These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

573 related articles for article (PubMed ID: 21300751)

  • 1. Early activation of mTORC1 signalling in response to mechanical overload is independent of phosphoinositide 3-kinase/Akt signalling.
    Miyazaki M; McCarthy JJ; Fedele MJ; Esser KA
    J Physiol; 2011 Apr; 589(Pt 7):1831-46. PubMed ID: 21300751
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Protein kinase C and P2Y12 take center stage in thrombin-mediated activation of mammalian target of rapamycin complex 1 in human platelets.
    Moore SF; Hunter RW; Hers I
    J Thromb Haemost; 2014 May; 12(5):748-60. PubMed ID: 24612393
    [TBL] [Abstract][Full Text] [Related]  

  • 3. No role for early IGF-1 signalling in stimulating acute 'muscle building' responses.
    Burd NA; West DW; Camera DM; Breen L
    J Physiol; 2011 Jun; 589(Pt 11):2667-8. PubMed ID: 21632529
    [No Abstract]   [Full Text] [Related]  

  • 4. ERK and Akt signaling pathways function through parallel mechanisms to promote mTORC1 signaling.
    Winter JN; Jefferson LS; Kimball SR
    Am J Physiol Cell Physiol; 2011 May; 300(5):C1172-80. PubMed ID: 21289294
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Receptor-recognized α₂-macroglobulin binds to cell surface-associated GRP78 and activates mTORC1 and mTORC2 signaling in prostate cancer cells.
    Misra UK; Pizzo SV
    PLoS One; 2012; 7(12):e51735. PubMed ID: 23272152
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ran is a potential therapeutic target for cancer cells with molecular changes associated with activation of the PI3K/Akt/mTORC1 and Ras/MEK/ERK pathways.
    Yuen HF; Chan KK; Grills C; Murray JT; Platt-Higgins A; Eldin OS; O'Byrne K; Janne P; Fennell DA; Johnston PG; Rudland PS; El-Tanani M
    Clin Cancer Res; 2012 Jan; 18(2):380-91. PubMed ID: 22090358
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Alkaline intracellular pH (pHi) increases PI3K activity to promote mTORC1 and mTORC2 signaling and function during growth factor limitation.
    Kazyken D; Lentz SI; Wadley M; Fingar DC
    J Biol Chem; 2023 Sep; 299(9):105097. PubMed ID: 37507012
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Constitutive activation of CaMKKα signaling is sufficient but not necessary for mTORC1 activation and growth in mouse skeletal muscle.
    Ferey JL; Brault JJ; Smith CA; Witczak CA
    Am J Physiol Endocrinol Metab; 2014 Oct; 307(8):E686-94. PubMed ID: 25159322
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Impact of oncogenic driver mutations on feedback between the PI3K and MEK pathways in cancer cells.
    Yuen HF; Abramczyk O; Montgomery G; Chan KK; Huang YH; Sasazuki T; Shirasawa S; Gopesh S; Chan KW; Fennell D; Janne P; El-Tanani M; Murray JT
    Biosci Rep; 2012 Aug; 32(4):413-22. PubMed ID: 22668349
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Insulin stimulates adipogenesis through the Akt-TSC2-mTORC1 pathway.
    Zhang HH; Huang J; Düvel K; Boback B; Wu S; Squillace RM; Wu CL; Manning BD
    PLoS One; 2009 Jul; 4(7):e6189. PubMed ID: 19593385
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Human chorionic gonadotropin stimulates theca-interstitial cell proliferation and cell cycle regulatory proteins by a cAMP-dependent activation of AKT/mTORC1 signaling pathway.
    Palaniappan M; Menon KM
    Mol Endocrinol; 2010 Sep; 24(9):1782-93. PubMed ID: 20660299
    [TBL] [Abstract][Full Text] [Related]  

  • 12. mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling.
    Julien LA; Carriere A; Moreau J; Roux PP
    Mol Cell Biol; 2010 Feb; 30(4):908-21. PubMed ID: 19995915
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Serine 302 Phosphorylation of Mouse Insulin Receptor Substrate 1 (IRS1) Is Dispensable for Normal Insulin Signaling and Feedback Regulation by Hepatic S6 Kinase.
    Copps KD; Hançer NJ; Qiu W; White MF
    J Biol Chem; 2016 Apr; 291(16):8602-17. PubMed ID: 26846849
    [TBL] [Abstract][Full Text] [Related]  

  • 14. TGFβ-stimulated microRNA-21 utilizes PTEN to orchestrate AKT/mTORC1 signaling for mesangial cell hypertrophy and matrix expansion.
    Dey N; Ghosh-Choudhury N; Kasinath BS; Choudhury GG
    PLoS One; 2012; 7(8):e42316. PubMed ID: 22879939
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Electrostimulation during hindlimb unloading modulates PI3K-AKT downstream targets without preventing soleus atrophy and restores slow phenotype through ERK.
    Dupont E; Cieniewski-Bernard C; Bastide B; Stevens L
    Am J Physiol Regul Integr Comp Physiol; 2011 Feb; 300(2):R408-17. PubMed ID: 21106911
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Renal tumours in a Tsc2(+/-) mouse model do not show feedback inhibition of Akt and are effectively prevented by rapamycin.
    Yang J; Kalogerou M; Samsel PA; Zhang Y; Griffiths DF; Gallacher J; Sampson JR; Shen MH
    Oncogene; 2015 Feb; 34(7):922-31. PubMed ID: 24632604
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ubiquitin E3 ligase Atrogin-1 protein is regulated via the rapamycin-sensitive mTOR-S6K1 signaling pathway in C2C12 muscle cells.
    Nishimura Y; Chunthorng-Orn J; Lord S; Musa I; Dawson P; Holm L; Lai YC
    Am J Physiol Cell Physiol; 2022 Jul; 323(1):C215-C225. PubMed ID: 35704697
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Activation of AMPK/TSC2/PLD by alcohol regulates mTORC1 and mTORC2 assembly in C2C12 myocytes.
    Hong-Brown LQ; Brown CR; Navaratnarajah M; Lang CH
    Alcohol Clin Exp Res; 2013 Nov; 37(11):1849-61. PubMed ID: 23895284
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Akt-dependent activation of mTORC1 complex involves phosphorylation of mTOR (mammalian target of rapamycin) by IκB kinase α (IKKα).
    Dan HC; Ebbs A; Pasparakis M; Van Dyke T; Basseres DS; Baldwin AS
    J Biol Chem; 2014 Sep; 289(36):25227-40. PubMed ID: 24990947
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pharmacological inhibition of S6K1 increases glucose metabolism and Akt signalling in vitro and in diet-induced obese mice.
    Shum M; Bellmann K; St-Pierre P; Marette A
    Diabetologia; 2016 Mar; 59(3):592-603. PubMed ID: 26733005
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 29.