136 related articles for article (PubMed ID: 21340509)
1. Characterization of dequalinium as a XIAP antagonist that targets the BIR2 domain.
Orzáez M; Gortat A; Sancho M; Carbajo RJ; Pineda-Lucena A; Palacios-Rodríguez Y; Pérez-Payá E
Apoptosis; 2011 May; 16(5):460-7. PubMed ID: 21340509
[TBL] [Abstract][Full Text] [Related]
2. Design and characterization of bivalent Smac-based peptides as antagonists of XIAP and development and validation of a fluorescence polarization assay for XIAP containing both BIR2 and BIR3 domains.
Nikolovska-Coleska Z; Meagher JL; Jiang S; Kawamoto SA; Gao W; Yi H; Qin D; Roller PP; Stuckey JA; Wang S
Anal Biochem; 2008 Mar; 374(1):87-98. PubMed ID: 18023397
[TBL] [Abstract][Full Text] [Related]
3. BIR2 domain of XIAP plays a marginal role in inhibition of executioner caspases.
Abhari BA; Davoodi J
Int J Biol Macromol; 2010 Apr; 46(3):337-41. PubMed ID: 20060411
[TBL] [Abstract][Full Text] [Related]
4. Optimization of benzodiazepinones as selective inhibitors of the X-linked inhibitor of apoptosis protein (XIAP) second baculovirus IAP repeat (BIR2) domain.
Kester RF; Donnell AF; Lou Y; Remiszewski SW; Lombardo LJ; Chen S; Le NT; Lo J; Moliterni JA; Han X; Hogg JH; Liang W; Michoud C; Rupert KC; Mischke S; Le K; Weisel M; Janson CA; Lukacs CM; Fretland AJ; Hong K; Polonskaia A; Gao L; Li S; Solis DS; Aguilar D; Tardell C; Dvorozniak M; Tannu S; Lee EC; Schutt AD; Goggin B
J Med Chem; 2013 Oct; 56(20):7788-803. PubMed ID: 24093940
[TBL] [Abstract][Full Text] [Related]
5. Identification of mammalian mitochondrial proteins that interact with IAPs via N-terminal IAP binding motifs.
Verhagen AM; Kratina TK; Hawkins CJ; Silke J; Ekert PG; Vaux DL
Cell Death Differ; 2007 Feb; 14(2):348-57. PubMed ID: 16794601
[TBL] [Abstract][Full Text] [Related]
6. Cell-penetrating peptide-conjugated XIAP-inhibitory cyclic hexapeptides enter into Jurkat cells and inhibit cell proliferation.
Sasaki Y; Minamizawa M; Ambo A; Sugawara S; Ogawa Y; Nitta K
FEBS J; 2008 Dec; 275(23):6011-21. PubMed ID: 19016849
[TBL] [Abstract][Full Text] [Related]
7. Benzazepinones and benzoxazepinones as antagonists of inhibitor of apoptosis proteins (IAPs) selective for the second baculovirus IAP repeat (BIR2) domain.
Donnell AF; Michoud C; Rupert KC; Han X; Aguilar D; Frank KB; Fretland AJ; Gao L; Goggin B; Hogg JH; Hong K; Janson CA; Kester RF; Kong N; Le K; Li S; Liang W; Lombardo LJ; Lou Y; Lukacs CM; Mischke S; Moliterni JA; Polonskaia A; Schutt AD; Solis DS; Specian A; Taylor RT; Weisel M; Remiszewski SW
J Med Chem; 2013 Oct; 56(20):7772-87. PubMed ID: 24083782
[TBL] [Abstract][Full Text] [Related]
8. A mechanistic insight into SMAC peptide interference with XIAP-Bir2 inhibition of executioner caspases.
Abhari BA; Davoodi J
J Mol Biol; 2008 Sep; 381(3):645-54. PubMed ID: 18619610
[TBL] [Abstract][Full Text] [Related]
9. Alpha-fetoprotein antagonizes X-linked inhibitor of apoptosis protein anticaspase activity and disrupts XIAP-caspase interaction.
Dudich E; Semenkova L; Dudich I; Denesyuk A; Tatulov E; Korpela T
FEBS J; 2006 Aug; 273(16):3837-49. PubMed ID: 16869888
[TBL] [Abstract][Full Text] [Related]
10. Targeting the X-linked inhibitor of apoptosis protein through 4-substituted azabicyclo[5.3.0]alkane smac mimetics. Structure, activity, and recognition principles.
Mastrangelo E; Cossu F; Milani M; Sorrentino G; Lecis D; Delia D; Manzoni L; Drago C; Seneci P; Scolastico C; Rizzo V; Bolognesi M
J Mol Biol; 2008 Dec; 384(3):673-89. PubMed ID: 18851976
[TBL] [Abstract][Full Text] [Related]
11. NMR structure and mutagenesis of the inhibitor-of-apoptosis protein XIAP.
Sun C; Cai M; Gunasekera AH; Meadows RP; Wang H; Chen J; Zhang H; Wu W; Xu N; Ng SC; Fesik SW
Nature; 1999 Oct; 401(6755):818-22. PubMed ID: 10548111
[TBL] [Abstract][Full Text] [Related]
12. Molecular interaction between HAX-1 and XIAP inhibits apoptosis.
Kang YJ; Jang M; Park YK; Kang S; Bae KH; Cho S; Lee CK; Park BC; Chi SW; Park SG
Biochem Biophys Res Commun; 2010 Mar; 393(4):794-9. PubMed ID: 20171186
[TBL] [Abstract][Full Text] [Related]
13. Structural basis for bivalent Smac-mimetics recognition in the IAP protein family.
Cossu F; Milani M; Mastrangelo E; Vachette P; Servida F; Lecis D; Canevari G; Delia D; Drago C; Rizzo V; Manzoni L; Seneci P; Scolastico C; Bolognesi M
J Mol Biol; 2009 Sep; 392(3):630-44. PubMed ID: 19393243
[TBL] [Abstract][Full Text] [Related]
14. In silico discovery of acylated flavonol monorhamnosides from Eriobotrya japonica as natural, small-molecular weight inhibitors of XIAP BIR3.
Pfisterer PH; Shen C; Nikolovska-Coleska Z; Schyschka L; Schuster D; Rudy A; Wolber G; Vollmar AM; Rollinger JM; Stuppner H
Bioorg Med Chem; 2011 Jan; 19(2):1002-9. PubMed ID: 21087868
[TBL] [Abstract][Full Text] [Related]
15. Discovery of potent antagonists of the antiapoptotic protein XIAP for the treatment of cancer.
Oost TK; Sun C; Armstrong RC; Al-Assaad AS; Betz SF; Deckwerth TL; Ding H; Elmore SW; Meadows RP; Olejniczak ET; Oleksijew A; Oltersdorf T; Rosenberg SH; Shoemaker AR; Tomaselli KJ; Zou H; Fesik SW
J Med Chem; 2004 Aug; 47(18):4417-26. PubMed ID: 15317454
[TBL] [Abstract][Full Text] [Related]
16. Structural basis of caspase inhibition by XIAP: differential roles of the linker versus the BIR domain.
Huang Y; Park YC; Rich RL; Segal D; Myszka DG; Wu H
Cell; 2001 Mar; 104(5):781-90. PubMed ID: 11257231
[TBL] [Abstract][Full Text] [Related]
17. Topotecan triggers apoptosis in p53-deficient cells by forcing degradation of XIAP and survivin thereby activating caspase-3-mediated Bid cleavage.
Tomicic MT; Christmann M; Kaina B
J Pharmacol Exp Ther; 2010 Jan; 332(1):316-25. PubMed ID: 19812371
[TBL] [Abstract][Full Text] [Related]
18. Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain.
Liu Z; Sun C; Olejniczak ET; Meadows RP; Betz SF; Oost T; Herrmann J; Wu JC; Fesik SW
Nature; 2000 Dec 21-28; 408(6815):1004-8. PubMed ID: 11140637
[TBL] [Abstract][Full Text] [Related]
19. Building homogeneous time-resolved fluorescence resonance energy transfer assays for characterization of bivalent inhibitors of an inhibitor of apoptosis protein target.
Chaudhry C; Davis J; Zhang Y; Posy S; Lei M; Shen H; Yan C; Devaux B; Zhang L; Blat Y; Metzler W; Borzilleri RM; Talbott RL
Anal Biochem; 2016 Mar; 497():8-17. PubMed ID: 26743718
[TBL] [Abstract][Full Text] [Related]
20. Sensitization of human bladder tumor cells to TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis with a small molecule IAP antagonist.
Griffith TS; Kucaba TA; O'Donnell MA; Burns J; Benetatos C; McKinlay MA; Condon S; Chunduru S
Apoptosis; 2011 Jan; 16(1):13-26. PubMed ID: 20734142
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
