311 related articles for article (PubMed ID: 21339291)
1. TDP-43-induced death is associated with altered regulation of BIM and Bcl-xL and attenuated by caspase-mediated TDP-43 cleavage.
Suzuki H; Lee K; Matsuoka M
J Biol Chem; 2011 Apr; 286(15):13171-83. PubMed ID: 21339291
[TBL] [Abstract][Full Text] [Related]
2. TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration.
Wils H; Kleinberger G; Janssens J; Pereson S; Joris G; Cuijt I; Smits V; Ceuterick-de Groote C; Van Broeckhoven C; Kumar-Singh S
Proc Natl Acad Sci U S A; 2010 Feb; 107(8):3858-63. PubMed ID: 20133711
[TBL] [Abstract][Full Text] [Related]
3. Distinct TDP-43 inclusion morphologies in frontotemporal lobar degeneration with and without amyotrophic lateral sclerosis.
Tan RH; Yang Y; Kim WS; Dobson-Stone C; Kwok JB; Kiernan MC; Halliday GM
Acta Neuropathol Commun; 2017 Oct; 5(1):76. PubMed ID: 29078806
[TBL] [Abstract][Full Text] [Related]
4. The JNK/c-Jun signaling axis contributes to the TDP-43-induced cell death.
Suzuki H; Matsuoka M
Mol Cell Biochem; 2013 Jan; 372(1-2):241-8. PubMed ID: 23001869
[TBL] [Abstract][Full Text] [Related]
5. Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice.
Igaz LM; Kwong LK; Lee EB; Chen-Plotkin A; Swanson E; Unger T; Malunda J; Xu Y; Winton MJ; Trojanowski JQ; Lee VM
J Clin Invest; 2011 Feb; 121(2):726-38. PubMed ID: 21206091
[TBL] [Abstract][Full Text] [Related]
6. Low molecular weight species of TDP-43 generated by abnormal splicing form inclusions in amyotrophic lateral sclerosis and result in motor neuron death.
Xiao S; Sanelli T; Chiang H; Sun Y; Chakrabartty A; Keith J; Rogaeva E; Zinman L; Robertson J
Acta Neuropathol; 2015 Jul; 130(1):49-61. PubMed ID: 25788357
[TBL] [Abstract][Full Text] [Related]
7. The RNA-binding motif 45 (RBM45) protein accumulates in inclusion bodies in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP) patients.
Collins M; Riascos D; Kovalik T; An J; Krupa K; Krupa K; Hood BL; Conrads TP; Renton AE; Traynor BJ; Bowser R
Acta Neuropathol; 2012 Nov; 124(5):717-32. PubMed ID: 22993125
[TBL] [Abstract][Full Text] [Related]
8. The Lysosomal Trafficking Transmembrane Protein 106B Is Linked to Cell Death.
Suzuki H; Matsuoka M
J Biol Chem; 2016 Oct; 291(41):21448-21460. PubMed ID: 27563066
[TBL] [Abstract][Full Text] [Related]
9. p62 overexpression induces TDP-43 cytoplasmic mislocalisation, aggregation and cleavage and neuronal death.
Foster AD; Flynn LL; Cluning C; Cheng F; Davidson JM; Lee A; Polain N; Mejzini R; Farrawell N; Yerbury JJ; Layfield R; Akkari PA; Rea SL
Sci Rep; 2021 Jun; 11(1):11474. PubMed ID: 34075102
[TBL] [Abstract][Full Text] [Related]
10. Pathological hallmarks of amyotrophic lateral sclerosis/frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments.
Swarup V; Phaneuf D; Bareil C; Robertson J; Rouleau GA; Kriz J; Julien JP
Brain; 2011 Sep; 134(Pt 9):2610-26. PubMed ID: 21752789
[TBL] [Abstract][Full Text] [Related]
11. Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity.
Zhang YJ; Xu YF; Cook C; Gendron TF; Roettges P; Link CD; Lin WL; Tong J; Castanedes-Casey M; Ash P; Gass J; Rangachari V; Buratti E; Baralle F; Golde TE; Dickson DW; Petrucelli L
Proc Natl Acad Sci U S A; 2009 May; 106(18):7607-12. PubMed ID: 19383787
[TBL] [Abstract][Full Text] [Related]
12. SecinH3 Attenuates TDP-43 p.Q331K-Induced Neuronal Toxicity by Suppressing Endoplasmic Reticulum Stress and Enhancing Autophagic Flux.
Hu W; Liu X; Wang S; Sun G; Zhao R; Lu H
IUBMB Life; 2019 Feb; 71(2):192-199. PubMed ID: 30376609
[TBL] [Abstract][Full Text] [Related]
13. Possible concurrence of TDP-43, tau and other proteins in amyotrophic lateral sclerosis/frontotemporal lobar degeneration.
Takeda T
Neuropathology; 2018 Feb; 38(1):72-81. PubMed ID: 28960544
[TBL] [Abstract][Full Text] [Related]
14. Elevated expression of TDP-43 in the forebrain of mice is sufficient to cause neurological and pathological phenotypes mimicking FTLD-U.
Tsai KJ; Yang CH; Fang YH; Cho KH; Chien WL; Wang WT; Wu TW; Lin CP; Fu WM; Shen CK
J Exp Med; 2010 Aug; 207(8):1661-73. PubMed ID: 20660618
[TBL] [Abstract][Full Text] [Related]
15. Cytoplasmic poly-GA aggregates impair nuclear import of TDP-43 in C9orf72 ALS/FTLD.
Khosravi B; Hartmann H; May S; Möhl C; Ederle H; Michaelsen M; Schludi MH; Dormann D; Edbauer D
Hum Mol Genet; 2017 Feb; 26(4):790-800. PubMed ID: 28040728
[TBL] [Abstract][Full Text] [Related]
16. TDP-43 toxicity is mediated by the unfolded protein response-unrelated induction of C/EBP homologous protein expression.
Suzuki H; Matsuoka M
J Neurosci Res; 2012 Mar; 90(3):641-7. PubMed ID: 22057717
[TBL] [Abstract][Full Text] [Related]
17. Dual inhibition of Bcl-2 and Bcl-xL strikingly enhances PI3K inhibition-induced apoptosis in human myeloid leukemia cells through a GSK3- and Bim-dependent mechanism.
Rahmani M; Aust MM; Attkisson E; Williams DC; Ferreira-Gonzalez A; Grant S
Cancer Res; 2013 Feb; 73(4):1340-51. PubMed ID: 23243017
[TBL] [Abstract][Full Text] [Related]
18. [The molecular mechanisms of intracellular TDP-43 aggregates].
Nonaka T; Arai T; Hasegawa M
Brain Nerve; 2009 Nov; 61(11):1292-300. PubMed ID: 19938686
[TBL] [Abstract][Full Text] [Related]
19. Expression of TDP-43 C-terminal Fragments in Vitro Recapitulates Pathological Features of TDP-43 Proteinopathies.
Igaz LM; Kwong LK; Chen-Plotkin A; Winton MJ; Unger TL; Xu Y; Neumann M; Trojanowski JQ; Lee VM
J Biol Chem; 2009 Mar; 284(13):8516-24. PubMed ID: 19164285
[TBL] [Abstract][Full Text] [Related]
20. Translocation of Bim to the endoplasmic reticulum (ER) mediates ER stress signaling for activation of caspase-12 during ER stress-induced apoptosis.
Morishima N; Nakanishi K; Tsuchiya K; Shibata T; Seiwa E
J Biol Chem; 2004 Nov; 279(48):50375-81. PubMed ID: 15452118
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
