BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

218 related articles for article (PubMed ID: 21349849)

  • 1. Mutant HFE H63D protein is associated with prolonged endoplasmic reticulum stress and increased neuronal vulnerability.
    Liu Y; Lee SY; Neely E; Nandar W; Moyo M; Simmons Z; Connor JR
    J Biol Chem; 2011 Apr; 286(15):13161-70. PubMed ID: 21349849
    [TBL] [Abstract][Full Text] [Related]  

  • 2. H63D HFE genotype accelerates disease progression in animal models of amyotrophic lateral sclerosis.
    Nandar W; Neely EB; Simmons Z; Connor JR
    Biochim Biophys Acta; 2014 Dec; 1842(12 Pt A):2413-26. PubMed ID: 25283820
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A mutation in the HFE gene is associated with altered brain iron profiles and increased oxidative stress in mice.
    Nandar W; Neely EB; Unger E; Connor JR
    Biochim Biophys Acta; 2013 Jun; 1832(6):729-41. PubMed ID: 23429074
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Prolyl-peptidyl isomerase, Pin1, phosphorylation is compromised in association with the expression of the HFE polymorphic allele, H63D.
    Hall EC; Lee SY; Simmons Z; Neely EB; Nandar W; Connor JR
    Biochim Biophys Acta; 2010 Apr; 1802(4):389-95. PubMed ID: 20060900
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The H63D HFE gene variant promotes activation of the intrinsic apoptotic pathway via mitochondria dysfunction following β-amyloid peptide exposure.
    Mairuae N; Hall Ii EC; Cheepsunthorn P; Lee SY; Connor JR
    J Neurosci Res; 2010 Nov; 88(14):3079-89. PubMed ID: 20734416
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Contribution of the H63D mutation in HFE to murine hereditary hemochromatosis.
    Tomatsu S; Orii KO; Fleming RE; Holden CC; Waheed A; Britton RS; Gutierrez MA; Velez-Castrillon S; Bacon BR; Sly WS
    Proc Natl Acad Sci U S A; 2003 Dec; 100(26):15788-93. PubMed ID: 14673107
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The effects of okra (Abelmoschus esculentus Linn.) on the cellular events associated with Alzheimer's disease in a stably expressed HFE neuroblastoma SH-SY5Y cell line.
    Mairuae N; Connor JR; Lee SY; Cheepsunthorn P; Tongjaroenbuangam W
    Neurosci Lett; 2015 Aug; 603():6-11. PubMed ID: 26170247
    [TBL] [Abstract][Full Text] [Related]  

  • 8. H63D mutation in hemochromatosis alters cholesterol metabolism and induces memory impairment.
    Ali-Rahmani F; Grigson PS; Lee S; Neely E; Connor JR; Schengrund CL
    Neurobiol Aging; 2014 Jun; 35(6):1511.e1-12. PubMed ID: 24439478
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Influence of HFE variants and cellular iron on monocyte chemoattractant protein-1.
    Mitchell RM; Lee SY; Randazzo WT; Simmons Z; Connor JR
    J Neuroinflammation; 2009 Feb; 6():6. PubMed ID: 19228389
    [TBL] [Abstract][Full Text] [Related]  

  • 10. HFE gene variants affect iron in the brain.
    Nandar W; Connor JR
    J Nutr; 2011 Apr; 141(4):729S-739S. PubMed ID: 21346098
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Consequences of expressing mutants of the hemochromatosis gene (HFE) into a human neuronal cell line lacking endogenous HFE.
    Lee SY; Patton SM; Henderson RJ; Connor JR
    FASEB J; 2007 Feb; 21(2):564-76. PubMed ID: 17194693
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Expression of hereditary hemochromatosis C282Y HFE protein in HEK293 cells activates specific endoplasmic reticulum stress responses.
    Lawless MW; Mankan AK; White M; O'Dwyer MJ; Norris S
    BMC Cell Biol; 2007 Jul; 8():30. PubMed ID: 17650303
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Expression of the HFE allelic variant H63D in SH-SY5Y cells affects tau phosphorylation at serine residues.
    Hall EC; Lee SY; Mairuae N; Simmons Z; Connor JR
    Neurobiol Aging; 2011 Aug; 32(8):1409-19. PubMed ID: 19775775
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Overexpression of HFE in HepG2 cells reveals differences in intracellular distribution and co-localization of wt- and mutated forms.
    Pinto JP; Ramos P; de Sousa M
    Blood Cells Mol Dis; 2007; 39(1):75-81. PubMed ID: 17428702
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Increased incidence of the Hfe mutation in amyotrophic lateral sclerosis and related cellular consequences.
    Wang XS; Lee S; Simmons Z; Boyer P; Scott K; Liu W; Connor J
    J Neurol Sci; 2004 Dec; 227(1):27-33. PubMed ID: 15546588
    [TBL] [Abstract][Full Text] [Related]  

  • 16. H63D HFE polymorphisms are associated with increased disease duration and decreased muscle superoxide dismutase-1 expression in amyotrophic lateral sclerosis patients.
    Su XW; Lee SY; Mitchell RM; Stephens HE; Simmons Z; Connor JR
    Muscle Nerve; 2013 Aug; 48(2):242-6. PubMed ID: 23813494
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Reduced white matter MRI transverse relaxation rate in cognitively normal H63D-HFE human carriers and H67D-HFE mice.
    Meadowcroft MD; Wang J; Purnell CJ; Peters DG; Eslinger PJ; Neely EB; Gill DJ; Vasavada M; Ali-Rahmani F; Yang QX; Connor JR
    Brain Imaging Behav; 2016 Dec; 10(4):1231-1242. PubMed ID: 26660104
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Contribution of different HFE genotypes to iron overload disease: a pooled analysis.
    Burke W; Imperatore G; McDonnell SM; Baron RC; Khoury MJ
    Genet Med; 2000; 2(5):271-7. PubMed ID: 11399207
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Major histocompatibility complex class I associations in iron overload: evidence for a new link between the HFE H63D mutation, HLA-A29, and non-classical forms of hemochromatosis.
    Porto G; Alves H; Rodrigues P; Cabeda JM; Portal C; Ruivo A; Justiça B; Wolff R; De Sousa M
    Immunogenetics; 1998 Apr; 47(5):404-10. PubMed ID: 9510559
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The association between H63D mutations in HFE and amyotrophic lateral sclerosis in a Dutch population.
    Sutedja NA; Sinke RJ; Van Vught PW; Van der Linden MW; Wokke JH; Van Duijn CM; Njajou OT; Van der Schouw YT; Veldink JH; Van den Berg LH
    Arch Neurol; 2007 Jan; 64(1):63-7. PubMed ID: 17210810
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.