325 related articles for article (PubMed ID: 21321328)
1. Regulation of the NKCC2 ion cotransporter by SPAK-OSR1-dependent and -independent pathways.
Richardson C; Sakamoto K; de los Heros P; Deak M; Campbell DG; Prescott AR; Alessi DR
J Cell Sci; 2011 Mar; 124(Pt 5):789-800. PubMed ID: 21321328
[TBL] [Abstract][Full Text] [Related]
2. SPAK/OSR1 regulate NKCC1 and WNK activity: analysis of WNK isoform interactions and activation by T-loop trans-autophosphorylation.
Thastrup JO; Rafiqi FH; Vitari AC; Pozo-Guisado E; Deak M; Mehellou Y; Alessi DR
Biochem J; 2012 Jan; 441(1):325-37. PubMed ID: 22032326
[TBL] [Abstract][Full Text] [Related]
3. SPAK and OSR1 play essential roles in potassium homeostasis through actions on the distal convoluted tubule.
Ferdaus MZ; Barber KW; López-Cayuqueo KI; Terker AS; Argaiz ER; Gassaway BM; Chambrey R; Gamba G; Rinehart J; McCormick JA
J Physiol; 2016 Sep; 594(17):4945-66. PubMed ID: 27068441
[TBL] [Abstract][Full Text] [Related]
4. Novel mechanisms of Na+ retention in obesity: phosphorylation of NKCC2 and regulation of SPAK/OSR1 by AMPK.
Davies M; Fraser SA; Galic S; Choy SW; Katerelos M; Gleich K; Kemp BE; Mount PF; Power DA
Am J Physiol Renal Physiol; 2014 Jul; 307(1):F96-F106. PubMed ID: 24808538
[TBL] [Abstract][Full Text] [Related]
5. SPAK isoforms and OSR1 regulate sodium-chloride co-transporters in a nephron-specific manner.
Grimm PR; Taneja TK; Liu J; Coleman R; Chen YY; Delpire E; Wade JB; Welling PA
J Biol Chem; 2012 Nov; 287(45):37673-90. PubMed ID: 22977235
[TBL] [Abstract][Full Text] [Related]
6. Dysregulation of the WNK4-SPAK/OSR1 pathway has a minor effect on baseline NKCC2 phosphorylation.
Maeoka Y; Nguyen LT; Sharma A; Cornelius RJ; Su XT; Gutierrez MR; Carbajal-Contreras H; Castañeda-Bueno M; Gamba G; McCormick JA
Am J Physiol Renal Physiol; 2024 Jan; 326(1):F39-F56. PubMed ID: 37881876
[TBL] [Abstract][Full Text] [Related]
7. Activation of the thiazide-sensitive Na+-Cl- cotransporter by the WNK-regulated kinases SPAK and OSR1.
Richardson C; Rafiqi FH; Karlsson HK; Moleleki N; Vandewalle A; Campbell DG; Morrice NA; Alessi DR
J Cell Sci; 2008 Mar; 121(Pt 5):675-84. PubMed ID: 18270262
[TBL] [Abstract][Full Text] [Related]
8. WNK1 regulates phosphorylation of cation-chloride-coupled cotransporters via the STE20-related kinases, SPAK and OSR1.
Moriguchi T; Urushiyama S; Hisamoto N; Iemura S; Uchida S; Natsume T; Matsumoto K; Shibuya H
J Biol Chem; 2005 Dec; 280(52):42685-93. PubMed ID: 16263722
[TBL] [Abstract][Full Text] [Related]
9. Impaired phosphorylation of Na(+)-K(+)-2Cl(-) cotransporter by oxidative stress-responsive kinase-1 deficiency manifests hypotension and Bartter-like syndrome.
Lin SH; Yu IS; Jiang ST; Lin SW; Chu P; Chen A; Sytwu HK; Sohara E; Uchida S; Sasaki S; Yang SS
Proc Natl Acad Sci U S A; 2011 Oct; 108(42):17538-43. PubMed ID: 21972418
[TBL] [Abstract][Full Text] [Related]
10. Cotransporters, WNKs and hypertension: an update.
Flatman PW
Curr Opin Nephrol Hypertens; 2008 Mar; 17(2):186-92. PubMed ID: 18277153
[TBL] [Abstract][Full Text] [Related]
11. Role of the WNK-activated SPAK kinase in regulating blood pressure.
Rafiqi FH; Zuber AM; Glover M; Richardson C; Fleming S; Jovanović S; Jovanović A; O'Shaughnessy KM; Alessi DR
EMBO Mol Med; 2010 Feb; 2(2):63-75. PubMed ID: 20091762
[TBL] [Abstract][Full Text] [Related]
12. The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+-Cl- co-transporters.
de Los Heros P; Alessi DR; Gourlay R; Campbell DG; Deak M; Macartney TJ; Kahle KT; Zhang J
Biochem J; 2014 Mar; 458(3):559-73. PubMed ID: 24393035
[TBL] [Abstract][Full Text] [Related]
13. The CUL3-KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt interaction.
Ohta A; Schumacher FR; Mehellou Y; Johnson C; Knebel A; Macartney TJ; Wood NT; Alessi DR; Kurz T
Biochem J; 2013 Apr; 451(1):111-22. PubMed ID: 23387299
[TBL] [Abstract][Full Text] [Related]
14. Effect of heterozygous deletion of WNK1 on the WNK-OSR1/ SPAK-NCC/NKCC1/NKCC2 signal cascade in the kidney and blood vessels.
Susa K; Kita S; Iwamoto T; Yang SS; Lin SH; Ohta A; Sohara E; Rai T; Sasaki S; Alessi DR; Uchida S
Clin Exp Nephrol; 2012 Aug; 16(4):530-8. PubMed ID: 22294159
[TBL] [Abstract][Full Text] [Related]
15. Arginine vasopressin regulates the renal Na
Carbajal-Contreras H; Murillo-de-Ozores AR; Magaña-Avila G; Marquez-Salinas A; Bourqui L; Tellez-Sutterlin M; Bahena-Lopez JP; Cortes-Arroyo E; Behn-Eschenburg SG; Lopez-Saavedra A; Vazquez N; Ellison DH; Loffing J; Gamba G; Castañeda-Bueno M
Am J Physiol Renal Physiol; 2024 Feb; 326(2):F285-F299. PubMed ID: 38096266
[TBL] [Abstract][Full Text] [Related]
16. A novel Ste20-related proline/alanine-rich kinase (SPAK)-independent pathway involving calcium-binding protein 39 (Cab39) and serine threonine kinase with no lysine member 4 (WNK4) in the activation of Na-K-Cl cotransporters.
Ponce-Coria J; Markadieu N; Austin TM; Flammang L; Rios K; Welling PA; Delpire E
J Biol Chem; 2014 Jun; 289(25):17680-8. PubMed ID: 24811174
[TBL] [Abstract][Full Text] [Related]
17. Role of SPAK and OSR1 signalling in the regulation of NaCl cotransporters.
Mercier-Zuber A; O'Shaughnessy KM
Curr Opin Nephrol Hypertens; 2011 Sep; 20(5):534-40. PubMed ID: 21610494
[TBL] [Abstract][Full Text] [Related]
18. Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1.
Vitari AC; Thastrup J; Rafiqi FH; Deak M; Morrice NA; Karlsson HK; Alessi DR
Biochem J; 2006 Jul; 397(1):223-31. PubMed ID: 16669787
[TBL] [Abstract][Full Text] [Related]
19. Regulation of NKCC2 by a chloride-sensing mechanism involving the WNK3 and SPAK kinases.
Ponce-Coria J; San-Cristobal P; Kahle KT; Vazquez N; Pacheco-Alvarez D; de Los Heros P; Juárez P; Muñoz E; Michel G; Bobadilla NA; Gimenez I; Lifton RP; Hebert SC; Gamba G
Proc Natl Acad Sci U S A; 2008 Jun; 105(24):8458-63. PubMed ID: 18550832
[TBL] [Abstract][Full Text] [Related]
20. The regulation of salt transport and blood pressure by the WNK-SPAK/OSR1 signalling pathway.
Richardson C; Alessi DR
J Cell Sci; 2008 Oct; 121(Pt 20):3293-304. PubMed ID: 18843116
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
