BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

234 related articles for article (PubMed ID: 21325207)

  • 1. MUC1-C oncoprotein promotes STAT3 activation in an autoinductive regulatory loop.
    Ahmad R; Rajabi H; Kosugi M; Joshi MD; Alam M; Vasir B; Kawano T; Kharbanda S; Kufe D
    Sci Signal; 2011 Feb; 4(160):ra9. PubMed ID: 21325207
    [TBL] [Abstract][Full Text] [Related]  

  • 2. HOTAIR modulates hepatocellular carcinoma progression by activating FUT8/core-fucosylated Hsp90/MUC1/STAT3 feedback loop via JAK1/STAT3 cascade.
    Guo Y; Liu B; Huang T; Qi X; Li S
    Dig Liver Dis; 2023 Jan; 55(1):113-122. PubMed ID: 35504805
    [TBL] [Abstract][Full Text] [Related]  

  • 3. MUC1-C oncoprotein functions as a direct activator of the nuclear factor-kappaB p65 transcription factor.
    Ahmad R; Raina D; Joshi MD; Kawano T; Ren J; Kharbanda S; Kufe D
    Cancer Res; 2009 Sep; 69(17):7013-21. PubMed ID: 19706766
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MUC1 protein induces urokinase-type plasminogen activator (uPA) by forming a complex with NF-κB p65 transcription factor and binding to the uPA promoter, leading to enhanced invasiveness of cancer cells.
    Mori Y; Akita K; Tanida S; Ishida A; Toda M; Inoue M; Yashiro M; Sawada T; Hirakawa K; Nakada H
    J Biol Chem; 2014 Dec; 289(51):35193-204. PubMed ID: 25371209
    [TBL] [Abstract][Full Text] [Related]  

  • 5. JAK1 activates STAT3 activity in non-small-cell lung cancer cells and IL-6 neutralizing antibodies can suppress JAK1-STAT3 signaling.
    Song L; Rawal B; Nemeth JA; Haura EB
    Mol Cancer Ther; 2011 Mar; 10(3):481-94. PubMed ID: 21216930
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MUC1-C oncoprotein induces TCF7L2 transcription factor activation and promotes cyclin D1 expression in human breast cancer cells.
    Rajabi H; Ahmad R; Jin C; Kosugi M; Alam M; Joshi MD; Kufe D
    J Biol Chem; 2012 Mar; 287(13):10703-10713. PubMed ID: 22318732
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Genetic regulation of MUC1 expression by Helicobacter pylori in gastric cancer cells.
    Guang W; Czinn SJ; Blanchard TG; Kim KC; Lillehoj EP
    Biochem Biophys Res Commun; 2014 Feb; 445(1):145-50. PubMed ID: 24491543
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cyclophilins contribute to Stat3 signaling and survival of multiple myeloma cells.
    Bauer K; Kretzschmar AK; Cvijic H; Blumert C; Löffler D; Brocke-Heidrich K; Schiene-Fischer C; Fischer G; Sinz A; Clevenger CV; Horn F
    Oncogene; 2009 Aug; 28(31):2784-95. PubMed ID: 19503092
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular crosstalk between MUC1 and STAT3 influences the anti-proliferative effect of Napabucasin in epithelial cancers.
    Bose M; Sanders A; Handa A; Vora A; Cardona MR; Brouwer C; Mukherjee P
    Sci Rep; 2024 Feb; 14(1):3178. PubMed ID: 38326371
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeting the eIF4A RNA helicase blocks translation of the MUC1-C oncoprotein.
    Jin C; Rajabi H; Rodrigo CM; Porco JA; Kufe D
    Oncogene; 2013 Apr; 32(17):2179-88. PubMed ID: 22689062
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cooperativity of the MUC1 oncoprotein and STAT1 pathway in poor prognosis human breast cancer.
    Khodarev N; Ahmad R; Rajabi H; Pitroda S; Kufe T; McClary C; Joshi MD; MacDermed D; Weichselbaum R; Kufe D
    Oncogene; 2010 Feb; 29(6):920-9. PubMed ID: 19915608
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The MUC1-C oncoprotein binds to the BH3 domain of the pro-apoptotic BAX protein and blocks BAX function.
    Ahmad R; Alam M; Rajabi H; Kufe D
    J Biol Chem; 2012 Jun; 287(25):20866-75. PubMed ID: 22544745
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Activation of the protein tyrosine phosphatase SHP2 via the interleukin-6 signal transducing receptor protein gp130 requires tyrosine kinase Jak1 and limits acute-phase protein expression.
    Schaper F; Gendo C; Eck M; Schmitz J; Grimm C; Anhuf D; Kerr IM; Heinrich PC
    Biochem J; 1998 Nov; 335 ( Pt 3)(Pt 3):557-65. PubMed ID: 9794795
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Herbal remedy magnolol suppresses IL-6-induced STAT3 activation and gene expression in endothelial cells.
    Chen SC; Chang YL; Wang DL; Cheng JJ
    Br J Pharmacol; 2006 May; 148(2):226-32. PubMed ID: 16520748
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MUC1-C oncoprotein regulates glycolysis and pyruvate kinase M2 activity in cancer cells.
    Kosugi M; Ahmad R; Alam M; Uchida Y; Kufe D
    PLoS One; 2011; 6(11):e28234. PubMed ID: 22140559
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interleukin-6 promotes proliferative vitreoretinopathy by inducing epithelial-mesenchymal transition via the JAK1/STAT3 signaling pathway.
    Chen X; Yang W; Deng X; Ye S; Xiao W
    Mol Vis; 2020; 26():517-529. PubMed ID: 32818015
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cooperative interaction between the MUC1-C oncoprotein and the Rab31 GTPase in estrogen receptor-positive breast cancer cells.
    Jin C; Rajabi H; Pitroda S; Li A; Kharbanda A; Weichselbaum R; Kufe D
    PLoS One; 2012; 7(7):e39432. PubMed ID: 22792175
    [TBL] [Abstract][Full Text] [Related]  

  • 18. MUC1-C oncoprotein as a target in breast cancer: activation of signaling pathways and therapeutic approaches.
    Kufe DW
    Oncogene; 2013 Feb; 32(9):1073-81. PubMed ID: 22580612
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The functional role of an interleukin 6-inducible CDK9.STAT3 complex in human gamma-fibrinogen gene expression.
    Hou T; Ray S; Brasier AR
    J Biol Chem; 2007 Dec; 282(51):37091-102. PubMed ID: 17956865
    [TBL] [Abstract][Full Text] [Related]  

  • 20. MUC1-C oncoprotein activates ERK→C/EBPβ signaling and induction of aldehyde dehydrogenase 1A1 in breast cancer cells.
    Alam M; Ahmad R; Rajabi H; Kharbanda A; Kufe D
    J Biol Chem; 2013 Oct; 288(43):30892-903. PubMed ID: 24043631
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.