231 related articles for article (PubMed ID: 21304979)
1. Mevalonate cascade regulation of airway mesenchymal cell autophagy and apoptosis: a dual role for p53.
Ghavami S; Mutawe MM; Sharma P; Yeganeh B; McNeill KD; Klonisch T; Unruh H; Kashani HH; Schaafsma D; Los M; Halayko AJ
PLoS One; 2011 Jan; 6(1):e16523. PubMed ID: 21304979
[TBL] [Abstract][Full Text] [Related]
2. Airway mesenchymal cell death by mevalonate cascade inhibition: integration of autophagy, unfolded protein response and apoptosis focusing on Bcl2 family proteins.
Ghavami S; Sharma P; Yeganeh B; Ojo OO; Jha A; Mutawe MM; Kashani HH; Los MJ; Klonisch T; Unruh H; Halayko AJ
Biochim Biophys Acta; 2014 Jul; 1843(7):1259-71. PubMed ID: 24637330
[TBL] [Abstract][Full Text] [Related]
3. Statin-triggered cell death in primary human lung mesenchymal cells involves p53-PUMA and release of Smac and Omi but not cytochrome c.
Ghavami S; Mutawe MM; Hauff K; Stelmack GL; Schaafsma D; Sharma P; McNeill KD; Hynes TS; Kung SK; Unruh H; Klonisch T; Hatch GM; Los M; Halayko AJ
Biochim Biophys Acta; 2010 Apr; 1803(4):452-67. PubMed ID: 20045437
[TBL] [Abstract][Full Text] [Related]
4. Geranylgeranyl transferase 1 modulates autophagy and apoptosis in human airway smooth muscle.
Ghavami S; Mutawe MM; Schaafsma D; Yeganeh B; Unruh H; Klonisch T; Halayko AJ
Am J Physiol Lung Cell Mol Physiol; 2012 Feb; 302(4):L420-8. PubMed ID: 22160308
[TBL] [Abstract][Full Text] [Related]
5. Apoptosis, autophagy and ER stress in mevalonate cascade inhibition-induced cell death of human atrial fibroblasts.
Ghavami S; Yeganeh B; Stelmack GL; Kashani HH; Sharma P; Cunnington R; Rattan S; Bathe K; Klonisch T; Dixon IM; Freed DH; Halayko AJ
Cell Death Dis; 2012 Jun; 3(6):e330. PubMed ID: 22717585
[TBL] [Abstract][Full Text] [Related]
6. p53-Dependent PUMA to DRAM antagonistic interplay as a key molecular switch in cell-fate decision in normal/high glucose conditions.
Garufi A; Pistritto G; Baldari S; Toietta G; Cirone M; D'Orazi G
J Exp Clin Cancer Res; 2017 Sep; 36(1):126. PubMed ID: 28893313
[TBL] [Abstract][Full Text] [Related]
7. Inhibition of AMPK-dependent autophagy enhances in vitro antiglioma effect of simvastatin.
Misirkic M; Janjetovic K; Vucicevic L; Tovilovic G; Ristic B; Vilimanovich U; Harhaji-Trajkovic L; Sumarac-Dumanovic M; Micic D; Bumbasirevic V; Trajkovic V
Pharmacol Res; 2012 Jan; 65(1):111-9. PubMed ID: 21871960
[TBL] [Abstract][Full Text] [Related]
8. Simvastatin alleviates airway inflammation and remodelling through up-regulation of autophagy in mouse models of asthma.
Gu W; Cui R; Ding T; Li X; Peng J; Xu W; Han F; Guo X
Respirology; 2017 Apr; 22(3):533-541. PubMed ID: 27782356
[TBL] [Abstract][Full Text] [Related]
9. 3-Hydroxy-3-methyl-glutaryl coenzyme A reductase inhibitors, atorvastatin and simvastatin, induce apoptosis of vascular smooth muscle cells by downregulation of Bcl-2 expression and Rho A prenylation.
Blanco-Colio LM; Villa A; Ortego M; Hernández-Presa MA; Pascual A; Plaza JJ; Egido J
Atherosclerosis; 2002 Mar; 161(1):17-26. PubMed ID: 11882313
[TBL] [Abstract][Full Text] [Related]
10. Mevalonate Cascade Inhibition by Simvastatin Induces the Intrinsic Apoptosis Pathway via Depletion of Isoprenoids in Tumor Cells.
Alizadeh J; Zeki AA; Mirzaei N; Tewary S; Rezaei Moghadam A; Glogowska A; Nagakannan P; Eftekharpour E; Wiechec E; Gordon JW; Xu FY; Field JT; Yoneda KY; Kenyon NJ; Hashemi M; Hatch GM; Hombach-Klonisch S; Klonisch T; Ghavami S
Sci Rep; 2017 Mar; 7():44841. PubMed ID: 28344327
[TBL] [Abstract][Full Text] [Related]
11. Preclinical evaluation of statins as a treatment for ovarian cancer.
Robinson E; Nandi M; Wilkinson LL; Arrowsmith DM; Curtis AD; Richardson A
Gynecol Oncol; 2013 May; 129(2):417-24. PubMed ID: 23402903
[TBL] [Abstract][Full Text] [Related]
12. Mutant p53 murine oviductal epithelial cells induce progression of high-grade serous carcinoma and are most sensitive to simvastatin therapy in vitro and in vivo.
Pereira M; Glogova A; Haagsma J; Stewart J; Shepherd TG; Petrik J
J Ovarian Res; 2023 Nov; 16(1):218. PubMed ID: 37986175
[TBL] [Abstract][Full Text] [Related]
13. p53 induction contributes to excitotoxic neuronal death in rat striatum through apoptotic and autophagic mechanisms.
Wang Y; Dong XX; Cao Y; Liang ZQ; Han R; Wu JC; Gu ZL; Qin ZH
Eur J Neurosci; 2009 Dec; 30(12):2258-70. PubMed ID: 20092569
[TBL] [Abstract][Full Text] [Related]
14. Simvastatin induced HCT116 colorectal cancer cell apoptosis through p38MAPK-p53-survivin signaling cascade.
Chang HL; Chen CY; Hsu YF; Kuo WS; Ou G; Chiu PT; Huang YH; Hsu MJ
Biochim Biophys Acta; 2013 Aug; 1830(8):4053-64. PubMed ID: 23583370
[TBL] [Abstract][Full Text] [Related]
15. Statin-induced breast cancer cell death: role of inducible nitric oxide and arginase-dependent pathways.
Kotamraju S; Williams CL; Kalyanaraman B
Cancer Res; 2007 Aug; 67(15):7386-94. PubMed ID: 17671209
[TBL] [Abstract][Full Text] [Related]
16. Geranylgeranyl-pyrophosphate, an isoprenoid of mevalonate cascade, is a critical compound for rat primary cultured cortical neurons to protect the cell death induced by 3-hydroxy-3-methylglutaryl-CoA reductase inhibition.
Tanaka T; Tatsuno I; Uchida D; Moroo I; Morio H; Nakamura S; Noguchi Y; Yasuda T; Kitagawa M; Saito Y; Hirai A
J Neurosci; 2000 Apr; 20(8):2852-9. PubMed ID: 10751437
[TBL] [Abstract][Full Text] [Related]
17. p53 mediates mitochondria dysfunction-triggered autophagy activation and cell death in rat striatum.
Zhang XD; Wang Y; Wang Y; Zhang X; Han R; Wu JC; Liang ZQ; Gu ZL; Han F; Fukunaga K; Qin ZH
Autophagy; 2009 Apr; 5(3):339-50. PubMed ID: 19305162
[TBL] [Abstract][Full Text] [Related]
18. Lipophilic but not hydrophilic statins selectively induce cell death in gynaecological cancers expressing high levels of HMGCoA reductase.
Kato S; Smalley S; Sadarangani A; Chen-Lin K; Oliva B; Brañes J; Carvajal J; Gejman R; Owen GI; Cuello M
J Cell Mol Med; 2010 May; 14(5):1180-93. PubMed ID: 19432822
[TBL] [Abstract][Full Text] [Related]
19. Autophagy-mediated cytoplasmic accumulation of p53 leads to apoptosis through DRAM-BAX in cadmium-exposed human proximal tubular cells.
Lee HY; Oh SH
Biochem Biophys Res Commun; 2021 Jan; 534():128-133. PubMed ID: 33321290
[TBL] [Abstract][Full Text] [Related]
20. Blocking NF-κB nuclear translocation leads to p53-related autophagy activation and cell apoptosis.
Zhu BS; Xing CG; Lin F; Fan XQ; Zhao K; Qin ZH
World J Gastroenterol; 2011 Jan; 17(4):478-87. PubMed ID: 21274377
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
