370 related articles for article (PubMed ID: 21316481)
1. von Hippel-Lindau protein adjusts oxygen sensing of the FIH asparaginyl hydroxylase.
Li SH; Chun YS; Lim JH; Huang LE; Park JW
Int J Biochem Cell Biol; 2011 May; 43(5):795-804. PubMed ID: 21316481
[TBL] [Abstract][Full Text] [Related]
2. A dynamic model of the hypoxia-inducible factor 1α (HIF-1α) network.
Nguyen LK; Cavadas MA; Scholz CC; Fitzpatrick SF; Bruning U; Cummins EP; Tambuwala MM; Manresa MC; Kholodenko BN; Taylor CT; Cheong A
J Cell Sci; 2013 Mar; 126(Pt 6):1454-63. PubMed ID: 23390316
[TBL] [Abstract][Full Text] [Related]
3. Ferritin heavy chain controls the HIF-driven hypoxic response by activating the asparaginyl hydroxylase FIH.
Jin P; Kang J; Lee MK; Park JW
Biochem Biophys Res Commun; 2018 May; 499(3):475-481. PubMed ID: 29580991
[TBL] [Abstract][Full Text] [Related]
4. Immunoexpression patterns for Hypoxia-inducible Factor-1α and von Hippel-Lindau protein, in relation to Hsp90, of human brain tumors.
Assimakopoulou M; Androutsopoulou C; Zolota V; Matsoukas J
Histol Histopathol; 2016 May; 31(5):535-46. PubMed ID: 26592496
[TBL] [Abstract][Full Text] [Related]
5. Inhibitor of nuclear factor-kappaB alpha derepresses hypoxia-inducible factor-1 during moderate hypoxia by sequestering factor inhibiting hypoxia-inducible factor from hypoxia-inducible factor 1alpha.
Shin DH; Li SH; Yang SW; Lee BL; Lee MK; Park JW
FEBS J; 2009 Jul; 276(13):3470-80. PubMed ID: 19456861
[TBL] [Abstract][Full Text] [Related]
6. Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function.
Krieg M; Haas R; Brauch H; Acker T; Flamme I; Plate KH
Oncogene; 2000 Nov; 19(48):5435-43. PubMed ID: 11114720
[TBL] [Abstract][Full Text] [Related]
7. FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity.
Mahon PC; Hirota K; Semenza GL
Genes Dev; 2001 Oct; 15(20):2675-86. PubMed ID: 11641274
[TBL] [Abstract][Full Text] [Related]
8. The Factor Inhibiting HIF Asparaginyl Hydroxylase Regulates Oxidative Metabolism and Accelerates Metabolic Adaptation to Hypoxia.
Sim J; Cowburn AS; Palazon A; Madhu B; Tyrakis PA; Macías D; Bargiela DM; Pietsch S; Gralla M; Evans CE; Kittipassorn T; Chey YCJ; Branco CM; Rundqvist H; Peet DJ; Johnson RS
Cell Metab; 2018 Apr; 27(4):898-913.e7. PubMed ID: 29617647
[TBL] [Abstract][Full Text] [Related]
9. Inositol Polyphosphate Multikinase Inhibits Angiogenesis via Inositol Pentakisphosphate-Induced HIF-1α Degradation.
Fu C; Tyagi R; Chin AC; Rojas T; Li RJ; Guha P; Bernstein IA; Rao F; Xu R; Cha JY; Xu J; Snowman AM; Semenza GL; Snyder SH
Circ Res; 2018 Feb; 122(3):457-472. PubMed ID: 29279301
[TBL] [Abstract][Full Text] [Related]
10. Regulation of HIF by the von Hippel-Lindau tumour suppressor: implications for cellular oxygen sensing.
Mole DR; Maxwell PH; Pugh CW; Ratcliffe PJ
IUBMB Life; 2001 Jul; 52(1-2):43-7. PubMed ID: 11795592
[TBL] [Abstract][Full Text] [Related]
11. Nuclear-cytoplasmatic shuttling of proteins in control of cellular oxygen sensing.
Depping R; Jelkmann W; Kosyna FK
J Mol Med (Berl); 2015 Jun; 93(6):599-608. PubMed ID: 25809665
[TBL] [Abstract][Full Text] [Related]
12. Nutlin-3, an Hdm2 antagonist, inhibits tumor adaptation to hypoxia by stimulating the FIH-mediated inactivation of HIF-1alpha.
Lee YM; Lim JH; Chun YS; Moon HE; Lee MK; Huang LE; Park JW
Carcinogenesis; 2009 Oct; 30(10):1768-75. PubMed ID: 19696166
[TBL] [Abstract][Full Text] [Related]
13. Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway.
Carroll VA; Ashcroft M
Cancer Res; 2006 Jun; 66(12):6264-70. PubMed ID: 16778202
[TBL] [Abstract][Full Text] [Related]
14. Hypoxia-inducible factor 1α mediates the down-regulation of superoxide dismutase 2 in von Hippel-Lindau deficient renal clear cell carcinoma.
Gao YH; Li CX; Shen SM; Li H; Chen GQ; Wei Q; Wang LS
Biochem Biophys Res Commun; 2013 May; 435(1):46-51. PubMed ID: 23611775
[TBL] [Abstract][Full Text] [Related]
15. Proline hydroxylation at different sites in hypoxia-inducible factor 1α modulates its interactions with the von Hippel-Lindau tumor suppressor protein.
Qian H; Zou Y; Tang Y; Gong Y; Qian Z; Wei G; Zhang Q
Phys Chem Chem Phys; 2018 Jul; 20(27):18756-18765. PubMed ID: 29961792
[TBL] [Abstract][Full Text] [Related]
16. Minocycline accelerates hypoxia-inducible factor-1 alpha degradation and inhibits hypoxia-induced neovasculogenesis through prolyl hydroxylase, von Hippel-Lindau-dependent pathway.
Li CH; Liao PL; Yang YT; Huang SH; Lin CH; Cheng YW; Kang JJ
Arch Toxicol; 2014 Mar; 88(3):659-71. PubMed ID: 24292262
[TBL] [Abstract][Full Text] [Related]
17. Alternative regulation of HIF-1α stability through Phosphorylation on Ser451.
Han HJ; Saeidi S; Kim SJ; Piao JY; Lim S; Guillen-Quispe YN; Choi BY; Surh YJ
Biochem Biophys Res Commun; 2021 Mar; 545():150-156. PubMed ID: 33550096
[TBL] [Abstract][Full Text] [Related]
18. Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases.
Koivunen P; Hirsilä M; Günzler V; Kivirikko KI; Myllyharju J
J Biol Chem; 2004 Mar; 279(11):9899-904. PubMed ID: 14701857
[TBL] [Abstract][Full Text] [Related]
19. VBP1 represses cancer metastasis by enhancing HIF-1α degradation induced by pVHL.
Kim JA; Choi DK; Min JS; Kang I; Kim JC; Kim S; Ahn JK
FEBS J; 2018 Jan; 285(1):115-126. PubMed ID: 29121446
[TBL] [Abstract][Full Text] [Related]
20. HIF hydroxylation and cellular oxygen sensing.
Metzen E; Ratcliffe PJ
Biol Chem; 2004; 385(3-4):223-30. PubMed ID: 15134335
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]