BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

385 related articles for article (PubMed ID: 21300025)

  • 21. Identification of epigallocatechin-3-gallate in green tea polyphenols as a potent inducer of p53-dependent apoptosis in the human lung cancer cell line A549.
    Yamauchi R; Sasaki K; Yoshida K
    Toxicol In Vitro; 2009 Aug; 23(5):834-9. PubMed ID: 19406223
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Green tea polyphenol EGCG suppresses cigarette smoke condensate-induced NF-kappaB activation in normal human bronchial epithelial cells.
    Syed DN; Afaq F; Kweon MH; Hadi N; Bhatia N; Spiegelman VS; Mukhtar H
    Oncogene; 2007 Feb; 26(5):673-82. PubMed ID: 16862172
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Green tea (-)-epigallocatechin gallate inhibits the growth of human villous trophoblasts via the ERK, p38, AMP-activated protein kinase, and protein kinase B pathways.
    Shih LJ; Chen TF; Lin CK; Liu HS; Kao YH
    Am J Physiol Cell Physiol; 2016 Aug; 311(2):C308-21. PubMed ID: 27147558
    [TBL] [Abstract][Full Text] [Related]  

  • 24. WJD008, a dual phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin inhibitor, prevents PI3K signaling and inhibits the proliferation of transformed cells with oncogenic PI3K mutant.
    Li T; Wang J; Wang X; Yang N; Chen SM; Tong LJ; Yang CH; Meng LH; Ding J
    J Pharmacol Exp Ther; 2010 Sep; 334(3):830-8. PubMed ID: 20522531
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Implication of Akt, ERK1/2 and alternative p38MAPK signalling pathways in human colon cancer cell apoptosis induced by green tea EGCG.
    Cerezo-Guisado MI; Zur R; Lorenzo MJ; Risco A; Martín-Serrano MA; Alvarez-Barrientos A; Cuenda A; Centeno F
    Food Chem Toxicol; 2015 Oct; 84():125-32. PubMed ID: 26303273
    [TBL] [Abstract][Full Text] [Related]  

  • 26. New inhibitors of the PI3K-Akt-mTOR pathway: insights into mTOR signaling from a new generation of Tor Kinase Domain Inhibitors (TORKinibs).
    Feldman ME; Shokat KM
    Curr Top Microbiol Immunol; 2010; 347():241-62. PubMed ID: 20549474
    [TBL] [Abstract][Full Text] [Related]  

  • 27. The dual PI3K/mTOR inhibitor BEZ235 is effective in lung cancer cell lines.
    Herrera VA; Zeindl-Eberhart E; Jung A; Huber RM; Bergner A
    Anticancer Res; 2011 Mar; 31(3):849-54. PubMed ID: 21498705
    [TBL] [Abstract][Full Text] [Related]  

  • 28. (-)-Epigallocatechin-3-gallate promotes pro-matrix metalloproteinase-7 production via activation of the JNK1/2 pathway in HT-29 human colorectal cancer cells.
    Kim M; Murakami A; Kawabata K; Ohigashi H
    Carcinogenesis; 2005 Sep; 26(9):1553-62. PubMed ID: 15860507
    [TBL] [Abstract][Full Text] [Related]  

  • 29. 4-methylpteridinones as orally active and selective PI3K/mTOR dual inhibitors.
    Liu KK; Bagrodia S; Bailey S; Cheng H; Chen H; Gao L; Greasley S; Hoffman JE; Hu Q; Johnson TO; Knighton D; Liu Z; Marx MA; Nambu MD; Ninkovic S; Pascual B; Rafidi K; Rodgers CM; Smith GL; Sun S; Wang H; Yang A; Yuan J; Zou A
    Bioorg Med Chem Lett; 2010 Oct; 20(20):6096-9. PubMed ID: 20817449
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Epigallocatechin-3-gallate (EGCG) attenuates inflammation in MRL/lpr mouse mesangial cells.
    Peairs A; Dai R; Gan L; Shimp S; Rylander MN; Li L; Reilly CM
    Cell Mol Immunol; 2010 Mar; 7(2):123-32. PubMed ID: 20140007
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Association of suppression of extracellular signal-regulated kinase phosphorylation by epigallocatechin gallate with the reduction of matrix metalloproteinase activities in human fibrosarcoma HT1080 cells.
    Maeda-Yamamoto M; Suzuki N; Sawai Y; Miyase T; Sano M; Hashimoto-Ohta A; Isemura M
    J Agric Food Chem; 2003 Mar; 51(7):1858-63. PubMed ID: 12643642
    [TBL] [Abstract][Full Text] [Related]  

  • 32. The green tea compound, (-)-epigallocatechin-3-gallate downregulates N-cadherin and suppresses migration of bladder carcinoma cells.
    Rieger-Christ KM; Hanley R; Lodowsky C; Bernier T; Vemulapalli P; Roth M; Kim J; Yee AS; Le SM; Marie PJ; Libertino JA; Summerhayes IC
    J Cell Biochem; 2007 Oct; 102(2):377-88. PubMed ID: 17348027
    [TBL] [Abstract][Full Text] [Related]  

  • 33. EGCG, a major component of green tea, inhibits tumour growth by inhibiting VEGF induction in human colon carcinoma cells.
    Jung YD; Kim MS; Shin BA; Chay KO; Ahn BW; Liu W; Bucana CD; Gallick GE; Ellis LM
    Br J Cancer; 2001 Mar; 84(6):844-50. PubMed ID: 11259102
    [TBL] [Abstract][Full Text] [Related]  

  • 34. (--)-epigallocatechin gallate enhances prostaglandin F2alpha-induced VEGF synthesis via upregulating SAPK/JNK activation in osteoblasts.
    Tokuda H; Takai S; Matsushima-Nishiwaki R; Akamatsu S; Hanai Y; Hosoi T; Harada A; Ohta T; Kozawa O
    J Cell Biochem; 2007 Apr; 100(5):1146-53. PubMed ID: 17031857
    [TBL] [Abstract][Full Text] [Related]  

  • 35. PI3K/AKT/mTOR signaling is involved in (-)-epigallocatechin-3-gallate-induced apoptosis of human pancreatic carcinoma cells.
    Liu S; Wang XJ; Liu Y; Cui YF
    Am J Chin Med; 2013; 41(3):629-42. PubMed ID: 23711146
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Discovery of novel anticancer therapeutics targeting the PI3K/Akt/mTOR pathway.
    Maira SM; Furet P; Stauffer F
    Future Med Chem; 2009 Apr; 1(1):137-55. PubMed ID: 21426073
    [TBL] [Abstract][Full Text] [Related]  

  • 37. A new epigallocatechin gallate derivative isolated from Anhua dark tea sensitizes the chemosensitivity of gefitinib via the suppression of PI3K/mTOR and epithelial-mesenchymal transition.
    Liu J; Zhong T; Yi P; Fan C; Zhang Z; Liang G; Xu Y; Fan Y
    Fitoterapia; 2020 Jun; 143():104590. PubMed ID: 32272164
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Inhibition of tumor promoter-induced activator protein 1 activation and cell transformation by tea polyphenols, (-)-epigallocatechin gallate, and theaflavins.
    Dong Z; Ma W; Huang C; Yang CS
    Cancer Res; 1997 Oct; 57(19):4414-9. PubMed ID: 9331105
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Epigallocatechin-3-gallate-induced stress signals in HT-29 human colon adenocarcinoma cells.
    Chen C; Shen G; Hebbar V; Hu R; Owuor ED; Kong AN
    Carcinogenesis; 2003 Aug; 24(8):1369-78. PubMed ID: 12819184
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Development of LanthaScreen cellular assays for key components within the PI3K/AKT/mTOR pathway.
    Carlson CB; Robers MB; Vogel KW; Machleidt T
    J Biomol Screen; 2009 Feb; 14(2):121-32. PubMed ID: 19196698
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 20.