BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

247 related articles for article (PubMed ID: 21331471)

  • 1. Amelioration of lipid-induced insulin resistance in rat skeletal muscle by overexpression of Pgc-1β involves reductions in long-chain acyl-CoA levels and oxidative stress.
    Wright LE; Brandon AE; Hoy AJ; Forsberg GB; Lelliott CJ; Reznick J; Löfgren L; Oscarsson J; Strömstedt M; Cooney GJ; Turner N
    Diabetologia; 2011 Jun; 54(6):1417-26. PubMed ID: 21331471
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Peroxisome proliferator-activated receptor γ coactivator 1β (PGC-1β) improves skeletal muscle mitochondrial function and insulin sensitivity.
    Handschin C
    Diabetologia; 2011 Jun; 54(6):1270-2. PubMed ID: 21461634
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Increased levels of peroxisome proliferator-activated receptor gamma, coactivator 1 alpha (PGC-1alpha) improve lipid utilisation, insulin signalling and glucose transport in skeletal muscle of lean and insulin-resistant obese Zucker rats.
    Benton CR; Holloway GP; Han XX; Yoshida Y; Snook LA; Lally J; Glatz JF; Luiken JJ; Chabowski A; Bonen A
    Diabetologia; 2010 Sep; 53(9):2008-19. PubMed ID: 20490453
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The transcriptional coregulator PGC-1β controls mitochondrial function and anti-oxidant defence in skeletal muscles.
    Gali Ramamoorthy T; Laverny G; Schlagowski AI; Zoll J; Messaddeq N; Bornert JM; Panza S; Ferry A; Geny B; Metzger D
    Nat Commun; 2015 Dec; 6():10210. PubMed ID: 26674215
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Coordinated balancing of muscle oxidative metabolism through PGC-1α increases metabolic flexibility and preserves insulin sensitivity.
    Summermatter S; Troxler H; Santos G; Handschin C
    Biochem Biophys Res Commun; 2011 Apr; 408(1):180-5. PubMed ID: 21501593
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Interactions between the consumption of a high-fat diet and fasting in the regulation of fatty acid oxidation enzyme gene expression: an evaluation of potential mechanisms.
    Frier BC; Jacobs RL; Wright DC
    Am J Physiol Regul Integr Comp Physiol; 2011 Feb; 300(2):R212-21. PubMed ID: 21084676
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Polyphenols prevent ageing-related impairment in skeletal muscle mitochondrial function through decreased reactive oxygen species production.
    Charles AL; Meyer A; Dal-Ros S; Auger C; Keller N; Ramamoorthy TG; Zoll J; Metzger D; Schini-Kerth V; Geny B
    Exp Physiol; 2013 Feb; 98(2):536-45. PubMed ID: 22903980
    [TBL] [Abstract][Full Text] [Related]  

  • 8. High-fat diet-induced reduction of peroxisome proliferator-activated receptor-γ coactivator-1α messenger RNA levels and oxidative capacity in the soleus muscle of rats with metabolic syndrome.
    Nagatomo F; Fujino H; Kondo H; Takeda I; Tsuda K; Ishihara A
    Nutr Res; 2012 Feb; 32(2):144-51. PubMed ID: 22348463
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Modest PGC-1alpha overexpression in muscle in vivo is sufficient to increase insulin sensitivity and palmitate oxidation in subsarcolemmal, not intermyofibrillar, mitochondria.
    Benton CR; Nickerson JG; Lally J; Han XX; Holloway GP; Glatz JF; Luiken JJ; Graham TE; Heikkila JJ; Bonen A
    J Biol Chem; 2008 Feb; 283(7):4228-40. PubMed ID: 18079123
    [TBL] [Abstract][Full Text] [Related]  

  • 10. PGC-1alpha and PGC-1beta have both similar and distinct effects on myofiber switching toward an oxidative phenotype.
    Mortensen OH; Frandsen L; Schjerling P; Nishimura E; Grunnet N
    Am J Physiol Endocrinol Metab; 2006 Oct; 291(4):E807-16. PubMed ID: 16720625
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Overexpression of carnitine palmitoyltransferase-1 in skeletal muscle is sufficient to enhance fatty acid oxidation and improve high-fat diet-induced insulin resistance.
    Bruce CR; Hoy AJ; Turner N; Watt MJ; Allen TL; Carpenter K; Cooney GJ; Febbraio MA; Kraegen EW
    Diabetes; 2009 Mar; 58(3):550-8. PubMed ID: 19073774
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Epinephrine and AICAR-induced PGC-1α mRNA expression is intact in skeletal muscle from rats fed a high-fat diet.
    Frier BC; Wan Z; Williams DB; Stefanson AL; Wright DC
    Am J Physiol Cell Physiol; 2012 Jun; 302(12):C1772-9. PubMed ID: 22496244
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Excess lipid availability increases mitochondrial fatty acid oxidative capacity in muscle: evidence against a role for reduced fatty acid oxidation in lipid-induced insulin resistance in rodents.
    Turner N; Bruce CR; Beale SM; Hoehn KL; So T; Rolph MS; Cooney GJ
    Diabetes; 2007 Aug; 56(8):2085-92. PubMed ID: 17519422
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Paradoxical effects of increased expression of PGC-1alpha on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism.
    Choi CS; Befroy DE; Codella R; Kim S; Reznick RM; Hwang YJ; Liu ZX; Lee HY; Distefano A; Samuel VT; Zhang D; Cline GW; Handschin C; Lin J; Petersen KF; Spiegelman BM; Shulman GI
    Proc Natl Acad Sci U S A; 2008 Dec; 105(50):19926-31. PubMed ID: 19066218
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Improved skeletal muscle oxidative enzyme activity and restoration of PGC-1 alpha and PPAR beta/delta gene expression upon rosiglitazone treatment in obese patients with type 2 diabetes mellitus.
    Mensink M; Hesselink MK; Russell AP; Schaart G; Sels JP; Schrauwen P
    Int J Obes (Lond); 2007 Aug; 31(8):1302-10. PubMed ID: 17310221
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Skeletal muscle mitochondrial and metabolic responses to a high-fat diet in female rats bred for high and low aerobic capacity.
    Naples SP; Borengasser SJ; Rector RS; Uptergrove GM; Morris EM; Mikus CR; Koch LG; Britton SL; Ibdah JA; Thyfault JP
    Appl Physiol Nutr Metab; 2010 Apr; 35(2):151-62. PubMed ID: 20383225
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Enhanced lipid-but not carbohydrate-supported mitochondrial respiration in skeletal muscle of PGC-1α overexpressing mice.
    Hoeks J; Arany Z; Phielix E; Moonen-Kornips E; Hesselink MK; Schrauwen P
    J Cell Physiol; 2012 Mar; 227(3):1026-33. PubMed ID: 21520076
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SIRT1 overexpression in skeletal muscle in vivo induces increased insulin sensitivity and enhanced complex I but not complex II-V functions in individual subsarcolemmal and intermyofibrillar mitochondria.
    Zhang HH; Qin GJ; Li XL; Zhang YH; Du PJ; Zhang PY; Zhao YY; Wu J
    J Physiol Biochem; 2015 Jun; 71(2):177-90. PubMed ID: 25782776
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Long-chain acyl-CoA synthetase 6 regulates lipid synthesis and mitochondrial oxidative capacity in human and rat skeletal muscle.
    Teodoro BG; Sampaio IH; Bomfim LH; Queiroz AL; Silveira LR; Souza AO; Fernandes AM; Eberlin MN; Huang TY; Zheng D; Neufer PD; Cortright RN; Alberici LC
    J Physiol; 2017 Feb; 595(3):677-693. PubMed ID: 27647415
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Peroxisome proliferator-activated receptor (PPAR)-alpha activation lowers muscle lipids and improves insulin sensitivity in high fat-fed rats: comparison with PPAR-gamma activation.
    Ye JM; Doyle PJ; Iglesias MA; Watson DG; Cooney GJ; Kraegen EW
    Diabetes; 2001 Feb; 50(2):411-7. PubMed ID: 11272155
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.