These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

152 related articles for article (PubMed ID: 21347367)

  • 1. Two TPX2-dependent switches control the activity of Aurora A.
    Xu X; Wang X; Xiao Z; Li Y; Wang Y
    PLoS One; 2011 Feb; 6(2):e16757. PubMed ID: 21347367
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ashwagandha derived withanone targets TPX2-Aurora A complex: computational and experimental evidence to its anticancer activity.
    Grover A; Singh R; Shandilya A; Priyandoko D; Agrawal V; Bisaria VS; Wadhwa R; Kaul SC; Sundar D
    PLoS One; 2012; 7(1):e30890. PubMed ID: 22303466
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A novel mechanism for activation of the protein kinase Aurora A.
    Eyers PA; Erikson E; Chen LG; Maller JL
    Curr Biol; 2003 Apr; 13(8):691-7. PubMed ID: 12699628
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural basis of Aurora-A activation by TPX2 at the mitotic spindle.
    Bayliss R; Sardon T; Vernos I; Conti E
    Mol Cell; 2003 Oct; 12(4):851-62. PubMed ID: 14580337
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural basis of specific binding between Aurora A and TPX2 by molecular dynamics simulations.
    Cheng Y; Zhang F; Chen Q; Gao J; Cui W; Ji M; Tung CH
    J Chem Inf Model; 2011 Oct; 51(10):2626-35. PubMed ID: 21919471
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Control of Aurora-A stability through interaction with TPX2.
    Giubettini M; Asteriti IA; Scrofani J; De Luca M; Lindon C; Lavia P; Guarguaglini G
    J Cell Sci; 2011 Jan; 124(Pt 1):113-22. PubMed ID: 21147853
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Regulation of Xenopus Aurora A activation by TPX2.
    Eyers PA; Maller JL
    J Biol Chem; 2004 Mar; 279(10):9008-15. PubMed ID: 14701852
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Activation of Aurora-A kinase by protein partner binding and phosphorylation are independent and synergistic.
    Dodson CA; Bayliss R
    J Biol Chem; 2012 Jan; 287(2):1150-7. PubMed ID: 22094468
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Abrogation of AuroraA-TPX2 by novel natural inhibitors: molecular dynamics-based mechanistic analysis.
    Gupta A; Jain R; Wahi D; Goyal S; Jamal S; Grover A
    J Recept Signal Transduct Res; 2015; 35(6):626-33. PubMed ID: 26390942
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ran modulates spindle assembly by regulating a subset of TPX2 and Kid activities including Aurora A activation.
    Trieselmann N; Armstrong S; Rauw J; Wilde A
    J Cell Sci; 2003 Dec; 116(Pt 23):4791-8. PubMed ID: 14600264
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The Aurora A and Aurora B protein kinases: a single amino acid difference controls intrinsic activity and activation by TPX2.
    Eyers PA; Churchill ME; Maller JL
    Cell Cycle; 2005 Jun; 4(6):784-9. PubMed ID: 15908779
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Protein phosphatase 6 regulates mitotic spindle formation by controlling the T-loop phosphorylation state of Aurora A bound to its activator TPX2.
    Zeng K; Bastos RN; Barr FA; Gruneberg U
    J Cell Biol; 2010 Dec; 191(7):1315-32. PubMed ID: 21187329
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Binding of TPX2 to Aurora A alters substrate and inhibitor interactions.
    Anderson K; Yang J; Koretke K; Nurse K; Calamari A; Kirkpatrick RB; Patrick D; Silva D; Tummino PJ; Copeland RA; Lai Z
    Biochemistry; 2007 Sep; 46(36):10287-95. PubMed ID: 17705509
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A functional interplay between Aurora-A, Plk1 and TPX2 at spindle poles: Plk1 controls centrosomal localization of Aurora-A and TPX2 spindle association.
    De Luca M; Lavia P; Guarguaglini G
    Cell Cycle; 2006 Feb; 5(3):296-303. PubMed ID: 16418575
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Determinants for Aurora-A activation and Aurora-B discrimination by TPX2.
    Bayliss R; Sardon T; Ebert J; Lindner D; Vernos I; Conti E
    Cell Cycle; 2004 Apr; 3(4):404-7. PubMed ID: 14752279
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A.
    Bird AW; Hyman AA
    J Cell Biol; 2008 Jul; 182(2):289-300. PubMed ID: 18663142
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Phosphorylation of TPX2 by Plx1 enhances activation of Aurora A.
    Eckerdt F; Pascreau G; Phistry M; Lewellyn AL; DePaoli-Roach AA; Maller JL
    Cell Cycle; 2009 Aug; 8(15):2413-9. PubMed ID: 19556869
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches.
    McIntyre PJ; Collins PM; Vrzal L; Birchall K; Arnold LH; Mpamhanga C; Coombs PJ; Burgess SG; Richards MW; Winter A; Veverka V; Delft FV; Merritt A; Bayliss R
    ACS Chem Biol; 2017 Nov; 12(11):2906-2914. PubMed ID: 29045126
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A cancer-associated aurora A mutant is mislocalized and misregulated due to loss of interaction with TPX2.
    Bibby RA; Tang C; Faisal A; Drosopoulos K; Lubbe S; Houlston R; Bayliss R; Linardopoulos S
    J Biol Chem; 2009 Nov; 284(48):33177-84. PubMed ID: 19801554
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A TPX2 Proteomimetic Has Enhanced Affinity for Aurora-A Due to Hydrocarbon Stapling of a Helix.
    Rennie YK; McIntyre PJ; Akindele T; Bayliss R; Jamieson AG
    ACS Chem Biol; 2016 Dec; 11(12):3383-3390. PubMed ID: 27775325
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.