BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

310 related articles for article (PubMed ID: 21307248)

  • 1. Spinal phosphinositide 3-kinase-Akt-mammalian target of rapamycin signaling cascades in inflammation-induced hyperalgesia.
    Xu Q; Fitzsimmons B; Steinauer J; O'Neill A; Newton AC; Hua XY; Yaksh TL
    J Neurosci; 2011 Feb; 31(6):2113-24. PubMed ID: 21307248
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phosphatidylinositol 3-kinase activates ERK in primary sensory neurons and mediates inflammatory heat hyperalgesia through TRPV1 sensitization.
    Zhuang ZY; Xu H; Clapham DE; Ji RR
    J Neurosci; 2004 Sep; 24(38):8300-9. PubMed ID: 15385613
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activation of phosphatidylinositol 3-kinase and protein kinase B/Akt in dorsal root ganglia and spinal cord contributes to the neuropathic pain induced by spinal nerve ligation in rats.
    Xu JT; Tu HY; Xin WJ; Liu XG; Zhang GH; Zhai CH
    Exp Neurol; 2007 Aug; 206(2):269-79. PubMed ID: 17628541
    [TBL] [Abstract][Full Text] [Related]  

  • 4. mTOR and its downstream pathway are activated in the dorsal root ganglion and spinal cord after peripheral inflammation, but not after nerve injury.
    Liang L; Tao B; Fan L; Yaster M; Zhang Y; Tao YX
    Brain Res; 2013 Jun; 1513():17-25. PubMed ID: 23583278
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Spinal phospholipase A2 in inflammatory hyperalgesia: role of the small, secretory phospholipase A2.
    Svensson CI; Lucas KK; Hua XY; Powell HC; Dennis EA; Yaksh TL
    Neuroscience; 2005; 133(2):543-53. PubMed ID: 15885922
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of spinal constitutive NOS-2 by 1400W attenuates tissue injury and inflammation-induced hyperalgesia and spinal p38 activation.
    Tang Q; Svensson CI; Fitzsimmons B; Webb M; Yaksh TL; Hua XY
    Eur J Neurosci; 2007 May; 25(10):2964-72. PubMed ID: 17561811
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The c-Jun N-terminal kinase 1 (JNK1) in spinal astrocytes is required for the maintenance of bilateral mechanical allodynia under a persistent inflammatory pain condition.
    Gao YJ; Xu ZZ; Liu YC; Wen YR; Decosterd I; Ji RR
    Pain; 2010 Feb; 148(2):309-319. PubMed ID: 20022176
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PI3K contributed to modulation of spinal nociceptive information related to ephrinBs/EphBs.
    Yu LN; Zhou XL; Yu J; Huang H; Jiang LS; Zhang FJ; Cao JL; Yan M
    PLoS One; 2012; 7(8):e40930. PubMed ID: 22879882
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Regulation of the phosphatidylinositol 3-kinase, Akt/protein kinase B, FRAP/mammalian target of rapamycin, and ribosomal S6 kinase 1 signaling pathways by thyroid-stimulating hormone (TSH) and stimulating type TSH receptor antibodies in the thyroid gland.
    Suh JM; Song JH; Kim DW; Kim H; Chung HK; Hwang JH; Kim JM; Hwang ES; Chung J; Han JH; Cho BY; Ro HK; Shong M
    J Biol Chem; 2003 Jun; 278(24):21960-71. PubMed ID: 12668683
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effects of inhibiting the PI3K/Akt/mTOR signaling pathway on the pain of sciatic endometriosis in a rat model.
    Liu Y; Qin X; Lu X; Jiang J
    Can J Physiol Pharmacol; 2019 Oct; 97(10):963-970. PubMed ID: 31461309
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Blocking Mammalian Target of Rapamycin (mTOR) Alleviates Neuropathic Pain Induced by Chemotherapeutic Bortezomib.
    Duan Z; Li J; Pang X; Wang H; Su Z
    Cell Physiol Biochem; 2018; 48(1):54-62. PubMed ID: 29996117
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Neuroinflammation and central PI3K/Akt/mTOR signal pathway contribute to bone cancer pain.
    Zhang J; Wang L; Wang H; Su Z; Pang X
    Mol Pain; 2019; 15():1744806919830240. PubMed ID: 30717619
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Involvement of phosphatidylinositol-3 kinase/Akt/mammalian target of rapamycin/peroxisome proliferator-activated receptor γ pathway for induction and maintenance of neuropathic pain.
    Kondo D; Saegusa H; Tanabe T
    Biochem Biophys Res Commun; 2018 May; 499(2):253-259. PubMed ID: 29567475
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Opioid receptor-triggered spinal mTORC1 activation contributes to morphine tolerance and hyperalgesia.
    Xu JT; Zhao JY; Zhao X; Ligons D; Tiwari V; Atianjoh FE; Lee CY; Liang L; Zang W; Njoku D; Raja SN; Yaster M; Tao YX
    J Clin Invest; 2014 Feb; 124(2):592-603. PubMed ID: 24382350
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Activation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway is required for metabotropic glutamate receptor-dependent long-term depression.
    Hou L; Klann E
    J Neurosci; 2004 Jul; 24(28):6352-61. PubMed ID: 15254091
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Activation of p38 mitogen-activated protein kinase in spinal microglia is a critical link in inflammation-induced spinal pain processing.
    Svensson CI; Marsala M; Westerlund A; Calcutt NA; Campana WM; Freshwater JD; Catalano R; Feng Y; Protter AA; Scott B; Yaksh TL
    J Neurochem; 2003 Sep; 86(6):1534-44. PubMed ID: 12950462
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mammalian target of rapamycin in spinal cord neurons mediates hypersensitivity induced by peripheral inflammation.
    Norsted Gregory E; Codeluppi S; Gregory JA; Steinauer J; Svensson CI
    Neuroscience; 2010 Sep; 169(3):1392-402. PubMed ID: 20538043
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Electroacupuncture inhibits phosphorylation of spinal phosphatidylinositol 3-kinase/Akt in a carrageenan-induced inflammatory rat model.
    Kim HN; Kim YR; Jang JY; Shin HK; Choi BT
    Brain Res Bull; 2012 Feb; 87(2-3):199-204. PubMed ID: 22155296
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The inhibition of spinal synaptic plasticity mediated by activation of AMP-activated protein kinase signaling alleviates the acute pain induced by oxaliplatin.
    Ling YZ; Li ZY; Ou-Yang HD; Ma C; Wu SL; Wei JY; Ding HH; Zhang XL; Liu M; Liu CC; Huang ZZ; Xin WJ
    Exp Neurol; 2017 Feb; 288():85-93. PubMed ID: 27856287
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Spinal cord mechanisms mediating behavioral hyperalgesia induced by neurokinin-1 tachykinin receptor activation in the rostral ventromedial medulla.
    Lagraize SC; Guo W; Yang K; Wei F; Ren K; Dubner R
    Neuroscience; 2010 Dec; 171(4):1341-56. PubMed ID: 20888891
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.