BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

263 related articles for article (PubMed ID: 21347502)

  • 1. Promoting the formation and stabilization of human telomeric G-quadruplex DNA, inhibition of telomerase and cytotoxicity by phenanthroline derivatives.
    Wang L; Wen Y; Liu J; Zhou J; Li C; Wei C
    Org Biomol Chem; 2011 Apr; 9(8):2648-53. PubMed ID: 21347502
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and binding studies of novel di-substituted phenanthroline compounds with genomic promoter and human telomeric DNA G-quadruplexes.
    Wei C; Wang Y; Zhang M
    Org Biomol Chem; 2013 Apr; 11(14):2355-64. PubMed ID: 23429572
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Selective recognition of G-qQuadruplex telomeric DNA by a bis(quinacridine) macrocycle.
    Teulade-Fichou MP; Carrasco C; Guittat L; Bailly C; Alberti P; Mergny JL; David A; Lehn JM; Wilson WD
    J Am Chem Soc; 2003 Apr; 125(16):4732-40. PubMed ID: 12696891
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Studies on characterization, telomerase inhibitory properties and G-quadruplex binding of η6-arene ruthenium complexes with 1,10-phenanthroline-derived ligands.
    Sun D; Zhang R; Yuan F; Liu D; Zhou Y; Liu J
    Dalton Trans; 2012 Feb; 41(6):1734-41. PubMed ID: 22159049
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Disubstituted 2-phenyl-benzopyranopyrimidine derivatives as a new type of highly selective ligands for telomeric G-quadruplex DNA.
    Wu WB; Chen SH; Hou JQ; Tan JH; Ou TM; Huang SL; Li D; Gu LQ; Huang ZS
    Org Biomol Chem; 2011 Apr; 9(8):2975-86. PubMed ID: 21373680
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeting telomeric G-quadruplexes with the ruthenium(II) complexes [Ru(bpy)(2)(ptpn)](2+) and [Ru(phen)(2)(ptpn)](2+).
    Chen X; Wu JH; Lai YW; Zhao R; Chao H; Ji LN
    Dalton Trans; 2013 Apr; 42(13):4386-97. PubMed ID: 23400220
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 4-(1H-imidazo[4,5-f]-1,10-phenanthrolin-2-yl)phenol-based G-quadruplex DNA binding agents: telomerase inhibition, cytotoxicity and DNA-binding studies.
    Wei CY; Wang JH; Wen Y; Liu J; Wang LH
    Bioorg Med Chem; 2013 Jun; 21(11):3379-87. PubMed ID: 23611765
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Symmetrical bisbenzimidazoles with benzenediyl spacer: the role of the shape of the ligand on the stabilization and structural alterations in telomeric G-quadruplex DNA and telomerase inhibition.
    Bhattacharya S; Chaudhuri P; Jain AK; Paul A
    Bioconjug Chem; 2010 Jul; 21(7):1148-59. PubMed ID: 20536245
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 9-Substituted berberine derivatives as G-quadruplex stabilizing ligands in telomeric DNA.
    Zhang WJ; Ou TM; Lu YJ; Huang YY; Wu WB; Huang ZS; Zhou JL; Wong KY; Gu LQ
    Bioorg Med Chem; 2007 Aug; 15(16):5493-501. PubMed ID: 17574421
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and evaluation of 9-O-substituted berberine derivatives containing aza-aromatic terminal group as highly selective telomeric G-quadruplex stabilizing ligands.
    Ma Y; Ou TM; Tan JH; Hou JQ; Huang SL; Gu LQ; Huang ZS
    Bioorg Med Chem Lett; 2009 Jul; 19(13):3414-7. PubMed ID: 19477640
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Rational design of acridine-based ligands with selectivity for human telomeric quadruplexes.
    Sparapani S; Haider SM; Doria F; Gunaratnam M; Neidle S
    J Am Chem Soc; 2010 Sep; 132(35):12263-72. PubMed ID: 20718414
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Fluorescence-based melting assays for studying quadruplex ligands.
    De Cian A; Guittat L; Kaiser M; Saccà B; Amrane S; Bourdoncle A; Alberti P; Teulade-Fichou MP; Lacroix L; Mergny JL
    Methods; 2007 Jun; 42(2):183-95. PubMed ID: 17472900
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Stabilization of G-quadruplex DNA, inhibition of telomerase activity and live cell imaging studies of chiral ruthenium(II) complexes.
    Sun D; Liu Y; Liu D; Zhang R; Yang X; Liu J
    Chemistry; 2012 Apr; 18(14):4285-95. PubMed ID: 22367788
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 5-N-methylated quindoline derivatives as telomeric g-quadruplex stabilizing ligands: effects of 5-N positive charge on quadruplex binding affinity and cell proliferation.
    Lu YJ; Ou TM; Tan JH; Hou JQ; Shao WY; Peng D; Sun N; Wang XD; Wu WB; Bu XZ; Huang ZS; Ma DL; Wong KY; Gu LQ
    J Med Chem; 2008 Oct; 51(20):6381-92. PubMed ID: 18821749
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The interactions of phenanthroline compounds with DNAs: preferential binding to telomeric quadruplex over duplex.
    Wang L; Wu Y; Chen T; Wei C
    Int J Biol Macromol; 2013 Jan; 52():1-8. PubMed ID: 22940238
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tri- and tetra-substituted naphthalene diimides as potent G-quadruplex ligands.
    Cuenca F; Greciano O; Gunaratnam M; Haider S; Munnur D; Nanjunda R; Wilson WD; Neidle S
    Bioorg Med Chem Lett; 2008 Mar; 18(5):1668-73. PubMed ID: 18243701
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Isaindigotone derivatives: a new class of highly selective ligands for telomeric G-quadruplex DNA.
    Tan JH; Ou TM; Hou JQ; Lu YJ; Huang SL; Luo HB; Wu JY; Huang ZS; Wong KY; Gu LQ
    J Med Chem; 2009 May; 52(9):2825-35. PubMed ID: 19354252
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Selective G-quadruplex ligands: the significant role of side chain charge density in a series of perylene derivatives.
    Micheli E; Lombardo CM; D'Ambrosio D; Franceschin M; Neidle S; Savino M
    Bioorg Med Chem Lett; 2009 Jul; 19(14):3903-8. PubMed ID: 19376705
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Affinity and selectivity of G4 ligands measured by FRET.
    De Cian A; Guittat L; Shin-ya K; Riou JF; Mergny JL
    Nucleic Acids Symp Ser (Oxf); 2005; (49):235-6. PubMed ID: 17150720
    [TBL] [Abstract][Full Text] [Related]  

  • 20. G-quadruplex stabilizer 3,6-bis(1-methyl-4-vinylpyridinium)carbazole diiodide induces accelerated senescence and inhibits tumorigenic properties in cancer cells.
    Huang FC; Chang CC; Lou PJ; Kuo IC; Chien CW; Chen CT; Shieh FY; Chang TC; Lin JJ
    Mol Cancer Res; 2008 Jun; 6(6):955-64. PubMed ID: 18515756
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.