1213 related articles for article (PubMed ID: 21325420)
1. Evidence that TMPRSS2 activates the severe acute respiratory syndrome coronavirus spike protein for membrane fusion and reduces viral control by the humoral immune response.
Glowacka I; Bertram S; Müller MA; Allen P; Soilleux E; Pfefferle S; Steffen I; Tsegaye TS; He Y; Gnirss K; Niemeyer D; Schneider H; Drosten C; Pöhlmann S
J Virol; 2011 May; 85(9):4122-34. PubMed ID: 21325420
[TBL] [Abstract][Full Text] [Related]
2. Cleavage and activation of the severe acute respiratory syndrome coronavirus spike protein by human airway trypsin-like protease.
Bertram S; Glowacka I; Müller MA; Lavender H; Gnirss K; Nehlmeier I; Niemeyer D; He Y; Simmons G; Drosten C; Soilleux EJ; Jahn O; Steffen I; Pöhlmann S
J Virol; 2011 Dec; 85(24):13363-72. PubMed ID: 21994442
[TBL] [Abstract][Full Text] [Related]
3. Efficient activation of the severe acute respiratory syndrome coronavirus spike protein by the transmembrane protease TMPRSS2.
Matsuyama S; Nagata N; Shirato K; Kawase M; Takeda M; Taguchi F
J Virol; 2010 Dec; 84(24):12658-64. PubMed ID: 20926566
[TBL] [Abstract][Full Text] [Related]
4. TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein.
Heurich A; Hofmann-Winkler H; Gierer S; Liepold T; Jahn O; Pöhlmann S
J Virol; 2014 Jan; 88(2):1293-307. PubMed ID: 24227843
[TBL] [Abstract][Full Text] [Related]
5. SARS-CoV-2 and SARS-CoV Spike-Mediated Cell-Cell Fusion Differ in Their Requirements for Receptor Expression and Proteolytic Activation.
Hörnich BF; Großkopf AK; Schlagowski S; Tenbusch M; Kleine-Weber H; Neipel F; Stahl-Hennig C; Hahn AS
J Virol; 2021 Apr; 95(9):. PubMed ID: 33608407
[TBL] [Abstract][Full Text] [Related]
6. Distinctive Roles of Furin and TMPRSS2 in SARS-CoV-2 Infectivity.
Essalmani R; Jain J; Susan-Resiga D; Andréo U; Evagelidis A; Derbali RM; Huynh DN; Dallaire F; Laporte M; Delpal A; Sutto-Ortiz P; Coutard B; Mapa C; Wilcoxen K; Decroly E; Nq Pham T; Cohen ÉA; Seidah NG
J Virol; 2022 Apr; 96(8):e0012822. PubMed ID: 35343766
[TBL] [Abstract][Full Text] [Related]
7. The spike protein of the emerging betacoronavirus EMC uses a novel coronavirus receptor for entry, can be activated by TMPRSS2, and is targeted by neutralizing antibodies.
Gierer S; Bertram S; Kaup F; Wrensch F; Heurich A; Krämer-Kühl A; Welsch K; Winkler M; Meyer B; Drosten C; Dittmer U; von Hahn T; Simmons G; Hofmann H; Pöhlmann S
J Virol; 2013 May; 87(10):5502-11. PubMed ID: 23468491
[TBL] [Abstract][Full Text] [Related]
8. Different residues in the SARS-CoV spike protein determine cleavage and activation by the host cell protease TMPRSS2.
Reinke LM; Spiegel M; Plegge T; Hartleib A; Nehlmeier I; Gierer S; Hoffmann M; Hofmann-Winkler H; Winkler M; Pöhlmann S
PLoS One; 2017; 12(6):e0179177. PubMed ID: 28636671
[TBL] [Abstract][Full Text] [Related]
9. ACE2 acts as a novel regulator of TMPRSS2-catalyzed proteolytic activation of influenza A virus in airway cells.
Heindl MR; Rupp A-L; Schwerdtner M; Bestle D; Harbig A; De Rocher A; Schmacke LC; Staker B; Steinmetzer T; Stein DA; Moulton HM; Böttcher-Friebertshäuser E
J Virol; 2024 Apr; 98(4):e0010224. PubMed ID: 38470058
[TBL] [Abstract][Full Text] [Related]
10. S protein of severe acute respiratory syndrome-associated coronavirus mediates entry into hepatoma cell lines and is targeted by neutralizing antibodies in infected patients.
Hofmann H; Hattermann K; Marzi A; Gramberg T; Geier M; Krumbiegel M; Kuate S; Uberla K; Niedrig M; Pöhlmann S
J Virol; 2004 Jun; 78(12):6134-42. PubMed ID: 15163706
[TBL] [Abstract][Full Text] [Related]
11. Anti-severe acute respiratory syndrome coronavirus spike antibodies trigger infection of human immune cells via a pH- and cysteine protease-independent FcγR pathway.
Jaume M; Yip MS; Cheung CY; Leung HL; Li PH; Kien F; Dutry I; Callendret B; Escriou N; Altmeyer R; Nal B; Daëron M; Bruzzone R; Peiris JS
J Virol; 2011 Oct; 85(20):10582-97. PubMed ID: 21775467
[TBL] [Abstract][Full Text] [Related]
12. The TMPRSS2 Inhibitor Nafamostat Reduces SARS-CoV-2 Pulmonary Infection in Mouse Models of COVID-19.
Li K; Meyerholz DK; Bartlett JA; McCray PB
mBio; 2021 Aug; 12(4):e0097021. PubMed ID: 34340553
[TBL] [Abstract][Full Text] [Related]
13. TMPRSS2 Isoform 1 Activates Respiratory Viruses and Is Expressed in Viral Target Cells.
Zmora P; Moldenhauer AS; Hofmann-Winkler H; Pöhlmann S
PLoS One; 2015; 10(9):e0138380. PubMed ID: 26379044
[TBL] [Abstract][Full Text] [Related]
14. SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor.
Hoffmann M; Kleine-Weber H; Schroeder S; Krüger N; Herrler T; Erichsen S; Schiergens TS; Herrler G; Wu NH; Nitsche A; Müller MA; Drosten C; Pöhlmann S
Cell; 2020 Apr; 181(2):271-280.e8. PubMed ID: 32142651
[TBL] [Abstract][Full Text] [Related]
15. TMPRSS2 Contributes to Virus Spread and Immunopathology in the Airways of Murine Models after Coronavirus Infection.
Iwata-Yoshikawa N; Okamura T; Shimizu Y; Hasegawa H; Takeda M; Nagata N
J Virol; 2019 Mar; 93(6):. PubMed ID: 30626688
[TBL] [Abstract][Full Text] [Related]
16. [Protease-dependent cell entry mechanism of coronaviruses].
Matsuyama S
Uirusu; 2011 Jun; 61(1):109-16. PubMed ID: 21972562
[TBL] [Abstract][Full Text] [Related]
17. Dual Inhibition of Vacuolar-ATPase and TMPRSS2 Is Required for Complete Blockade of SARS-CoV-2 Entry into Cells.
Icho S; Rujas E; Muthuraman K; Tam J; Liang H; Landreth S; Liao M; Falzarano D; Julien JP; Melnyk RA
Antimicrob Agents Chemother; 2022 Jul; 66(7):e0043922. PubMed ID: 35703551
[TBL] [Abstract][Full Text] [Related]
18. TMPRSS2 activates the human coronavirus 229E for cathepsin-independent host cell entry and is expressed in viral target cells in the respiratory epithelium.
Bertram S; Dijkman R; Habjan M; Heurich A; Gierer S; Glowacka I; Welsch K; Winkler M; Schneider H; Hofmann-Winkler H; Thiel V; Pöhlmann S
J Virol; 2013 Jun; 87(11):6150-60. PubMed ID: 23536651
[TBL] [Abstract][Full Text] [Related]
19. Activation of the SARS coronavirus spike protein via sequential proteolytic cleavage at two distinct sites.
Belouzard S; Chu VC; Whittaker GR
Proc Natl Acad Sci U S A; 2009 Apr; 106(14):5871-6. PubMed ID: 19321428
[TBL] [Abstract][Full Text] [Related]
20. Highly Efficient SARS-CoV-2 Infection of Human Cardiomyocytes: Spike Protein-Mediated Cell Fusion and Its Inhibition.
Navaratnarajah CK; Pease DR; Halfmann PJ; Taye B; Barkhymer A; Howell KG; Charlesworth JE; Christensen TA; Kawaoka Y; Cattaneo R; Schneider JW;
J Virol; 2021 Nov; 95(24):e0136821. PubMed ID: 34613786
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]