BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 21299459)

  • 1. Regulation of mammalian target of rapamycin and mitogen activated protein kinase pathways by BCR-ABL.
    Redig AJ; Vakana E; Platanias LC
    Leuk Lymphoma; 2011 Feb; 52 Suppl 1():45-53. PubMed ID: 21299459
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Compensatory PI3-kinase/Akt/mTor activation regulates imatinib resistance development.
    Burchert A; Wang Y; Cai D; von Bubnoff N; Paschka P; Müller-Brüsselbach S; Ottmann OG; Duyster J; Hochhaus A; Neubauer A
    Leukemia; 2005 Oct; 19(10):1774-82. PubMed ID: 16136169
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pharmacologic mitogen-activated protein/extracellular signal-regulated kinase kinase/mitogen-activated protein kinase inhibitors interact synergistically with STI571 to induce apoptosis in Bcr/Abl-expressing human leukemia cells.
    Yu C; Krystal G; Varticovksi L; McKinstry R; Rahmani M; Dent P; Grant S
    Cancer Res; 2002 Jan; 62(1):188-99. PubMed ID: 11782377
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Curcumin potentiates the anti-leukemia effects of imatinib by downregulation of the AKT/mTOR pathway and BCR/ABL gene expression in Ph+ acute lymphoblastic leukemia.
    Guo Y; Li Y; Shan Q; He G; Lin J; Gong Y
    Int J Biochem Cell Biol; 2015 Aug; 65():1-11. PubMed ID: 25979368
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Selective pyrrolo-pyrimidine inhibitors reveal a necessary role for Src family kinases in Bcr-Abl signal transduction and oncogenesis.
    Wilson MB; Schreiner SJ; Choi HJ; Kamens J; Smithgall TE
    Oncogene; 2002 Nov; 21(53):8075-88. PubMed ID: 12444544
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Critical roles for mTORC2- and rapamycin-insensitive mTORC1-complexes in growth and survival of BCR-ABL-expressing leukemic cells.
    Carayol N; Vakana E; Sassano A; Kaur S; Goussetis DJ; Glaser H; Druker BJ; Donato NJ; Altman JK; Barr S; Platanias LC
    Proc Natl Acad Sci U S A; 2010 Jul; 107(28):12469-74. PubMed ID: 20616057
    [TBL] [Abstract][Full Text] [Related]  

  • 7. EPS8 regulates proliferation, apoptosis and chemosensitivity in BCR-ABL positive cells via the BCR-ABL/PI3K/AKT/mTOR pathway.
    Huang R; Liu H; Chen Y; He Y; Kang Q; Tu S; He Y; Zhou X; Wang L; Yang J; Wu A; Li Y
    Oncol Rep; 2018 Jan; 39(1):119-128. PubMed ID: 29192326
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A novel Bcr-Abl-mTOR-eIF4A axis regulates IRES-mediated translation of LEF-1.
    Tsai BP; Jimenez J; Lim S; Fitzgerald KD; Zhang M; Chuah CT; Axelrod H; Wilson L; Ong ST; Semler BL; Waterman ML
    Open Biol; 2014 Nov; 4(11):140180. PubMed ID: 25392452
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Bcr-Abl regulates osteopontin transcription via Ras, PI-3K, aPKC, Raf-1, and MEK.
    Hickey FB; England K; Cotter TG
    J Leukoc Biol; 2005 Jul; 78(1):289-300. PubMed ID: 15857938
    [TBL] [Abstract][Full Text] [Related]  

  • 10. p62(dok), a negative regulator of Ras and mitogen-activated protein kinase (MAPK) activity, opposes leukemogenesis by p210(bcr-abl).
    Di Cristofano A; Niki M; Zhao M; Karnell FG; Clarkson B; Pear WS; Van Aelst L; Pandolfi PP
    J Exp Med; 2001 Aug; 194(3):275-84. PubMed ID: 11489947
    [TBL] [Abstract][Full Text] [Related]  

  • 11. GCKR links the Bcr-Abl oncogene and Ras to the stress-activated protein kinase pathway.
    Shi CS; Tuscano JM; Witte ON; Kehrl JH
    Blood; 1999 Feb; 93(4):1338-45. PubMed ID: 9949177
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Regulatory effects of sestrin 3 (SESN3) in BCR-ABL expressing cells.
    Vakana E; Arslan AD; Szilard A; Altman JK; Platanias LC
    PLoS One; 2013; 8(11):e78780. PubMed ID: 24260131
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeting Hedgehog signaling pathway and autophagy overcomes drug resistance of BCR-ABL-positive chronic myeloid leukemia.
    Zeng X; Zhao H; Li Y; Fan J; Sun Y; Wang S; Wang Z; Song P; Ju D
    Autophagy; 2015; 11(2):355-72. PubMed ID: 25701353
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Gab2 signaling in chronic myeloid leukemia cells confers resistance to multiple Bcr-Abl inhibitors.
    Wöhrle FU; Halbach S; Aumann K; Schwemmers S; Braun S; Auberger P; Schramek D; Penninger JM; Laßmann S; Werner M; Waller CF; Pahl HL; Zeiser R; Daly RJ; Brummer T
    Leukemia; 2013 Jan; 27(1):118-29. PubMed ID: 22858987
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MicroRNAs mediated regulation of MAPK signaling pathways in chronic myeloid leukemia.
    Chakraborty C; Sharma AR; Patra BC; Bhattacharya M; Sharma G; Lee SS
    Oncotarget; 2016 Jul; 7(27):42683-42697. PubMed ID: 26967056
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Blockade of Y177 and Nuclear Translocation of Bcr-Abl Inhibits Proliferation and Promotes Apoptosis in Chronic Myeloid Leukemia Cells.
    Li Q; Huang Z; Gao M; Cao W; Xiao Q; Luo H; Feng W
    Int J Mol Sci; 2017 Mar; 18(3):. PubMed ID: 28257089
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel pathway in Bcr-Abl signal transduction involves Akt-independent, PLC-gamma1-driven activation of mTOR/p70S6-kinase pathway.
    Markova B; Albers C; Breitenbuecher F; Melo JV; Brümmendorf TH; Heidel F; Lipka D; Duyster J; Huber C; Fischer T
    Oncogene; 2010 Feb; 29(5):739-51. PubMed ID: 19881535
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Selective inhibition of cell proliferation and BCR-ABL phosphorylation in acute lymphoblastic leukemia cells expressing Mr 190,000 BCR-ABL protein by a tyrosine kinase inhibitor (CGP-57148).
    Beran M; Cao X; Estrov Z; Jeha S; Jin G; O'Brien S; Talpaz M; Arlinghaus RB; Lydon NB; Kantarjian H
    Clin Cancer Res; 1998 Jul; 4(7):1661-72. PubMed ID: 9676840
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of mTOR as a novel bifunctional target in chronic myeloid leukemia: dissection of growth-inhibitory and VEGF-suppressive effects of rapamycin in leukemic cells.
    Mayerhofer M; Aichberger KJ; Florian S; Krauth MT; Hauswirth AW; Derdak S; Sperr WR; Esterbauer H; Wagner O; Marosi C; Pickl WF; Deininger M; Weisberg E; Druker BJ; Griffin JD; Sillaber C; Valent P
    FASEB J; 2005 Jun; 19(8):960-2. PubMed ID: 15784722
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bcr-Abl kinase modulates the translation regulators ribosomal protein S6 and 4E-BP1 in chronic myelogenous leukemia cells via the mammalian target of rapamycin.
    Ly C; Arechiga AF; Melo JV; Walsh CM; Ong ST
    Cancer Res; 2003 Sep; 63(18):5716-22. PubMed ID: 14522890
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.