188 related articles for article (PubMed ID: 21329884)
1. Clk2 and B56β mediate insulin-regulated assembly of the PP2A phosphatase holoenzyme complex on Akt.
Rodgers JT; Vogel RO; Puigserver P
Mol Cell; 2011 Feb; 41(4):471-9. PubMed ID: 21329884
[TBL] [Abstract][Full Text] [Related]
2. Molecular determinants for PP2A substrate specificity: charged residues mediate dephosphorylation of tyrosine hydroxylase by the PP2A/B' regulatory subunit.
Saraf A; Oberg EA; Strack S
Biochemistry; 2010 Feb; 49(5):986-95. PubMed ID: 20017541
[TBL] [Abstract][Full Text] [Related]
3. CLK2 inhibition ameliorates autistic features associated with SHANK3 deficiency.
Bidinosti M; Botta P; Krüttner S; Proenca CC; Stoehr N; Bernhard M; Fruh I; Mueller M; Bonenfant D; Voshol H; Carbone W; Neal SJ; McTighe SM; Roma G; Dolmetsch RE; Porter JA; Caroni P; Bouwmeester T; Lüthi A; Galimberti I
Science; 2016 Mar; 351(6278):1199-203. PubMed ID: 26847545
[TBL] [Abstract][Full Text] [Related]
4. Phosphorylation of CLK2 at serine 34 and threonine 127 by AKT controls cell survival after ionizing radiation.
Nam SY; Seo HH; Park HS; An S; Kim JY; Yang KH; Kim CS; Jeong M; Jin YW
J Biol Chem; 2010 Oct; 285(41):31157-63. PubMed ID: 20682768
[TBL] [Abstract][Full Text] [Related]
5. Cdc2-like kinase 2 is an insulin-regulated suppressor of hepatic gluconeogenesis.
Rodgers JT; Haas W; Gygi SP; Puigserver P
Cell Metab; 2010 Jan; 11(1):23-34. PubMed ID: 20074525
[TBL] [Abstract][Full Text] [Related]
6. Selective proteasomal degradation of the B'β subunit of protein phosphatase 2A by the E3 ubiquitin ligase adaptor Kelch-like 15.
Oberg EA; Nifoussi SK; Gingras AC; Strack S
J Biol Chem; 2012 Dec; 287(52):43378-89. PubMed ID: 23135275
[TBL] [Abstract][Full Text] [Related]
7. Regulation of phosphorylation of Thr-308 of Akt, cell proliferation, and survival by the B55alpha regulatory subunit targeting of the protein phosphatase 2A holoenzyme to Akt.
Kuo YC; Huang KY; Yang CH; Yang YS; Lee WY; Chiang CW
J Biol Chem; 2008 Jan; 283(4):1882-92. PubMed ID: 18042541
[TBL] [Abstract][Full Text] [Related]
8. Knockdown of Yin Yang 1 enhances anticancer effects of cisplatin through protein phosphatase 2A-mediated T308 dephosphorylation of AKT.
Zhao L; Li R; Gan YH
Cell Death Dis; 2018 Jul; 9(7):747. PubMed ID: 29970878
[TBL] [Abstract][Full Text] [Related]
9. Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes.
Ugi S; Imamura T; Maegawa H; Egawa K; Yoshizaki T; Shi K; Obata T; Ebina Y; Kashiwagi A; Olefsky JM
Mol Cell Biol; 2004 Oct; 24(19):8778-89. PubMed ID: 15367694
[TBL] [Abstract][Full Text] [Related]
10. PPP2R5B, a regulatory subunit of PP2A, contributes to adipocyte insulin resistance.
Beg M; Srivastava A; Shankar K; Varshney S; Rajan S; Gupta A; Kumar D; Gaikwad AN
Mol Cell Endocrinol; 2016 Dec; 437():97-107. PubMed ID: 27521959
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of B56-containing protein phosphatase 2As by the early response gene IEX-1 leads to control of Akt activity.
Rocher G; Letourneux C; Lenormand P; Porteu F
J Biol Chem; 2007 Feb; 282(8):5468-77. PubMed ID: 17200115
[TBL] [Abstract][Full Text] [Related]
12. The protein phosphatase 2A regulatory subunits B'beta and B'delta mediate sustained TrkA neurotrophin receptor autophosphorylation and neuronal differentiation.
Van Kanegan MJ; Strack S
Mol Cell Biol; 2009 Feb; 29(3):662-74. PubMed ID: 19029245
[TBL] [Abstract][Full Text] [Related]
13. Ciliary transport regulates PDGF-AA/αα signaling via elevated mammalian target of rapamycin signaling and diminished PP2A activity.
Umberger NL; Caspary T
Mol Biol Cell; 2015 Jan; 26(2):350-8. PubMed ID: 25392303
[TBL] [Abstract][Full Text] [Related]
14. The protein phosphatase PP2A-B' subunit Widerborst is a negative regulator of cytoplasmic activated Akt and lipid metabolism in Drosophila.
Vereshchagina N; Ramel MC; Bitoun E; Wilson C
J Cell Sci; 2008 Oct; 121(Pt 20):3383-92. PubMed ID: 18827008
[TBL] [Abstract][Full Text] [Related]
15. ARPP-16 Is a Striatal-Enriched Inhibitor of Protein Phosphatase 2A Regulated by Microtubule-Associated Serine/Threonine Kinase 3 (Mast 3 Kinase).
Andrade EC; Musante V; Horiuchi A; Matsuzaki H; Brody AH; Wu T; Greengard P; Taylor JR; Nairn AC
J Neurosci; 2017 Mar; 37(10):2709-2722. PubMed ID: 28167675
[TBL] [Abstract][Full Text] [Related]
16. Dysregulation of PP2A-Akt interaction contributes to Sucrose non-fermenting related kinase (SNRK) deficiency induced insulin resistance in adipose tissue.
Li J; An R; Lai S; Li L; Liu S; Xu H
Mol Metab; 2019 Oct; 28():26-35. PubMed ID: 31420304
[TBL] [Abstract][Full Text] [Related]
17. Microcystin-LR promotes proliferation by activating Akt/S6K1 pathway and disordering apoptosis and cell cycle associated proteins phosphorylation in HL7702 cells.
Liu J; Wang H; Wang B; Chen T; Wang X; Huang P; Xu L; Guo Z
Toxicol Lett; 2016 Jan; 240(1):214-25. PubMed ID: 26506538
[TBL] [Abstract][Full Text] [Related]
18. The MASTL/PP2A cell cycle kinase-phosphatase module restrains PI3K-Akt activity in an mTORC1-dependent manner.
Sanz-Castillo B; Hurtado B; Vara-Ciruelos D; El Bakkali A; Hermida D; Salvador-Barbero B; Martínez-Alonso D; González-Martínez J; Santiveri C; Campos-Olivas R; Ximénez-Embún P; Muñoz J; Álvarez-Fernández M; Malumbres M
EMBO J; 2023 Jan; 42(2):e110833. PubMed ID: 36354735
[TBL] [Abstract][Full Text] [Related]
19. Inhibition of Protein Phosphatase 2A Sensitizes Mucoepidermoid Carcinoma to Chemotherapy via the PI3K-AKT Pathway in Response to Insulin Stimulus.
Liu L; Wang H; Cui J; Zhang Q; Zhang W; Xu W; Lu H; Liu S; Shen S; Fang F; Li L; Yang W; Zhuang Z; Li J
Cell Physiol Biochem; 2018; 50(1):317-331. PubMed ID: 30282066
[TBL] [Abstract][Full Text] [Related]
20. Distinct protein phosphatase 2A heterotrimers modulate growth factor signaling to extracellular signal-regulated kinases and Akt.
Van Kanegan MJ; Adams DG; Wadzinski BE; Strack S
J Biol Chem; 2005 Oct; 280(43):36029-36. PubMed ID: 16129692
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]