BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

174 related articles for article (PubMed ID: 21317286)

  • 1. BAD contributes to RAF-mediated proliferation and cooperates with B-RAF-V600E in cancer signaling.
    Polzien L; Baljuls A; Albrecht M; Hekman M; Rapp UR
    J Biol Chem; 2011 May; 286(20):17934-44. PubMed ID: 21317286
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of novel in vivo phosphorylation sites of the human proapoptotic protein BAD: pore-forming activity of BAD is regulated by phosphorylation.
    Polzien L; Baljuls A; Rennefahrt UEE; Fischer A; Schmitz W; Zahedi RP; Sickmann A; Metz R; Albert S; Benz R; Hekman M; Rapp UR
    J Biol Chem; 2009 Oct; 284(41):28004-28020. PubMed ID: 19667065
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Oncogenic B-RafV600E inhibits apoptosis and promotes ERK-dependent inactivation of Bad and Bim.
    Sheridan C; Brumatti G; Martin SJ
    J Biol Chem; 2008 Aug; 283(32):22128-35. PubMed ID: 18508762
    [TBL] [Abstract][Full Text] [Related]  

  • 4. p21-Activated kinase 1 (Pak1) phosphorylates BAD directly at serine 111 in vitro and indirectly through Raf-1 at serine 112.
    Ye DZ; Jin S; Zhuo Y; Field J
    PLoS One; 2011; 6(11):e27637. PubMed ID: 22096607
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mutant B-RAF mediates resistance to anoikis via Bad and Bim.
    Boisvert-Adamo K; Aplin AE
    Oncogene; 2008 May; 27(23):3301-12. PubMed ID: 18246127
    [TBL] [Abstract][Full Text] [Related]  

  • 6. p21-activated Kinase 1 (Pak1)-dependent phosphorylation of Raf-1 regulates its mitochondrial localization, phosphorylation of BAD, and Bcl-2 association.
    Jin S; Zhuo Y; Guo W; Field J
    J Biol Chem; 2005 Jul; 280(26):24698-705. PubMed ID: 15849194
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Raf-1 and B-Raf promote protein kinase C theta interaction with BAD.
    Hindley A; Kolch W
    Cell Signal; 2007 Mar; 19(3):547-55. PubMed ID: 17011751
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Bag-1 stimulates Bad phosphorylation through activation of Akt and Raf kinases to mediate cell survival in breast cancer.
    Kizilboga T; Baskale EA; Yildiz J; Akcay IM; Zemheri E; Can ND; Ozden C; Demir S; Ezberci F; Dinler-Doganay G
    BMC Cancer; 2019 Dec; 19(1):1254. PubMed ID: 31883527
    [TBL] [Abstract][Full Text] [Related]  

  • 9. p21-activated kinase 1 (PAK1) can promote ERK activation in a kinase-independent manner.
    Wang Z; Fu M; Wang L; Liu J; Li Y; Brakebusch C; Mei Q
    J Biol Chem; 2013 Jul; 288(27):20093-9. PubMed ID: 23653349
    [TBL] [Abstract][Full Text] [Related]  

  • 10. RAS signaling promotes resistance to JAK inhibitors by suppressing BAD-mediated apoptosis.
    Winter PS; Sarosiek KA; Lin KH; Meggendorfer M; Schnittger S; Letai A; Wood KC
    Sci Signal; 2014 Dec; 7(357):ra122. PubMed ID: 25538080
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mcl-1 is required for melanoma cell resistance to anoikis.
    Boisvert-Adamo K; Longmate W; Abel EV; Aplin AE
    Mol Cancer Res; 2009 Apr; 7(4):549-56. PubMed ID: 19372583
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of Raf-1 alters multiple downstream pathways to induce pancreatic beta-cell apoptosis.
    Alejandro EU; Johnson JD
    J Biol Chem; 2008 Jan; 283(4):2407-17. PubMed ID: 18006502
    [TBL] [Abstract][Full Text] [Related]  

  • 13. CaMKII-γ mediates phosphorylation of BAD at Ser170 to regulate cytokine-dependent survival and proliferation.
    Hojabrpour P; Waissbluth I; Ghaffari M; Cox ME; Duronio V
    Biochem J; 2012 Feb; 442(1):139-49. PubMed ID: 22103330
    [TBL] [Abstract][Full Text] [Related]  

  • 14. ERK2 phosphorylation of serine 77 regulates Bmf pro-apoptotic activity.
    Shao Y; Aplin AE
    Cell Death Dis; 2012 Jan; 3(1):e253. PubMed ID: 22258404
    [TBL] [Abstract][Full Text] [Related]  

  • 15. ArgBP2gamma interacts with Akt and p21-activated kinase-1 and promotes cell survival.
    Yuan ZQ; Kim D; Kaneko S; Sussman M; Bokoch GM; Kruh GD; Nicosia SV; Testa JR; Cheng JQ
    J Biol Chem; 2005 Jun; 280(22):21483-90. PubMed ID: 15784622
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Functional analysis of the regulatory requirements of B-Raf and the B-Raf(V600E) oncoprotein.
    Brummer T; Martin P; Herzog S; Misawa Y; Daly RJ; Reth M
    Oncogene; 2006 Oct; 25(47):6262-76. PubMed ID: 16702958
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The survival function of the Bcr-Abl oncogene is mediated by Bad-dependent and -independent pathways: roles for phosphatidylinositol 3-kinase and Raf.
    Neshat MS; Raitano AB; Wang HG; Reed JC; Sawyers CL
    Mol Cell Biol; 2000 Feb; 20(4):1179-86. PubMed ID: 10648603
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF-selective manner.
    Joseph EW; Pratilas CA; Poulikakos PI; Tadi M; Wang W; Taylor BS; Halilovic E; Persaud Y; Xing F; Viale A; Tsai J; Chapman PB; Bollag G; Solit DB; Rosen N
    Proc Natl Acad Sci U S A; 2010 Aug; 107(33):14903-8. PubMed ID: 20668238
    [TBL] [Abstract][Full Text] [Related]  

  • 19. p21-activated kinase 1 phosphorylates the death agonist bad and protects cells from apoptosis.
    Schürmann A; Mooney AF; Sanders LC; Sells MA; Wang HG; Reed JC; Bokoch GM
    Mol Cell Biol; 2000 Jan; 20(2):453-61. PubMed ID: 10611223
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Knockdown of PAK4 or PAK1 inhibits the proliferation of mutant KRAS colon cancer cells independently of RAF/MEK/ERK and PI3K/AKT signaling.
    Tabusa H; Brooks T; Massey AJ
    Mol Cancer Res; 2013 Feb; 11(2):109-21. PubMed ID: 23233484
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.