533 related articles for article (PubMed ID: 21345977)
1. Curcumin inhibits cystogenesis by simultaneous interference of multiple signaling pathways: in vivo evidence from a Pkd1-deletion model.
Leonhard WN; van der Wal A; Novalic Z; Kunnen SJ; Gansevoort RT; Breuning MH; de Heer E; Peters DJ
Am J Physiol Renal Physiol; 2011 May; 300(5):F1193-202. PubMed ID: 21345977
[TBL] [Abstract][Full Text] [Related]
2. Toxic tubular injury in kidneys from Pkd1-deletion mice accelerates cystogenesis accompanied by dysregulated planar cell polarity and canonical Wnt signaling pathways.
Happé H; Leonhard WN; van der Wal A; van de Water B; Lantinga-van Leeuwen IS; Breuning MH; de Heer E; Peters DJ
Hum Mol Genet; 2009 Jul; 18(14):2532-42. PubMed ID: 19401297
[TBL] [Abstract][Full Text] [Related]
3. Rapamycin-mediated suppression of renal cyst expansion in del34 Pkd1-/- mutant mouse embryos: an investigation of the feasibility of renal cyst prevention in the foetus.
Stayner C; Shields J; Slobbe L; Shillingford JM; Weimbs T; Eccles MR
Nephrology (Carlton); 2012 Nov; 17(8):739-47. PubMed ID: 22725947
[TBL] [Abstract][Full Text] [Related]
4. Comparison of folate-conjugated rapamycin versus unconjugated rapamycin in an orthologous mouse model of polycystic kidney disease.
Kipp KR; Kruger SL; Schimmel MF; Parker N; Shillingford JM; Leamon CP; Weimbs T
Am J Physiol Renal Physiol; 2018 Aug; 315(2):F395-F405. PubMed ID: 29717938
[TBL] [Abstract][Full Text] [Related]
5. The regulatory 1α subunit of protein kinase A modulates renal cystogenesis.
Ye H; Wang X; Constans MM; Sussman CR; Chebib FT; Irazabal MV; Young WF; Harris PC; Kirschner LS; Torres VE
Am J Physiol Renal Physiol; 2017 Sep; 313(3):F677-F686. PubMed ID: 28615245
[TBL] [Abstract][Full Text] [Related]
6. Double inhibition of cAMP and mTOR signalling may potentiate the reduction of cell growth in ADPKD cells.
de Stephanis L; Bonon A; Varani K; Lanza G; Gafà R; Pinton P; Pema M; Somlo S; Boletta A; Aguiari G
Clin Exp Nephrol; 2017 Apr; 21(2):203-211. PubMed ID: 27278932
[TBL] [Abstract][Full Text] [Related]
7. Pkd1 regulates immortalized proliferation of renal tubular epithelial cells through p53 induction and JNK activation.
Nishio S; Hatano M; Nagata M; Horie S; Koike T; Tokuhisa T; Mochizuki T
J Clin Invest; 2005 Apr; 115(4):910-8. PubMed ID: 15761494
[TBL] [Abstract][Full Text] [Related]
8. Progressive renal distortion by multiple cysts in transgenic mice expressing artificial microRNAs against Pkd1.
Wang E; Hsieh-Li HM; Chiou YY; Chien YL; Ho HH; Chin HJ; Wang CK; Liang SC; Jiang ST
J Pathol; 2010 Nov; 222(3):238-48. PubMed ID: 20814903
[TBL] [Abstract][Full Text] [Related]
9. Elevated TGFbeta-Smad signalling in experimental Pkd1 models and human patients with polycystic kidney disease.
Hassane S; Leonhard WN; van der Wal A; Hawinkels LJ; Lantinga-van Leeuwen IS; ten Dijke P; Breuning MH; de Heer E; Peters DJ
J Pathol; 2010 Sep; 222(1):21-31. PubMed ID: 20549648
[TBL] [Abstract][Full Text] [Related]
10. Overexpression of PKD1 causes polycystic kidney disease.
Thivierge C; Kurbegovic A; Couillard M; Guillaume R; Coté O; Trudel M
Mol Cell Biol; 2006 Feb; 26(4):1538-48. PubMed ID: 16449663
[TBL] [Abstract][Full Text] [Related]
11. Autophagy activators suppress cystogenesis in an autosomal dominant polycystic kidney disease model.
Zhu P; Sieben CJ; Xu X; Harris PC; Lin X
Hum Mol Genet; 2017 Jan; 26(1):158-172. PubMed ID: 28007903
[TBL] [Abstract][Full Text] [Related]
12. Rapamycin treatment dose-dependently improves the cystic kidney in a new ADPKD mouse model via the mTORC1 and cell-cycle-associated CDK1/cyclin axis.
Li A; Fan S; Xu Y; Meng J; Shen X; Mao J; Zhang L; Zhang X; Moeckel G; Wu D; Wu G; Liang C
J Cell Mol Med; 2017 Aug; 21(8):1619-1635. PubMed ID: 28244683
[TBL] [Abstract][Full Text] [Related]
13. Inhibition of mTOR with sirolimus slows disease progression in Han:SPRD rats with autosomal dominant polycystic kidney disease (ADPKD).
Wahl PR; Serra AL; Le Hir M; Molle KD; Hall MN; Wüthrich RP
Nephrol Dial Transplant; 2006 Mar; 21(3):598-604. PubMed ID: 16221708
[TBL] [Abstract][Full Text] [Related]
14. Ablation of Long Noncoding RNA Hoxb3os Exacerbates Cystogenesis in Mouse Polycystic Kidney Disease.
Weisser I; Eckberg K; D'Amico S; Buttram D; Aboudehen K
J Am Soc Nephrol; 2024 Jan; 35(1):41-55. PubMed ID: 37953472
[TBL] [Abstract][Full Text] [Related]
15. Altered Hippo signalling in polycystic kidney disease.
Happé H; van der Wal AM; Leonhard WN; Kunnen SJ; Breuning MH; de Heer E; Peters DJ
J Pathol; 2011 May; 224(1):133-42. PubMed ID: 21381034
[TBL] [Abstract][Full Text] [Related]
16. Attenuation of accelerated renal cystogenesis in Pkd1 mice by renin-angiotensin system blockade.
Fitzgibbon WR; Dang Y; Bunni MA; Baicu CF; Zile MR; Mullick AE; Saigusa T
Am J Physiol Renal Physiol; 2018 Feb; 314(2):F210-F218. PubMed ID: 29021226
[TBL] [Abstract][Full Text] [Related]
17. A study of sirolimus and mTOR kinase inhibitor in a hypomorphic
Holditch SJ; Brown CN; Atwood DJ; Lombardi AM; Nguyen KN; Toll HW; Hopp K; Edelstein CL
Am J Physiol Renal Physiol; 2019 Jul; 317(1):F187-F196. PubMed ID: 31042058
[TBL] [Abstract][Full Text] [Related]
18. Lysine methyltransferase SMYD2 promotes cyst growth in autosomal dominant polycystic kidney disease.
Li LX; Fan LX; Zhou JX; Grantham JJ; Calvet JP; Sage J; Li X
J Clin Invest; 2017 Jun; 127(7):2751-2764. PubMed ID: 28604386
[TBL] [Abstract][Full Text] [Related]
19. Defects in cell polarity underlie TSC and ADPKD-associated cystogenesis.
Bonnet CS; Aldred M; von Ruhland C; Harris R; Sandford R; Cheadle JP
Hum Mol Genet; 2009 Jun; 18(12):2166-76. PubMed ID: 19321600
[TBL] [Abstract][Full Text] [Related]
20. Pax2 gene dosage influences cystogenesis in autosomal dominant polycystic kidney disease.
Stayner C; Iglesias DM; Goodyer PR; Ellis L; Germino G; Zhou J; Eccles MR
Hum Mol Genet; 2006 Dec; 15(24):3520-8. PubMed ID: 17082250
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
