241 related articles for article (PubMed ID: 21353571)
1. Structure based design and syntheses of amino-1H-pyrazole amide derivatives as selective Raf kinase inhibitors in melanoma cells.
Kim MH; Kim M; Yu H; Kim H; Yoo KH; Sim T; Hah JM
Bioorg Med Chem; 2011 Mar; 19(6):1915-23. PubMed ID: 21353571
[TBL] [Abstract][Full Text] [Related]
2. Syntheses of phenylpyrazolodiazepin-7-ones as conformationally rigid analogs of aminopyrazole amide scaffold and their antiproliferative effects on cancer cells.
Kim H; Kim M; Lee J; Yu H; Hah JM
Bioorg Med Chem; 2011 Nov; 19(22):6760-7. PubMed ID: 22014755
[TBL] [Abstract][Full Text] [Related]
3. Discovery and initial SAR of pyrimidin-4-yl-1H-imidazole derivatives with antiproliferative activity against melanoma cell lines.
Lee J; Kim H; Yu H; Chung JY; Oh CH; Yoo KH; Sim T; Hah JM
Bioorg Med Chem Lett; 2010 Mar; 20(5):1573-7. PubMed ID: 20149658
[TBL] [Abstract][Full Text] [Related]
4. 1,4-dihydropyrazolo[4,3-d]imidazole phenyl derivatives: a novel type II Raf kinase inhibitors.
Yu H; Jung Y; Kim H; Lee J; Oh CH; Yoo KH; Sim T; Hah JM
Bioorg Med Chem Lett; 2010 Jun; 20(12):3805-8. PubMed ID: 20466542
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis and antitumor activities of novel bis-aryl ureas derivatives as Raf kinase inhibitors.
Zhan W; Li Y; Huang W; Zhao Y; Yao Z; Yu S; Yuan S; Jiang F; Yao S; Li S
Bioorg Med Chem; 2012 Jul; 20(14):4323-9. PubMed ID: 22721924
[TBL] [Abstract][Full Text] [Related]
6. Synthesis, biological evaluation of novel 4,5-dihydro-2H-pyrazole 2-hydroxyphenyl derivatives as BRAF inhibitors.
Liu JJ; Zhang H; Sun J; Wang ZC; Yang YS; Li DD; Zhang F; Gong HB; Zhu HL
Bioorg Med Chem; 2012 Oct; 20(20):6089-96. PubMed ID: 22985957
[TBL] [Abstract][Full Text] [Related]
7. Design, synthesis, and antiproliferative activity of 3,4-diarylpyrazole-1-carboxamide derivatives against melanoma cell line.
El-Gamal MI; Choi HS; Cho HG; Hong JH; Yoo KH; Oh CH
Arch Pharm (Weinheim); 2011 Nov; 344(11):745-54. PubMed ID: 21954060
[TBL] [Abstract][Full Text] [Related]
8. New diarylureas and diarylamides containing 1,3,4-triarylpyrazole scaffold: Synthesis, antiproliferative evaluation against melanoma cell lines, ERK kinase inhibition, and molecular docking studies.
Choi WK; El-Gamal MI; Choi HS; Baek D; Oh CH
Eur J Med Chem; 2011 Dec; 46(12):5754-62. PubMed ID: 22014559
[TBL] [Abstract][Full Text] [Related]
9. Design, modification and 3D QSAR studies of novel 2,3-dihydrobenzo[b][1,4]dioxin-containing 4,5-dihydro-1H-pyrazole derivatives as inhibitors of B-Raf kinase.
Yang YS; Li QS; Sun S; Zhang YB; Wang XL; Zhang F; Tang JF; Zhu HL
Bioorg Med Chem; 2012 Oct; 20(20):6048-58. PubMed ID: 22985962
[TBL] [Abstract][Full Text] [Related]
10. Synthesis of 1H-pyrazole-1-carboxamide derivatives and their antiproliferative activity against melanoma cell line.
El-Gamal MI; Sim TB; Hong JH; Cho JH; Yoo KH; Oh CH
Arch Pharm (Weinheim); 2011 Mar; 344(3):197-204. PubMed ID: 21384419
[TBL] [Abstract][Full Text] [Related]
11. Synthesis, biological evaluation, and molecular docking studies of 1,3,4-thiadiazol-2-amide derivatives as novel anticancer agents.
Yang XH; Xiang L; Li X; Zhao TT; Zhang H; Zhou WP; Wang XM; Gong HB; Zhu HL
Bioorg Med Chem; 2012 May; 20(9):2789-95. PubMed ID: 22503364
[TBL] [Abstract][Full Text] [Related]
12. Tri- and tetrasubstituted pyrazole derivates: regioisomerism switches activity from p38MAP kinase to important cancer kinases.
Abu Thaher B; Arnsmann M; Totzke F; Ehlert JE; Kubbutat MH; Schächtele C; Zimmermann MO; Koch P; Boeckler FM; Laufer SA
J Med Chem; 2012 Jan; 55(2):961-5. PubMed ID: 22185282
[TBL] [Abstract][Full Text] [Related]
13. Synthesis, biological evaluation, and molecular docking studies of N,1,3-triphenyl-1H-pyrazole-4-carboxamide derivatives as anticancer agents.
Li X; Lu X; Xing M; Yang XH; Zhao TT; Gong HB; Zhu HL
Bioorg Med Chem Lett; 2012 Jun; 22(11):3589-93. PubMed ID: 22572580
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and antiproliferative activity of pyrrolo[3,2-b]pyridine derivatives against melanoma.
Kim HJ; Jung MH; Kim H; El-Gamal MI; Sim TB; Lee SH; Hong JH; Hah JM; Cho JH; Choi JH; Yoo KH; Oh CH
Bioorg Med Chem Lett; 2010 Jan; 20(1):413-7. PubMed ID: 19897366
[TBL] [Abstract][Full Text] [Related]
15. Identification of novel 3,5-diarylpyrazoline derivatives containing salicylamide moiety as potential anti-melanoma agents.
Li QS; Lv XH; Zhang YB; Dong JJ; Zhou WP; Yang Y; Zhu HL
Bioorg Med Chem Lett; 2012 Nov; 22(21):6596-601. PubMed ID: 23025996
[TBL] [Abstract][Full Text] [Related]
16. Design, synthesis and biological evaluation of novel 5-phenyl-1H-pyrazole derivatives as potential BRAF(V600E) inhibitors.
Wang SF; Zhu YL; Zhu PT; Makawana JA; Zhang YL; Zhao MY; Lv PC; Zhu HL
Bioorg Med Chem; 2014 Nov; 22(21):6201-8. PubMed ID: 25267006
[TBL] [Abstract][Full Text] [Related]
17. Discovery and optimization of pyrazoline compounds as B-Raf inhibitors.
Duffey MO; Adams R; Blackburn C; Chau RW; Chen S; Galvin KM; Garcia K; Gould AE; Greenspan PD; Harrison S; Huang SC; Kim MS; Kulkarni B; Langston S; Liu JX; Ma LT; Menon S; Nagayoshi M; Rowland RS; Vos TJ; Xu T; Yang JJ; Yu S; Zhang Q
Bioorg Med Chem Lett; 2010 Aug; 20(16):4800-4. PubMed ID: 20634068
[TBL] [Abstract][Full Text] [Related]
18. Design, synthesis and biological evaluation of benzyl 2-(1H-imidazole-1-yl) pyrimidine analogues as selective and potent Raf inhibitors.
Kim M; Lee J; Jung K; Kim H; Aman W; Ryu JS; Hah JM
Bioorg Med Chem Lett; 2014 Aug; 24(15):3600-4. PubMed ID: 24878193
[TBL] [Abstract][Full Text] [Related]
19. Design and synthesis of N-(4-aminopyridin-2-yl)amides as B-Raf(V600E) inhibitors.
Li X; Shen J; Tan L; Zhang Z; Gao D; Luo J; Cheng H; Zhou X; Ma J; Ding K; Lu X
Bioorg Med Chem Lett; 2016 Jun; 26(12):2760-2763. PubMed ID: 27155899
[TBL] [Abstract][Full Text] [Related]
20. Design and synthesis of isoquinolines and benzimidazoles as RAF kinase inhibitors.
Buchstaller HP; Burgdorf L; Finsinger D; Stieber F; Sirrenberg C; Amendt C; Grell M; Zenke F; Krier M
Bioorg Med Chem Lett; 2011 Apr; 21(8):2264-9. PubMed ID: 21420298
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]