462 related articles for article (PubMed ID: 21317875)
1. Structure of the Ire1 autophosphorylation complex and implications for the unfolded protein response.
Ali MM; Bagratuni T; Davenport EL; Nowak PR; Silva-Santisteban MC; Hardcastle A; McAndrews C; Rowlands MG; Morgan GJ; Aherne W; Collins I; Davies FE; Pearl LH
EMBO J; 2011 Mar; 30(5):894-905. PubMed ID: 21317875
[TBL] [Abstract][Full Text] [Related]
2. Cytoplasmic IRE1alpha-mediated XBP1 mRNA splicing in the absence of nuclear processing and endoplasmic reticulum stress.
Back SH; Lee K; Vink E; Kaufman RJ
J Biol Chem; 2006 Jul; 281(27):18691-706. PubMed ID: 16644724
[TBL] [Abstract][Full Text] [Related]
3. IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response.
Lee K; Tirasophon W; Shen X; Michalak M; Prywes R; Okada T; Yoshida H; Mori K; Kaufman RJ
Genes Dev; 2002 Feb; 16(4):452-66. PubMed ID: 11850408
[TBL] [Abstract][Full Text] [Related]
4. Potent and selective inhibitors of the inositol-requiring enzyme 1 endoribonuclease.
Volkmann K; Lucas JL; Vuga D; Wang X; Brumm D; Stiles C; Kriebel D; Der-Sarkissian A; Krishnan K; Schweitzer C; Liu Z; Malyankar UM; Chiovitti D; Canny M; Durocher D; Sicheri F; Patterson JB
J Biol Chem; 2011 Apr; 286(14):12743-55. PubMed ID: 21303903
[TBL] [Abstract][Full Text] [Related]
5. Phosphoregulation of Ire1 RNase splicing activity.
Prischi F; Nowak PR; Carrara M; Ali MM
Nat Commun; 2014 Apr; 5():3554. PubMed ID: 24704861
[TBL] [Abstract][Full Text] [Related]
6. Principles of IRE1 modulation using chemical tools.
Lee KP; Sicheri F
Methods Enzymol; 2011; 490():271-94. PubMed ID: 21266256
[TBL] [Abstract][Full Text] [Related]
7. Acute Endoplasmic Reticulum Stress-Independent Unconventional Splicing of XBP1 mRNA in the Nucleus of Mammalian Cells.
Wang Y; Xing P; Cui W; Wang W; Cui Y; Ying G; Wang X; Li B
Int J Mol Sci; 2015 Jun; 16(6):13302-21. PubMed ID: 26068456
[TBL] [Abstract][Full Text] [Related]
8. Ire1-mediated decay in mammalian cells relies on mRNA sequence, structure, and translational status.
Moore K; Hollien J
Mol Biol Cell; 2015 Aug; 26(16):2873-84. PubMed ID: 26108623
[TBL] [Abstract][Full Text] [Related]
9. Transcriptional induction of the human asparagine synthetase gene during the unfolded protein response does not require the ATF6 and IRE1/XBP1 arms of the pathway.
Gjymishka A; Su N; Kilberg MS
Biochem J; 2009 Feb; 417(3):695-703. PubMed ID: 18840095
[TBL] [Abstract][Full Text] [Related]
10. Mechanistic rationale for targeting the unfolded protein response in pre-B acute lymphoblastic leukemia.
Kharabi Masouleh B; Geng H; Hurtz C; Chan LN; Logan AC; Chang MS; Huang C; Swaminathan S; Sun H; Paietta E; Melnick AM; Koeffler P; Müschen M
Proc Natl Acad Sci U S A; 2014 May; 111(21):E2219-28. PubMed ID: 24821775
[TBL] [Abstract][Full Text] [Related]
11. A conformational RNA zipper promotes intron ejection during non-conventional XBP1 mRNA splicing.
Peschek J; Acosta-Alvear D; Mendez AS; Walter P
EMBO Rep; 2015 Dec; 16(12):1688-98. PubMed ID: 26483401
[TBL] [Abstract][Full Text] [Related]
12. Resveratrol triggers the pro-apoptotic endoplasmic reticulum stress response and represses pro-survival XBP1 signaling in human multiple myeloma cells.
Wang FM; Galson DL; Roodman GD; Ouyang H
Exp Hematol; 2011 Oct; 39(10):999-1006. PubMed ID: 21723843
[TBL] [Abstract][Full Text] [Related]
13. HSP72 protects cells from ER stress-induced apoptosis via enhancement of IRE1alpha-XBP1 signaling through a physical interaction.
Gupta S; Deepti A; Deegan S; Lisbona F; Hetz C; Samali A
PLoS Biol; 2010 Jul; 8(7):e1000410. PubMed ID: 20625543
[TBL] [Abstract][Full Text] [Related]
14. Hepatitis C virus suppresses the IRE1-XBP1 pathway of the unfolded protein response.
Tardif KD; Mori K; Kaufman RJ; Siddiqui A
J Biol Chem; 2004 Apr; 279(17):17158-64. PubMed ID: 14960590
[TBL] [Abstract][Full Text] [Related]
15. Peptides derived from the bifunctional kinase/RNase enzyme IRE1α modulate IRE1α activity and protect cells from endoplasmic reticulum stress.
Bouchecareilh M; Higa A; Fribourg S; Moenner M; Chevet E
FASEB J; 2011 Sep; 25(9):3115-29. PubMed ID: 21680894
[TBL] [Abstract][Full Text] [Related]
16. Identification of autophosphorylation inhibitors of the inositol-requiring enzyme 1 alpha (IRE1α) by high-throughput screening using a DELFIA assay.
Newbatt Y; Hardcastle A; McAndrew PC; Strover JA; Mirza A; Morgan GJ; Burke R; Davies FE; Collins I; van Montfort RL
J Biomol Screen; 2013 Mar; 18(3):298-308. PubMed ID: 23139381
[TBL] [Abstract][Full Text] [Related]
17. A novel chemical, STF-083010, reverses tamoxifen-related drug resistance in breast cancer by inhibiting IRE1/XBP1.
Ming J; Ruan S; Wang M; Ye D; Fan N; Meng Q; Tian B; Huang T
Oncotarget; 2015 Dec; 6(38):40692-703. PubMed ID: 26517687
[TBL] [Abstract][Full Text] [Related]
18. The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis.
Zhang K; Wong HN; Song B; Miller CN; Scheuner D; Kaufman RJ
J Clin Invest; 2005 Feb; 115(2):268-81. PubMed ID: 15690081
[TBL] [Abstract][Full Text] [Related]
19. Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligands.
Ferri E; Le Thomas A; Wallweber HA; Day ES; Walters BT; Kaufman SE; Braun MG; Clark KR; Beresini MH; Mortara K; Chen YA; Canter B; Phung W; Liu PS; Lammens A; Ashkenazi A; Rudolph J; Wang W
Nat Commun; 2020 Dec; 11(1):6387. PubMed ID: 33318494
[TBL] [Abstract][Full Text] [Related]
20. A Molecular Mechanism for Turning Off IRE1α Signaling during Endoplasmic Reticulum Stress.
Li X; Sun S; Appathurai S; Sundaram A; Plumb R; Mariappan M
Cell Rep; 2020 Dec; 33(13):108563. PubMed ID: 33378667
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]