207 related articles for article (PubMed ID: 21358804)
1. K-Ras mediated murine epidermal tumorigenesis is dependent upon and associated with elevated Rac1 activity.
Samuel MS; Lourenço FC; Olson MF
PLoS One; 2011 Feb; 6(2):e17143. PubMed ID: 21358804
[TBL] [Abstract][Full Text] [Related]
2. Requirement for Rac1 in a K-ras induced lung cancer in the mouse.
Kissil JL; Walmsley MJ; Hanlon L; Haigis KM; Bender Kim CF; Sweet-Cordero A; Eckman MS; Tuveson DA; Capobianco AJ; Tybulewicz VL; Jacks T
Cancer Res; 2007 Sep; 67(17):8089-94. PubMed ID: 17804720
[TBL] [Abstract][Full Text] [Related]
3. The Rac1 splice form Rac1b promotes K-ras-induced lung tumorigenesis.
Zhou C; Licciulli S; Avila JL; Cho M; Troutman S; Jiang P; Kossenkov AV; Showe LC; Liu Q; Vachani A; Albelda SM; Kissil JL
Oncogene; 2013 Feb; 32(7):903-9. PubMed ID: 22430205
[TBL] [Abstract][Full Text] [Related]
4. A critical role for ras-mediated, epidermal growth factor receptor-dependent angiogenesis in mouse skin carcinogenesis.
Casanova ML; Larcher F; Casanova B; Murillas R; Fernández-Aceñero MJ; Villanueva C; Martínez-Palacio J; Ullrich A; Conti CJ; Jorcano JL
Cancer Res; 2002 Jun; 62(12):3402-7. PubMed ID: 12067982
[TBL] [Abstract][Full Text] [Related]
5. The survival kinase Mirk/Dyrk1B is a downstream effector of oncogenic K-ras in pancreatic cancer.
Jin K; Park S; Ewton DZ; Friedman E
Cancer Res; 2007 Aug; 67(15):7247-55. PubMed ID: 17671193
[TBL] [Abstract][Full Text] [Related]
6. Deficiency of kinase suppressor of Ras1 prevents oncogenic ras signaling in mice.
Lozano J; Xing R; Cai Z; Jensen HL; Trempus C; Mark W; Cannon R; Kolesnick R
Cancer Res; 2003 Jul; 63(14):4232-8. PubMed ID: 12874031
[TBL] [Abstract][Full Text] [Related]
7. Alterations in epidermal biochemistry as a consequence of stage-specific genetic changes in skin carcinogenesis.
Yuspa SH; Kilkenny A; Cheng C; Roop D; Hennings H; Kruszewski F; Lee E; Strickland J; Greenhalgh DA
Environ Health Perspect; 1991 Jun; 93():3-10. PubMed ID: 1773799
[TBL] [Abstract][Full Text] [Related]
8. Constitutive expression of erbB2 in epidermis of transgenic mice results in epidermal hyperproliferation and spontaneous skin tumor development.
Kiguchi K; Bol D; Carbajal S; Beltrán L; Moats S; Chan K; Jorcano J; DiGiovanni J
Oncogene; 2000 Aug; 19(37):4243-54. PubMed ID: 10980598
[TBL] [Abstract][Full Text] [Related]
9. Conditional expression of K-ras in an epithelial compartment that includes the stem cells is sufficient to promote squamous cell carcinogenesis.
Vitale-Cross L; Amornphimoltham P; Fisher G; Molinolo AA; Gutkind JS
Cancer Res; 2004 Dec; 64(24):8804-7. PubMed ID: 15604235
[TBL] [Abstract][Full Text] [Related]
10. Mouse tissues that undergo neoplastic progression after K-Ras activation are distinguished by nuclear translocation of phospho-Erk1/2 and robust tumor suppressor responses.
Parikh N; Shuck RL; Nguyen TA; Herron A; Donehower LA
Mol Cancer Res; 2012 Jun; 10(6):845-55. PubMed ID: 22532587
[TBL] [Abstract][Full Text] [Related]
11. Rac1 is crucial for Ras-dependent skin tumor formation by controlling Pak1-Mek-Erk hyperactivation and hyperproliferation in vivo.
Wang Z; Pedersen E; Basse A; Lefever T; Peyrollier K; Kapoor S; Mei Q; Karlsson R; Chrostek-Grashoff A; Brakebusch C
Oncogene; 2010 Jun; 29(23):3362-73. PubMed ID: 20383193
[TBL] [Abstract][Full Text] [Related]
12. Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation.
Khosravi-Far R; Solski PA; Clark GJ; Kinch MS; Der CJ
Mol Cell Biol; 1995 Nov; 15(11):6443-53. PubMed ID: 7565796
[TBL] [Abstract][Full Text] [Related]
13. Acute sensitivity of the oral mucosa to oncogenic K-ras.
van der Weyden L; Alcolea MP; Jones PH; Rust AG; Arends MJ; Adams DJ
J Pathol; 2011 May; 224(1):22-32. PubMed ID: 21381032
[TBL] [Abstract][Full Text] [Related]
14. Activated mutant NRas(Q61K) drives aberrant melanocyte signaling, survival, and invasiveness via a Rac1-dependent mechanism.
Li A; Ma Y; Jin M; Mason S; Mort RL; Blyth K; Larue L; Sansom OJ; Machesky LM
J Invest Dermatol; 2012 Nov; 132(11):2610-21. PubMed ID: 22718121
[TBL] [Abstract][Full Text] [Related]
15. The P34G mutation reduces the transforming activity of K-Ras and N-Ras in NIH 3T3 cells but not of H-Ras.
Oliva JL; Zarich N; Martínez N; Jorge R; Castrillo A; Azañedo M; García-Vargas S; Gutiérrez-Eisman S; Juarranz A; Boscá L; Gutkind JS; Rojas JM
J Biol Chem; 2004 Aug; 279(32):33480-91. PubMed ID: 15181015
[TBL] [Abstract][Full Text] [Related]
16. Dose-dependent mutation profile in the c-Ha-ras proto-oncogene of skin tumors in mice initiated with benzo[a]pyrene.
Wei SJ; Chang RL; Merkler KA; Gwynne M; Cui XX; Murthy B; Huang MT; Xie JG; Lu YP; Lou YR; Jerina DM; Conney AH
Carcinogenesis; 1999 Sep; 20(9):1689-96. PubMed ID: 10469612
[TBL] [Abstract][Full Text] [Related]
17. Rac1 function is required for Src-induced transformation. Evidence of a role for Tiam1 and Vav2 in Rac activation by Src.
Servitja JM; Marinissen MJ; Sodhi A; Bustelo XR; Gutkind JS
J Biol Chem; 2003 Sep; 278(36):34339-46. PubMed ID: 12810717
[TBL] [Abstract][Full Text] [Related]
18. Oncogenic K-Ras down-regulates Rac1 and RhoA activity and enhances migration and invasion of pancreatic carcinoma cells through activation of p38.
Dreissigacker U; Mueller MS; Unger M; Siegert P; Genze F; Gierschik P; Giehl K
Cell Signal; 2006 Aug; 18(8):1156-68. PubMed ID: 16257181
[TBL] [Abstract][Full Text] [Related]
19. H-Ras-specific activation of Rac-MKK3/6-p38 pathway: its critical role in invasion and migration of breast epithelial cells.
Shin I; Kim S; Song H; Kim HR; Moon A
J Biol Chem; 2005 Apr; 280(15):14675-83. PubMed ID: 15677464
[TBL] [Abstract][Full Text] [Related]
20. Cooperation of Ha-ras and Bcl-2 during multistep skin carcinogenesis.
Lee S; Chari NS; Kim HW; Wang X; Roop DR; Cho SH; DiGiovanni J; McDonnell TJ
Mol Carcinog; 2007 Dec; 46(12):949-57. PubMed ID: 17538944
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
