BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

180 related articles for article (PubMed ID: 21345796)

  • 1. B-Raf associates with and activates the NHE1 isoform of the Na+/H+ exchanger.
    Karki P; Li X; Schrama D; Fliegel L
    J Biol Chem; 2011 Apr; 286(15):13096-105. PubMed ID: 21345796
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activation of the Na
    Li X; Augustine A; Sun D; Li L; Fliegel L
    J Mol Cell Cardiol; 2016 Oct; 99():65-75. PubMed ID: 27555478
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mitochondrial localization and regulation of BRAFV600E in thyroid cancer: a clinically used RAF inhibitor is unable to block the mitochondrial activities of BRAFV600E.
    Lee MH; Lee SE; Kim DW; Ryu MJ; Kim SJ; Kim SJ; Kim YK; Park JH; Kweon GR; Kim JM; Lee JU; De Falco V; Jo YS; Shong M
    J Clin Endocrinol Metab; 2011 Jan; 96(1):E19-30. PubMed ID: 20926530
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Two G protein-coupled receptors activate Na+/H+ exchanger isoform 1 in Chinese hamster lung fibroblasts through an ERK-dependent pathway.
    Wallert MA; Thronson HL; Korpi NL; Olmschenk SM; McCoy AC; Funfar MR; Provost JJ
    Cell Signal; 2005 Feb; 17(2):231-42. PubMed ID: 15494214
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cyclic AMP/PKA-dependent paradoxical activation of Raf/MEK/ERK signaling in polycystin-2 defective mice treated with sorafenib.
    Spirli C; Morell CM; Locatelli L; Okolicsanyi S; Ferrero C; Kim AK; Fabris L; Fiorotto R; Strazzabosco M
    Hepatology; 2012 Dec; 56(6):2363-74. PubMed ID: 22653837
    [TBL] [Abstract][Full Text] [Related]  

  • 6. C-Raf inhibits MAPK activation and transformation by B-Raf(V600E).
    Karreth FA; DeNicola GM; Winter SP; Tuveson DA
    Mol Cell; 2009 Nov; 36(3):477-86. PubMed ID: 19917255
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phenylephrine and sustained acidosis activate the neonatal rat cardiomyocyte Na+/H+ exchanger through phosphorylation of amino acids Ser770 and Ser771.
    Coccaro E; Karki P; Cojocaru C; Fliegel L
    Am J Physiol Heart Circ Physiol; 2009 Aug; 297(2):H846-58. PubMed ID: 19542484
    [TBL] [Abstract][Full Text] [Related]  

  • 8. pH dependence of melanoma cell migration: protons extruded by NHE1 dominate protons of the bulk solution.
    Stüwe L; Müller M; Fabian A; Waning J; Mally S; Noël J; Schwab A; Stock C
    J Physiol; 2007 Dec; 585(Pt 2):351-60. PubMed ID: 17916606
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Apoptosis of human melanoma cells induced by inhibition of B-RAFV600E involves preferential splicing of bimS.
    Jiang CC; Lai F; Tay KH; Croft A; Rizos H; Becker TM; Yang F; Liu H; Thorne RF; Hersey P; Zhang XD
    Cell Death Dis; 2010 Sep; 1(9):e69. PubMed ID: 21364673
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Distinct requirement for an intact dimer interface in wild-type, V600E and kinase-dead B-Raf signalling.
    Röring M; Herr R; Fiala GJ; Heilmann K; Braun S; Eisenhardt AE; Halbach S; Capper D; von Deimling A; Schamel WW; Saunders DN; Brummer T
    EMBO J; 2012 May; 31(11):2629-47. PubMed ID: 22510884
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Stimulation of astrocyte Na+/H+ exchange activity in response to in vitro ischemia depends in part on activation of ERK1/2.
    Kintner DB; Look A; Shull GE; Sun D
    Am J Physiol Cell Physiol; 2005 Oct; 289(4):C934-45. PubMed ID: 15901600
    [TBL] [Abstract][Full Text] [Related]  

  • 12. [Pt(O,O'-acac)(γ-acac)(DMS)] alters SH-SY5Y cell migration and invasion by the inhibition of Na+/H+ exchanger isoform 1 occurring through a PKC-ε/ERK/mTOR Pathway.
    Muscella A; Vetrugno C; Calabriso N; Cossa LG; De Pascali SA; Fanizzi FP; Marsigliante S
    PLoS One; 2014; 9(11):e112186. PubMed ID: 25372487
    [TBL] [Abstract][Full Text] [Related]  

  • 13. C-Raf is associated with disease progression and cell proliferation in a subset of melanomas.
    Jilaveanu LB; Zito CR; Aziz SA; Conrad PJ; Schmitz JC; Sznol M; Camp RL; Rimm DL; Kluger HM
    Clin Cancer Res; 2009 Sep; 15(18):5704-13. PubMed ID: 19737955
    [TBL] [Abstract][Full Text] [Related]  

  • 14. RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E).
    Poulikakos PI; Persaud Y; Janakiraman M; Kong X; Ng C; Moriceau G; Shi H; Atefi M; Titz B; Gabay MT; Salton M; Dahlman KB; Tadi M; Wargo JA; Flaherty KT; Kelley MC; Misteli T; Chapman PB; Sosman JA; Graeber TG; Ribas A; Lo RS; Rosen N; Solit DB
    Nature; 2011 Nov; 480(7377):387-90. PubMed ID: 22113612
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Limited Proteolysis Combined with Stable Isotope Labeling Reveals Conformational Changes in Protein (Pseudo)kinases upon Binding Small Molecules.
    Di Michele M; Stes E; Vandermarliere E; Arora R; Astorga-Wells J; Vandenbussche J; van Heerde E; Zubarev R; Bonnet P; Linders JT; Jacoby E; Brehmer D; Martens L; Gevaert K
    J Proteome Res; 2015 Oct; 14(10):4179-93. PubMed ID: 26293246
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Differential inhibitory effects of two Raf-targeting drugs, sorafenib and PLX4720, on the growth of multidrug-resistant cells.
    Eum KH; Ahn SK; Kang H; Lee M
    Mol Cell Biochem; 2013 Jan; 372(1-2):65-74. PubMed ID: 22941213
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Glutamatergic pathway targeting in melanoma: single-agent and combinatorial therapies.
    Lee HJ; Wall BA; Wangari-Talbot J; Shin SS; Rosenberg S; Chan JL; Namkoong J; Goydos JS; Chen S
    Clin Cancer Res; 2011 Nov; 17(22):7080-92. PubMed ID: 21844014
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sorafenib inhibits growth and mitogen-activated protein kinase signaling in malignant peripheral nerve sheath cells.
    Ambrosini G; Cheema HS; Seelman S; Teed A; Sambol EB; Singer S; Schwartz GK
    Mol Cancer Ther; 2008 Apr; 7(4):890-6. PubMed ID: 18413802
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Oncogenic RAF: a brief history of time.
    Solit D; Rosen N
    Pigment Cell Melanoma Res; 2010 Dec; 23(6):760-2. PubMed ID: 20973931
    [No Abstract]   [Full Text] [Related]  

  • 20. Apoptosis-induced alkalinization by the Na+/H+ exchanger isoform 1 is mediated through phosphorylation of amino acids Ser726 and Ser729.
    Grenier AL; Abu-ihweij K; Zhang G; Ruppert SM; Boohaker R; Slepkov ER; Pridemore K; Ren JJ; Fliegel L; Khaled AR
    Am J Physiol Cell Physiol; 2008 Oct; 295(4):C883-96. PubMed ID: 18701649
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.