181 related articles for article (PubMed ID: 21302359)
1. Synthesis, receptor binding, and CNS pharmacological studies of new thyrotropin-releasing hormone (TRH) analogues.
Monga V; Meena CL; Rajput S; Pawar C; Sharma SS; Lu X; Gershengorn MC; Jain R
ChemMedChem; 2011 Mar; 6(3):531-43. PubMed ID: 21302359
[TBL] [Abstract][Full Text] [Related]
2. Synthesis, receptor binding, and activation studies of N(1)-alkyl-L-histidine containing thyrotropin-releasing hormone (TRH) analogues.
Kaur N; Monga V; Josan JS; Lu X; Gershengorn MC; Jain R
Bioorg Med Chem; 2006 Sep; 14(17):5981-8. PubMed ID: 16735122
[TBL] [Abstract][Full Text] [Related]
3. Thyrotropin-releasing hormone (TRH) analogues that exhibit selectivity to TRH receptor subtype 2.
Kaur N; Lu X; Gershengorn MC; Jain R
J Med Chem; 2005 Sep; 48(19):6162-5. PubMed ID: 16162016
[TBL] [Abstract][Full Text] [Related]
4. Modifications of the pyroglutamic acid and histidine residues in thyrotropin-releasing hormone (TRH) yield analogs with selectivity for TRH receptor type 2 over type 1.
Kaur N; Monga V; Lu X; Gershengorn MC; Jain R
Bioorg Med Chem; 2007 Jan; 15(1):433-43. PubMed ID: 17035026
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and biology of ring-modified l-Histidine containing thyrotropin-releasing hormone (TRH) analogues.
Meena CL; Thakur A; Nandekar PP; Sharma SS; Sangamwar AT; Jain R
Eur J Med Chem; 2016 Mar; 111():72-83. PubMed ID: 26854379
[TBL] [Abstract][Full Text] [Related]
6. Synthesis of CNS active thyrotropin-releasing hormone (TRH)-like peptides: Biological evaluation and effect on cognitive impairment induced by cerebral ischemia in mice.
Meena CL; Thakur A; Nandekar PP; Sangamwar AT; Sharma SS; Jain R
Bioorg Med Chem; 2015 Sep; 23(17):5641-53. PubMed ID: 26216015
[TBL] [Abstract][Full Text] [Related]
7. Selectivity-based QSAR approach for screening and evaluation of TRH analogs for TRH-R1 and TRH-R2 receptors subtypes.
Kadam RU; Chavan AG; Monga V; Kaur N; Jain R; Roy N
J Mol Graph Model; 2008 Oct; 27(3):309-20. PubMed ID: 18595758
[TBL] [Abstract][Full Text] [Related]
8. Thyrotropin-releasing hormone receptors -- similarities and differences.
Sun Y; Lu X; Gershengorn MC
J Mol Endocrinol; 2003 Apr; 30(2):87-97. PubMed ID: 12683933
[TBL] [Abstract][Full Text] [Related]
9. Thyrotropin-releasing hormone receptor type 1 (TRH-R1), not TRH-R2, primarily mediates taltirelin actions in the CNS of mice.
Thirunarayanan N; Nir EA; Raaka BM; Gershengorn MC
Neuropsychopharmacology; 2013 May; 38(6):950-6. PubMed ID: 23303050
[TBL] [Abstract][Full Text] [Related]
10. Chemistry and biology of thyrotropin-releasing hormone (TRH) and its analogs.
Monga V; Meena CL; Kaur N; Jain R
Curr Med Chem; 2008; 15(26):2718-33. PubMed ID: 18991632
[TBL] [Abstract][Full Text] [Related]
11. Discovery of a low affinity thyrotropin-releasing hormone (TRH)-like peptide that exhibits potent inhibition of scopolamine-induced memory impairment in mice.
Meena CL; Ingole S; Rajpoot S; Thakur A; Nandeker PP; Sangamwar AT; Sharma SS; Jain R
RSC Adv; 2015 Jun; 5():56872-56884. PubMed ID: 26191403
[TBL] [Abstract][Full Text] [Related]
12. Low affinity analogs of thyrotropin-releasing hormone are super-agonists.
Engel S; Neumann S; Kaur N; Monga V; Jain R; Northup J; Gershengorn MC
J Biol Chem; 2006 May; 281(19):13103-13109. PubMed ID: 16551618
[TBL] [Abstract][Full Text] [Related]
13. Design, synthesis, and biological evaluation of novel, centrally-acting thyrotropin-releasing hormone analogues.
Prokai-Tatrai K; Perjési P; Zharikova AD; Li X; Prokai L
Bioorg Med Chem Lett; 2002 Aug; 12(16):2171-4. PubMed ID: 12127530
[TBL] [Abstract][Full Text] [Related]
14. TRH-R2 exhibits similar binding and acute signaling but distinct regulation and anatomic distribution compared with TRH-R1.
O'Dowd BF; Lee DK; Huang W; Nguyen T; Cheng R; Liu Y; Wang B; Gershengorn MC; George SR
Mol Endocrinol; 2000 Jan; 14(1):183-93. PubMed ID: 10628757
[TBL] [Abstract][Full Text] [Related]
15. Antiepileptic potential and behavioral profile of L-pGlu-(2-propyl)-L-His-L-ProNH2, a newer thyrotropin-releasing hormone analog.
Rajput SK; Krishnamoorthy S; Pawar C; Kaur N; Monga V; Meena CL; Jain R; Sharma SS
Epilepsy Behav; 2009 Jan; 14(1):48-53. PubMed ID: 18952198
[TBL] [Abstract][Full Text] [Related]
16. Persistent signaling by thyrotropin-releasing hormone receptors correlates with G-protein and receptor levels.
Boutin A; Allen MD; Neumann S; Gershengorn MC
FASEB J; 2012 Aug; 26(8):3473-82. PubMed ID: 22593547
[TBL] [Abstract][Full Text] [Related]
17. First-in-class thyrotropin-releasing hormone (TRH)-based compound binds to a pharmacologically distinct TRH receptor subtype in human brain and is effective in neurodegenerative models.
Kelly JA; Boyle NT; Cole N; Slator GR; Colivicchi MA; Stefanini C; Gobbo OL; Scalabrino GA; Ryan SM; Elamin M; Walsh C; Vajda A; Goggin MM; Campbell M; Mash DC; O'Mara SM; Brayden DJ; Callanan JJ; Tipton KF; Della Corte L; Hunter J; O'Boyle KM; Williams CH; Hardiman O
Neuropharmacology; 2015 Feb; 89():193-203. PubMed ID: 25281210
[TBL] [Abstract][Full Text] [Related]
18. Involvement of thyrotropin-releasing hormone (TRH) neural system of the brain in pentylenetetrazol-induced seizures.
Ogawa N; Hirose Y; Mori A; Kajita S; Sato M
Regul Pept; 1985 Nov; 12(3):249-56. PubMed ID: 3001843
[TBL] [Abstract][Full Text] [Related]
19. Thyrotropin-releasing hormone (TRH) and its beta-alanine analogue: potentiation of the anticonvulsant potency of phenobarbital in mice.
Nemeroff CB; Prange AJ; Bissette G; Breese GR; Lipton MA
Psychopharmacol Commun; 1975; 1(3):305-17. PubMed ID: 817374
[TBL] [Abstract][Full Text] [Related]
20. Changes in brain thyrotropin-releasing hormone (TRH) of seizure-prone El mice.
Yamashita K; Mori A; Otsuki S
Exp Neurol; 1990 Apr; 108(1):71-5. PubMed ID: 2156726
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]