BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

141 related articles for article (PubMed ID: 21329651)

  • 1. 4-O-methylascochlorin, methylated derivative of ascochlorin, stabilizes HIF-1α via AMPK activation.
    Jeong JH; Kang JH; Hwang SL; Cho HJ; Park KK; Park YY; Chung IK; Chang HW; Kim CH; Min KS; Kim HD; Magae J; Kang SS; Chang YC
    Biochem Biophys Res Commun; 2011 Mar; 406(3):353-8. PubMed ID: 21329651
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ascochlorin inhibits growth factor-induced HIF-1α activation and tumor-angiogenesis through the suppression of EGFR/ERK/p70S6K signaling pathway in human cervical carcinoma cells.
    Jeong JH; Jeong YJ; Cho HJ; Shin JM; Kang JH; Park KK; Park YY; Chung IK; Chang HW; Magae J
    J Cell Biochem; 2012 Apr; 113(4):1302-13. PubMed ID: 22109717
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Reactive oxygen species stabilize hypoxia-inducible factor-1 alpha protein and stimulate transcriptional activity via AMP-activated protein kinase in DU145 human prostate cancer cells.
    Jung SN; Yang WK; Kim J; Kim HS; Kim EJ; Yun H; Park H; Kim SS; Choe W; Kang I; Ha J
    Carcinogenesis; 2008 Apr; 29(4):713-21. PubMed ID: 18258605
    [TBL] [Abstract][Full Text] [Related]  

  • 4. AMP-activated protein kinase activity is required for vanadate-induced hypoxia-inducible factor 1alpha expression in DU145 cells.
    Hwang JT; Lee M; Jung SN; Lee HJ; Kang I; Kim SS; Ha J
    Carcinogenesis; 2004 Dec; 25(12):2497-507. PubMed ID: 15297373
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Upregulation of AMPK by 4-O-methylascochlorin promotes autophagy via the HIF-1α expression.
    Seok JY; Jeong YJ; Hwang SK; Kim CH; Magae J; Chang YC
    J Cell Mol Med; 2018 Dec; 22(12):6345-6356. PubMed ID: 30338933
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Silibinin inhibits hypoxia-inducible factor-1alpha and mTOR/p70S6K/4E-BP1 signalling pathway in human cervical and hepatoma cancer cells: implications for anticancer therapy.
    García-Maceira P; Mateo J
    Oncogene; 2009 Jan; 28(3):313-24. PubMed ID: 18978810
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mammalian target of rapamycin mediates the angiogenic effects of leptin in human hepatic stellate cells.
    Aleffi S; Navari N; Delogu W; Galastri S; Novo E; Rombouts K; Pinzani M; Parola M; Marra F
    Am J Physiol Gastrointest Liver Physiol; 2011 Aug; 301(2):G210-9. PubMed ID: 21252047
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Reactive oxygen species regulate epidermal growth factor-induced vascular endothelial growth factor and hypoxia-inducible factor-1alpha expression through activation of AKT and P70S6K1 in human ovarian cancer cells.
    Liu LZ; Hu XW; Xia C; He J; Zhou Q; Shi X; Fang J; Jiang BH
    Free Radic Biol Med; 2006 Nov; 41(10):1521-33. PubMed ID: 17045920
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Reactive oxygen species regulate insulin-induced VEGF and HIF-1alpha expression through the activation of p70S6K1 in human prostate cancer cells.
    Zhou Q; Liu LZ; Fu B; Hu X; Shi X; Fang J; Jiang BH
    Carcinogenesis; 2007 Jan; 28(1):28-37. PubMed ID: 16774940
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Suppression of c-Myc induces apoptosis via an AMPK/mTOR-dependent pathway by 4-O-methyl-ascochlorin in leukemia cells.
    Shin JM; Jeong YJ; Cho HJ; Magae J; Bae YS; Chang YC
    Apoptosis; 2016 May; 21(5):657-68. PubMed ID: 26922069
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activation of hypoxia-inducible factor 1 in human T-cell leukaemia virus type 1-infected cell lines and primary adult T-cell leukaemia cells.
    Tomita M; Semenza GL; Michiels C; Matsuda T; Uchihara JN; Okudaira T; Tanaka Y; Taira N; Ohshiro K; Mori N
    Biochem J; 2007 Sep; 406(2):317-23. PubMed ID: 17576198
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Caffeine inhibits adenosine-induced accumulation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and interleukin-8 expression in hypoxic human colon cancer cells.
    Merighi S; Benini A; Mirandola P; Gessi S; Varani K; Simioni C; Leung E; Maclennan S; Baraldi PG; Borea PA
    Mol Pharmacol; 2007 Aug; 72(2):395-406. PubMed ID: 17488804
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 4-
    Magae J; Furukawa C; Kuwahara S; Jeong YJ; Nakajima H; Chang YC
    Biosci Biotechnol Biochem; 2019 Dec; 83(12):2244-2248. PubMed ID: 31392931
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Critical roles of AMP-activated protein kinase in the carcinogenic metal-induced expression of VEGF and HIF-1 proteins in DU145 prostate carcinoma.
    Lee M; Hwang JT; Yun H; Kim EJ; Kim MJ; Kim SS; Ha J
    Biochem Pharmacol; 2006 Jun; 72(1):91-103. PubMed ID: 16678800
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Adenosine modulates vascular endothelial growth factor expression via hypoxia-inducible factor-1 in human glioblastoma cells.
    Merighi S; Benini A; Mirandola P; Gessi S; Varani K; Leung E; Maclennan S; Borea PA
    Biochem Pharmacol; 2006 Jun; 72(1):19-31. PubMed ID: 16682012
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A quassinoid 6alpha-tigloyloxychaparrinone inhibits hypoxia-inducible factor-1 pathway by inhibition of eukaryotic translation initiation factor 4E phosphorylation.
    Jin X; Jin HR; Lee D; Lee JH; Kim SK; Lee JJ
    Eur J Pharmacol; 2008 Sep; 592(1-3):41-7. PubMed ID: 18639543
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Does endogenous fatty acid metabolism allow cancer cells to sense hypoxia and mediate hypoxic vasodilatation? Characterization of a novel molecular connection between fatty acid synthase (FAS) and hypoxia-inducible factor-1alpha (HIF-1alpha)-related expression of vascular endothelial growth factor (VEGF) in cancer cells overexpressing her-2/neu oncogene.
    Menendez JA; Vellon L; Oza BP; Lupu R
    J Cell Biochem; 2005 Apr; 94(5):857-63. PubMed ID: 15669079
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Imperatorin suppresses proliferation and angiogenesis of human colon cancer cell by targeting HIF-1α via the mTOR/p70S6K/4E-BP1 and MAPK pathways.
    Mi C; Ma J; Wang KS; Zuo HX; Wang Z; Li MY; Piao LX; Xu GH; Li X; Quan ZS; Jin X
    J Ethnopharmacol; 2017 May; 203():27-38. PubMed ID: 28341244
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Interactions between HIF-1α and AMPK in the regulation of cellular hypoxia adaptation in chronic kidney disease.
    Li H; Satriano J; Thomas JL; Miyamoto S; Sharma K; Pastor-Soler NM; Hallows KR; Singh P
    Am J Physiol Renal Physiol; 2015 Sep; 309(5):F414-28. PubMed ID: 26136559
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 4-O-methylascochlorin activates autophagy by activating AMPK and suppressing c-Myc in glioblastoma.
    Hwang SK; Han SY; Jeong YJ; Magae J; Bae YS; Chang YC
    J Biochem Mol Toxicol; 2020 Oct; 34(10):e22552. PubMed ID: 32562591
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.