BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

285 related articles for article (PubMed ID: 21357822)

  • 1. Cardiac raptor ablation impairs adaptive hypertrophy, alters metabolic gene expression, and causes heart failure in mice.
    Shende P; Plaisance I; Morandi C; Pellieux C; Berthonneche C; Zorzato F; Krishnan J; Lerch R; Hall MN; Rüegg MA; Pedrazzini T; Brink M
    Circulation; 2011 Mar; 123(10):1073-82. PubMed ID: 21357822
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activation or inactivation of cardiac Akt/mTOR signaling diverges physiological from pathological hypertrophy.
    Kemi OJ; Ceci M; Wisloff U; Grimaldi S; Gallo P; Smith GL; Condorelli G; Ellingsen O
    J Cell Physiol; 2008 Feb; 214(2):316-21. PubMed ID: 17941081
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cardiac mTOR complex 2 preserves ventricular function in pressure-overload hypertrophy.
    Shende P; Xu L; Morandi C; Pentassuglia L; Heim P; Lebboukh S; Berthonneche C; Pedrazzini T; Kaufmann BA; Hall MN; Rüegg MA; Brink M
    Cardiovasc Res; 2016 Jan; 109(1):103-14. PubMed ID: 26598511
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The alteration of protein prenylation induces cardiomyocyte hypertrophy through Rheb-mTORC1 signalling and leads to chronic heart failure.
    Xu N; Guan S; Chen Z; Yu Y; Xie J; Pan FY; Zhao NW; Liu L; Yang ZZ; Gao X; Xu B; Li CJ
    J Pathol; 2015 Apr; 235(5):672-85. PubMed ID: 25385233
    [TBL] [Abstract][Full Text] [Related]  

  • 5. mTOR Hyperactivation by Ablation of Tuberous Sclerosis Complex 2 in the Mouse Heart Induces Cardiac Dysfunction with the Increased Number of Small Mitochondria Mediated through the Down-Regulation of Autophagy.
    Taneike M; Nishida K; Omiya S; Zarrinpashneh E; Misaka T; Kitazume-Taneike R; Austin R; Takaoka M; Yamaguchi O; Gambello MJ; Shah AM; Otsu K
    PLoS One; 2016; 11(3):e0152628. PubMed ID: 27023784
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice.
    Zhang D; Contu R; Latronico MV; Zhang J; Rizzi R; Catalucci D; Miyamoto S; Huang K; Ceci M; Gu Y; Dalton ND; Peterson KL; Guan KL; Brown JH; Chen J; Sonenberg N; Condorelli G
    J Clin Invest; 2010 Aug; 120(8):2805-16. PubMed ID: 20644257
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Loss of NOX2 (gp91phox) prevents oxidative stress and progression to advanced heart failure.
    Parajuli N; Patel VB; Wang W; Basu R; Oudit GY
    Clin Sci (Lond); 2014 Sep; 127(5):331-40. PubMed ID: 24624929
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of mTOR reduces chronic pressure-overload cardiac hypertrophy and fibrosis.
    Gao XM; Wong G; Wang B; Kiriazis H; Moore XL; Su YD; Dart A; Du XJ
    J Hypertens; 2006 Aug; 24(8):1663-70. PubMed ID: 16877971
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Raptor-rictor axis in TGFbeta-induced protein synthesis.
    Das F; Ghosh-Choudhury N; Mahimainathan L; Venkatesan B; Feliers D; Riley DJ; Kasinath BS; Choudhury GG
    Cell Signal; 2008 Feb; 20(2):409-23. PubMed ID: 18068336
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Specific and sustained down-regulation of genes involved in fatty acid metabolism is not a hallmark of progression to cardiac failure in mice.
    de Brouwer KF; Degens H; Aartsen WM; Lindhout M; Bitsch NJ; Gilde AJ; Willemsen PH; Janssen BJ; van der Vusse GJ; van Bilsen M
    J Mol Cell Cardiol; 2006 Jun; 40(6):838-45. PubMed ID: 16697005
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Downregulation of survival signalling pathways and increased apoptosis in the transition of pressure overload-induced cardiac hypertrophy to heart failure.
    Li XM; Ma YT; Yang YN; Liu F; Chen BD; Han W; Zhang JF; Gao XM
    Clin Exp Pharmacol Physiol; 2009 Nov; 36(11):1054-61. PubMed ID: 19566828
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Leucine induces myofibrillar protein accretion in cultured skeletal muscle through mTOR dependent and -independent control of myosin heavy chain mRNA levels.
    Haegens A; Schols AM; van Essen AL; van Loon LJ; Langen RC
    Mol Nutr Food Res; 2012 May; 56(5):741-52. PubMed ID: 22648621
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cardiac steroidogenesis and glucocorticoid in the development of cardiac hypertrophy during the progression to heart failure.
    Ohtani T; Mano T; Hikoso S; Sakata Y; Nishio M; Takeda Y; Otsu K; Miwa T; Masuyama T; Hori M; Yamamoto K
    J Hypertens; 2009 May; 27(5):1074-83. PubMed ID: 19349910
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Post-infarction heart failure in the rat is associated with distinct alterations in cardiac myocyte molecular phenotype.
    Yue P; Long CS; Austin R; Chang KC; Simpson PC; Massie BM
    J Mol Cell Cardiol; 1998 Aug; 30(8):1615-30. PubMed ID: 9737947
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Prolonged endoplasmic reticulum stress in hypertrophic and failing heart after aortic constriction: possible contribution of endoplasmic reticulum stress to cardiac myocyte apoptosis.
    Okada K; Minamino T; Tsukamoto Y; Liao Y; Tsukamoto O; Takashima S; Hirata A; Fujita M; Nagamachi Y; Nakatani T; Yutani C; Ozawa K; Ogawa S; Tomoike H; Hori M; Kitakaze M
    Circulation; 2004 Aug; 110(6):705-12. PubMed ID: 15289376
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Celiprolol, a vasodilatory beta-blocker, inhibits pressure overload-induced cardiac hypertrophy and prevents the transition to heart failure via nitric oxide-dependent mechanisms in mice.
    Liao Y; Asakura M; Takashima S; Ogai A; Asano Y; Shintani Y; Minamino T; Asanuma H; Sanada S; Kim J; Kitamura S; Tomoike H; Hori M; Kitakaze M
    Circulation; 2004 Aug; 110(6):692-9. PubMed ID: 15262839
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cardiomyocyte-specific loss of mitochondrial p32/C1qbp causes cardiomyopathy and activates stress responses.
    Saito T; Uchiumi T; Yagi M; Amamoto R; Setoyama D; Matsushima Y; Kang D
    Cardiovasc Res; 2017 Aug; 113(10):1173-1185. PubMed ID: 28498888
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of mTOR signaling with rapamycin regresses established cardiac hypertrophy induced by pressure overload.
    McMullen JR; Sherwood MC; Tarnavski O; Zhang L; Dorfman AL; Shioi T; Izumo S
    Circulation; 2004 Jun; 109(24):3050-5. PubMed ID: 15184287
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The rapid activation of protein synthesis by growth hormone requires signaling through mTOR.
    Hayashi AA; Proud CG
    Am J Physiol Endocrinol Metab; 2007 Jun; 292(6):E1647-55. PubMed ID: 17284572
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Acute heart failure with cardiomyocyte atrophy induced in adult mice by ablation of cardiac myosin light chain kinase.
    Massengill MT; Ashraf HM; Chowdhury RR; Chrzanowski SM; Kar J; Warren SA; Walter GA; Zeng H; Kang BH; Anderson RH; Moss RL; Kasahara H
    Cardiovasc Res; 2016 Jul; 111(1):34-43. PubMed ID: 27025239
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.