BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

88 related articles for article (PubMed ID: 21299244)

  • 21. 9-Benzylidene-naphtho[2,3-b]thiophen-4-ones as novel antimicrotubule agents-synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Zuse A; Schmidt P; Baasner S; Böhm KJ; Müller K; Gerlach M; Günther EG; Unger E; Prinz H
    J Med Chem; 2006 Dec; 49(26):7816-25. PubMed ID: 17181164
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Synthesis and biological evaluation of 1-methyl-2-(3',4',5'-trimethoxybenzoyl)-3-aminoindoles as a new class of antimitotic agents and tubulin inhibitors.
    Romagnoli R; Baraldi PG; Sarkar T; Carrion MD; Cara CL; Cruz-Lopez O; Preti D; Tabrizi MA; Tolomeo M; Grimaudo S; Di Cristina A; Zonta N; Balzarini J; Brancale A; Hsieh HP; Hamel E
    J Med Chem; 2008 Mar; 51(5):1464-8. PubMed ID: 18260616
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Synthesis and biological evaluation of 2- and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization.
    Romagnoli R; Baraldi PG; Carrion MD; Lopez Cara C; Preti D; Fruttarolo F; Pavani MG; Tabrizi MA; Tolomeo M; Grimaudo S; Di Cristina A; Balzarini J; Hadfield JA; Brancale A; Hamel E
    J Med Chem; 2007 May; 50(9):2273-7. PubMed ID: 17419607
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Synthesis and structure-activity relationships of 2-amino-1-aroylnaphthalene and 2-hydroxy-1-aroylnaphthalenes as potent antitubulin agents.
    Reddy GR; Kuo CC; Tan UK; Coumar MS; Chang CY; Chiang YK; Lai MJ; Yeh JY; Wu SY; Chang JY; Liou JP; Hsieh HP
    J Med Chem; 2008 Dec; 51(24):8163-7. PubMed ID: 19053773
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Synthesis of anti-microtubule N-(2-Arylindol-7-yl)benzenesulfonamide derivatives and their antitumor mechanisms.
    Chiou CT; Chen GS; Chen ML; Li H; Shi L; Huang XH; Dai WM; Chern JW
    ChemMedChem; 2010 Sep; 5(9):1489-97. PubMed ID: 20672297
    [No Abstract]   [Full Text] [Related]  

  • 26. Preclinical antitumor activity of the oral platinum analog satraplatin.
    Wosikowski K; Lamphere L; Unteregger G; Jung V; Kaplan F; Xu JP; Rattel B; Caligiuri M
    Cancer Chemother Pharmacol; 2007 Sep; 60(4):589-600. PubMed ID: 17541592
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Immunomagnetic quantification of circulating tumor cells as a prognostic factor of androgen deprivation responsiveness in patients with hormone naive metastatic prostate cancer.
    Okegawa T; Nutahara K; Higashihara E
    J Urol; 2008 Oct; 180(4):1342-7. PubMed ID: 18707699
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Synthesis and biological evaluation of 2-(3',4',5'-trimethoxybenzoyl)-3-amino 5-aryl thiophenes as a new class of tubulin inhibitors.
    Romagnoli R; Baraldi PG; Remusat V; Carrion MD; Cara CL; Preti D; Fruttarolo F; Pavani MG; Tabrizi MA; Tolomeo M; Grimaudo S; Balzarini J; Jordan MA; Hamel E
    J Med Chem; 2006 Oct; 49(21):6425-8. PubMed ID: 17034150
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Benzoylphenylurea sulfur analogues with potent antitumor activity.
    Hallur G; Jimeno A; Dalrymple S; Zhu T; Jung MK; Hidalgo M; Isaacs JT; Sukumar S; Hamel E; Khan SR
    J Med Chem; 2006 Apr; 49(7):2357-60. PubMed ID: 16570932
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Preclinical discovery of ixabepilone, a highly active antineoplastic agent.
    Lee FY; Borzilleri R; Fairchild CR; Kamath A; Smykla R; Kramer R; Vite G
    Cancer Chemother Pharmacol; 2008 Dec; 63(1):157-66. PubMed ID: 18347795
    [TBL] [Abstract][Full Text] [Related]  

  • 31. 5-Amino-2-aroylquinolines as highly potent tubulin polymerization inhibitors.
    Nien CY; Chen YC; Kuo CC; Hsieh HP; Chang CY; Wu JS; Wu SY; Liou JP; Chang JY
    J Med Chem; 2010 Mar; 53(5):2309-13. PubMed ID: 20148562
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Arylthioindole inhibitors of tubulin polymerization. 3. Biological evaluation, structure-activity relationships and molecular modeling studies.
    La Regina G; Edler MC; Brancale A; Kandil S; Coluccia A; Piscitelli F; Hamel E; De Martino G; Matesanz R; Díaz JF; Scovassi AI; Prosperi E; Lavecchia A; Novellino E; Artico M; Silvestri R
    J Med Chem; 2007 Jun; 50(12):2865-74. PubMed ID: 17497841
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Efficacy of microtubule-active drugs followed by ketoconazole in human metastatic prostate cancer cell lines.
    Blagosklonny MV; Dixon SC; Figg WD
    J Urol; 2000 Mar; 163(3):1022-6. PubMed ID: 10688042
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Synthesis and structure-activity relationships of 1,2,4-triazoles as a novel class of potent tubulin polymerization inhibitors.
    Ouyang X; Chen X; Piatnitski EL; Kiselyov AS; He HY; Mao Y; Pattaropong V; Yu Y; Kim KH; Kincaid J; Smith L; Wong WC; Lee SP; Milligan DL; Malikzay A; Fleming J; Gerlak J; Deevi D; Doody JF; Chiang HH; Patel SN; Wang Y; Rolser RL; Kussie P; Labelle M; Tuma MC
    Bioorg Med Chem Lett; 2005 Dec; 15(23):5154-9. PubMed ID: 16198562
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Novel diarylsulfonylurea derivatives as potent antimitotic agents.
    Kim S; Park JH; Koo SY; Kim JI; Kim MH; Kim JE; Jo K; Choi HG; Lee SB; Jung SH
    Bioorg Med Chem Lett; 2004 Dec; 14(24):6075-8. PubMed ID: 15546733
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Synthesis, molecular modeling and biological evaluation of dithiocarbamates as novel antitubulin agents.
    Qian Y; Ma GY; Yang Y; Cheng K; Zheng QZ; Mao WJ; Shi L; Zhao J; Zhu HL
    Bioorg Med Chem; 2010 Jun; 18(12):4310-6. PubMed ID: 20493717
    [TBL] [Abstract][Full Text] [Related]  

  • 37. 4-(3-Halo/amino-4,5-dimethoxyphenyl)-5-aryloxazoles and -N-methylimidazoles that are cytotoxic against combretastatin A resistant tumor cells and vascular disrupting in a cisplatin resistant germ cell tumor model.
    Schobert R; Biersack B; Dietrich A; Effenberger K; Knauer S; Mueller T
    J Med Chem; 2010 Sep; 53(18):6595-602. PubMed ID: 20731355
    [TBL] [Abstract][Full Text] [Related]  

  • 38. 20-Cyclopropyl-cholecalciferol vitamin D3 analogs: a unique class of potent inhibitors of proliferation of human prostate, breast and myeloid leukemia cell lines.
    Koike M; Koshizuka K; Kawabata H; Yang R; Taub HE; Said J; Uskokovic M; Tsuruoka N; Koeffler HP
    Anticancer Res; 1999; 19(3A):1689-97. PubMed ID: 10470102
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Potent inhibition of tubulin polymerisation and proliferation of paclitaxel-resistant 1A9PTX22 human ovarian cancer cells by albendazole.
    Chu SW; Badar S; Morris DL; Pourgholami MH
    Anticancer Res; 2009 Oct; 29(10):3791-6. PubMed ID: 19846910
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Synthesis and antiproliferative evaluation of pyrazolo[1,5-a]-1,3,5-triazine myoseverin derivatives.
    Popowycz F; Schneider C; Debonis S; Skoufias DA; Kozielski F; Galmarini CM; Joseph B
    Bioorg Med Chem; 2009 May; 17(9):3471-8. PubMed ID: 19349183
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 5.