BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

507 related articles for article (PubMed ID: 21338440)

  • 1. Hypoxia activates the hedgehog signaling pathway in a ligand-independent manner by upregulation of Smo transcription in pancreatic cancer.
    Onishi H; Kai M; Odate S; Iwasaki H; Morifuji Y; Ogino T; Morisaki T; Nakashima Y; Katano M
    Cancer Sci; 2011 Jun; 102(6):1144-50. PubMed ID: 21338440
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hypoxia but not normoxia promotes Smoothened transcription through upregulation of RBPJ and Mastermind-like 3 in pancreatic cancer.
    Onishi H; Yamasaki A; Kawamoto M; Imaizumi A; Katano M
    Cancer Lett; 2016 Feb; 371(2):143-50. PubMed ID: 26655998
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Overexpression of smoothened activates the sonic hedgehog signaling pathway in pancreatic cancer-associated fibroblasts.
    Walter K; Omura N; Hong SM; Griffith M; Vincent A; Borges M; Goggins M
    Clin Cancer Res; 2010 Mar; 16(6):1781-9. PubMed ID: 20215540
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hedgehog signaling regulates hypoxia induced epithelial to mesenchymal transition and invasion in pancreatic cancer cells via a ligand-independent manner.
    Lei J; Ma J; Ma Q; Li X; Liu H; Xu Q; Duan W; Sun Q; Xu J; Wu Z; Wu E
    Mol Cancer; 2013 Jun; 12():66. PubMed ID: 23786654
    [TBL] [Abstract][Full Text] [Related]  

  • 5. GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation.
    Nolan-Stevaux O; Lau J; Truitt ML; Chu GC; Hebrok M; Fernández-Zapico ME; Hanahan D
    Genes Dev; 2009 Jan; 23(1):24-36. PubMed ID: 19136624
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Reoxygenation from chronic hypoxia promotes metastatic processes in pancreatic cancer through the Hedgehog signaling.
    Morifuji Y; Onishi H; Iwasaki H; Imaizumi A; Nakano K; Tanaka M; Katano M
    Cancer Sci; 2014 Mar; 105(3):324-33. PubMed ID: 24397700
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hedgehog inhibitor decreases chemosensitivity to 5-fluorouracil and gemcitabine under hypoxic conditions in pancreatic cancer.
    Onishi H; Morifuji Y; Kai M; Suyama K; Iwasaki H; Katano M
    Cancer Sci; 2012 Jul; 103(7):1272-9. PubMed ID: 22486854
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Protein-bound polysaccharide decreases invasiveness and proliferation in pancreatic cancer by inhibition of hedgehog signaling and HIF-1α pathways under hypoxia.
    Onishi H; Morisaki T; Nakao F; Odate S; Morisaki T; Katano M
    Cancer Lett; 2013 Jul; 335(2):289-98. PubMed ID: 23485726
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sonic hedgehog and Gli1 expression predict outcome in resected pancreatic adenocarcinoma.
    Maréchal R; Bachet JB; Calomme A; Demetter P; Delpero JR; Svrcek M; Cros J; Bardier-Dupas A; Puleo F; Monges G; Hammel P; Louvet C; Paye F; Bachelier P; Le Treut YP; Vaillant JC; Sauvanet A; André T; Salmon I; Devière J; Emile JF; Van Laethem JL
    Clin Cancer Res; 2015 Mar; 21(5):1215-24. PubMed ID: 25552484
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Gli1 contributes to the invasiveness of pancreatic cancer through matrix metalloproteinase-9 activation.
    Nagai S; Nakamura M; Yanai K; Wada J; Akiyoshi T; Nakashima H; Ohuchida K; Sato N; Tanaka M; Katano M
    Cancer Sci; 2008 Jul; 99(7):1377-84. PubMed ID: 18410405
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Adenovirus vector-mediated Gli1 siRNA induces growth inhibition and apoptosis in human pancreatic cancer with Smo-dependent or Smo-independent Hh pathway activation in vitro and in vivo.
    Guo J; Gao J; Li Z; Gong Y; Man X; Jin J; Wu H
    Cancer Lett; 2013 Oct; 339(2):185-94. PubMed ID: 23791879
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hedgehog-signaling is upregulated in non-producing human adrenal adenomas and antagonism of hedgehog-signaling inhibits proliferation of NCI-H295R cells and an immortalized primary human adrenal cell line.
    Werminghaus P; Haase M; Hornsby PJ; Schinner S; Schott M; Malendowicz LK; Lammers BJ; Goretzki PE; Müller-Mattheis V; Markus Giessing ; Willenberg HS
    J Steroid Biochem Mol Biol; 2014 Jan; 139():7-15. PubMed ID: 24063979
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sonic Hedgehog-GLI Family Zinc Finger 1 Signaling Pathway Promotes the Growth and Migration of Pancreatic Cancer Cells by Regulating the Transcription of Eukaryotic Translation Initiation Factor 5A2.
    Xu X; Liu H; Zhang H; Dai W; Guo C; Xie C; Wei S; He S; Xu X
    Pancreas; 2015 Nov; 44(8):1252-8. PubMed ID: 26465952
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Curcumin inhibits hypoxia-induced epithelial‑mesenchymal transition in pancreatic cancer cells via suppression of the hedgehog signaling pathway.
    Cao L; Xiao X; Lei J; Duan W; Ma Q; Li W
    Oncol Rep; 2016 Jun; 35(6):3728-34. PubMed ID: 27035865
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cyclopamine reverts acquired chemoresistance and down-regulates cancer stem cell markers in pancreatic cancer cell lines.
    Yao J; An Y; Wie JS; Ji ZL; Lu ZP; Wu JL; Jiang KR; Chen P; Xu ZK; Miao Y
    Swiss Med Wkly; 2011; 141():w13208. PubMed ID: 21630164
    [TBL] [Abstract][Full Text] [Related]  

  • 16. LKB1 inhibits breast cancer partially through repressing the Hedgehog signaling pathway.
    Zhuang Z; Wang K; Cheng X; Qu X; Jiang B; Li Z; Luo J; Shao Z; Duan T
    PLoS One; 2013; 8(7):e67431. PubMed ID: 23861764
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Addiction of pancreatic cancer cells to zinc-finger transcription factor ZIC2.
    Inaguma S; Ito H; Riku M; Ikeda H; Kasai K
    Oncotarget; 2015 Sep; 6(29):28257-68. PubMed ID: 26318045
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hedgehog Signaling Pathway Proteins in Prognosis of Pancreatic Ductal Adenocarcinoma and Its Differentiation From Chronic Pancreatitis.
    Winter K; Dzieniecka M; Strzelczyk J; Wągrowska-Danilewicz M; Danilewicz M; Zatorski H; Małecka-Wojciesko E
    Pancreas; 2022 Mar; 51(3):219-227. PubMed ID: 35584378
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulation of GLI Underlies a Role for BET Bromodomains in Pancreatic Cancer Growth and the Tumor Microenvironment.
    Huang Y; Nahar S; Nakagawa A; Fernandez-Barrena MG; Mertz JA; Bryant BM; Adams CE; Mino-Kenudson M; Von Alt KN; Chang K; Conery AR; Hatton C; Sims RJ; Fernandez-Zapico ME; Wang X; Lillemoe KD; Fernández-Del Castillo C; Warshaw AL; Thayer SP; Liss AS
    Clin Cancer Res; 2016 Aug; 22(16):4259-70. PubMed ID: 27169995
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Upregulation of amplified in breast cancer 1 contributes to pancreatic ductal adenocarcinoma progression and vulnerability to blockage of hedgehog activation.
    Li L; Bao J; Wang H; Lei JH; Peng C; Zeng J; Hao W; Zhang X; Xu X; Yu C; Deng CX; Chen Q
    Theranostics; 2021; 11(4):1672-1689. PubMed ID: 33408774
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 26.