Kerur N; Liu J; Werner BC; Sutton SS; Sadda SR; Schumann GG; Gelfand BD; Gage FH; Ambati J
Proc Natl Acad Sci U S A; 2021 Feb; 118(6):. PubMed ID: 33526699
[No Abstract] [Full Text] [Related]
14. Issues with the Specificity of Immunological Reagents for NLRP3: Implications for Age-related Macular Degeneration.
Kosmidou C; Efstathiou NE; Hoang MV; Notomi S; Konstantinou EK; Hirano M; Takahashi K; Maidana DE; Tsoka P; Young L; Gragoudas ES; Olsen TW; Morizane Y; Miller JW; Vavvas DG
Sci Rep; 2018 Jan; 8(1):461. PubMed ID: 29323137
[TBL] [Abstract][Full Text] [Related]
15. TLR-independent and P2X7-dependent signaling mediate Alu RNA-induced NLRP3 inflammasome activation in geographic atrophy.
Kerur N; Hirano Y; Tarallo V; Fowler BJ; Bastos-Carvalho A; Yasuma T; Yasuma R; Kim Y; Hinton DR; Kirschning CJ; Gelfand BD; Ambati J
Invest Ophthalmol Vis Sci; 2013 Nov; 54(12):7395-401. PubMed ID: 24114535
[TBL] [Abstract][Full Text] [Related]
16. Identification of fluoxetine as a direct NLRP3 inhibitor to treat atrophic macular degeneration.
Ambati M; Apicella I; Wang SB; Narendran S; Leung H; Pereira F; Nagasaka Y; Huang P; Varshney A; Baker KL; Marion KM; Shadmehr M; Stains CI; Werner BC; Sadda SR; Taylor EW; Sutton SS; Magagnoli J; Gelfand BD
Proc Natl Acad Sci U S A; 2021 Oct; 118(41):. PubMed ID: 34620711
[TBL] [Abstract][Full Text] [Related]
17. An emerging role of Alu RNA in geographic atrophy pathogenesis: the implication for novel therapeutic strategies.
Mao X; Fang W; Liu Q
Discov Med; 2016 Dec; 22(123):337-349. PubMed ID: 28147216
[TBL] [Abstract][Full Text] [Related]
18. Systemic expression of Alu RNA in patients with geographic atrophy secondary to age-related macular degeneration.
Yoshida H; Matsushita T; Kimura E; Fujita Y; Keany R; Ikeda T; Toshimori M; Imanaka T; Nakamura M
PLoS One; 2019; 14(8):e0220887. PubMed ID: 31425537
[TBL] [Abstract][Full Text] [Related]
19. DICER1 in the Pathogenesis of Age-related Macular Degeneration (AMD) -
Kaarniranta K; Pawlowska E; Szczepanska J; Blasiak J
Aging Dis; 2020 Jul; 11(4):851-862. PubMed ID: 32765950
[TBL] [Abstract][Full Text] [Related]
20. Stop the dicing in hematopoiesis: what have we learned?
Alemdehy MF; Erkeland SJ
Cell Cycle; 2012 Aug; 11(15):2799-807. PubMed ID: 22801545
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
