These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

137 related articles for article (PubMed ID: 21360595)

  • 1. Inhibition of 3,4-methylenedioxymethamphetamine metabolism leads to marked decrease in 3,4-dihydroxymethamphetamine formation but no change in serotonin neurotoxicity: implications for mechanisms of neurotoxicity.
    Mueller M; Yuan J; Maldonado Adrian C; McCann UD; Ricaurte GA
    Synapse; 2011 Oct; 65(10):983-90. PubMed ID: 21360595
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Further studies on the role of metabolites in (+/-)-3,4-methylenedioxymethamphetamine-induced serotonergic neurotoxicity.
    Mueller M; Yuan J; Felim A; Neudörffer A; Peters FT; Maurer HH; McCann UD; Largeron M; Ricaurte GA
    Drug Metab Dispos; 2009 Oct; 37(10):2079-86. PubMed ID: 19628751
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Glutathione and N-acetylcysteine conjugates of alpha-methyldopamine produce serotonergic neurotoxicity: possible role in methylenedioxyamphetamine-mediated neurotoxicity.
    Bai F; Lau SS; Monks TJ
    Chem Res Toxicol; 1999 Dec; 12(12):1150-7. PubMed ID: 10604863
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Accumulation of neurotoxic thioether metabolites of 3,4-(+/-)-methylenedioxymethamphetamine in rat brain.
    Erives GV; Lau SS; Monks TJ
    J Pharmacol Exp Ther; 2008 Jan; 324(1):284-91. PubMed ID: 17906065
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and in vitro cytotoxicity profile of the R-enantiomer of 3,4-dihydroxymethamphetamine (R-(-)-HHMA): comparison with related catecholamines.
    Felim A; Herrera G; Neudörffer A; Blanco M; O'Connor JE; Largeron M
    Chem Res Toxicol; 2010 Jan; 23(1):211-9. PubMed ID: 20017534
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 3,4-Dihydroxymethamphetamine (HHMA). A major in vivo 3,4-methylenedioxymethamphetamine (MDMA) metabolite in humans.
    Segura M; Ortuño J; Farré M; McLure JA; Pujadas M; Pizarro N; Llebaria A; Joglar J; Roset PN; Segura J; de La Torre R
    Chem Res Toxicol; 2001 Sep; 14(9):1203-8. PubMed ID: 11559034
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and neurotoxicity profile of 2,4,5-trihydroxymethamphetamine and its 6-(N-acetylcystein-S-yl) conjugate.
    Neudörffer A; Mueller M; Martinez CM; Mechan A; McCann U; Ricaurte GA; Largeron M
    Chem Res Toxicol; 2011 Jun; 24(6):968-78. PubMed ID: 21557581
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effects of MDMA (ecstasy) and two of its metabolites on rat embryos in vitro.
    Barenys M; Flick B; Boix N; Almeida B; Joglar J; Klug S; Llobet JM
    Reprod Toxicol; 2012 Aug; 34(1):57-65. PubMed ID: 22391229
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Comparative neurochemical profile of 3,4-methylenedioxymethamphetamine and its metabolite alpha-methyldopamine on key targets of MDMA neurotoxicity.
    Escubedo E; Abad S; Torres I; Camarasa J; Pubill D
    Neurochem Int; 2011 Jan; 58(1):92-101. PubMed ID: 21074589
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 2,5-Bis-(glutathion-S-yl)-alpha-methyldopamine, a putative metabolite of (+/-)-3,4-methylenedioxyamphetamine, decreases brain serotonin concentrations.
    Miller RT; Lau SS; Monks TJ
    Eur J Pharmacol; 1997 Apr; 323(2-3):173-80. PubMed ID: 9128836
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A convenient biomimetic synthesis of optically active putative neurotoxic metabolites of MDMA ("ecstasy") from R-(-)- and S-(+)-N-methyl-α-methyldopamine precursors.
    Martinez CM; Neudörffer A; Largeron M
    Org Biomol Chem; 2012 May; 10(18):3739-48. PubMed ID: 22456797
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Serotonergic neurotoxic thioether metabolites of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy"): synthesis, isolation, and characterization of diastereoisomers.
    Pizarro N; de la Torre R; Joglar J; Okumura N; Perfetti X; Lau SS; Monks TJ
    Chem Res Toxicol; 2008 Dec; 21(12):2272-9. PubMed ID: 19548351
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A comparative study on the acute and long-term effects of MDMA and 3,4-dihydroxymethamphetamine (HHMA) on brain monoamine levels after i.p. or striatal administration in mice.
    Escobedo I; O'Shea E; Orio L; Sanchez V; Segura M; de la Torre R; Farre M; Green AR; Colado MI
    Br J Pharmacol; 2005 Jan; 144(2):231-41. PubMed ID: 15665862
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effects of 3,4-methylenedioxymethamphetamine (MDMA) and its main metabolites on cardiovascular function in conscious rats.
    Schindler CW; Thorndike EB; Blough BE; Tella SR; Goldberg SR; Baumann MH
    Br J Pharmacol; 2014 Jan; 171(1):83-91. PubMed ID: 24328722
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Neurotoxic thioether adducts of 3,4-methylenedioxymethamphetamine identified in human urine after ecstasy ingestion.
    Perfetti X; O'Mathúna B; Pizarro N; Cuyàs E; Khymenets O; Almeida B; Pellegrini M; Pichini S; Lau SS; Monks TJ; Farré M; Pascual JA; Joglar J; de la Torre R
    Drug Metab Dispos; 2009 Jul; 37(7):1448-55. PubMed ID: 19349378
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The relationship between core body temperature and 3,4-methylenedioxymethamphetamine metabolism in rats: implications for neurotoxicity.
    Goni-Allo B; O Mathúna B; Segura M; Puerta E; Lasheras B; de la Torre R; Aguirre N
    Psychopharmacology (Berl); 2008 Apr; 197(2):263-78. PubMed ID: 18074122
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Assessment of the role of alpha-methylepinine in the neurotoxicity of MDMA.
    Steele TD; Brewster WK; Johnson MP; Nichols DE; Yim GK
    Pharmacol Biochem Behav; 1991 Feb; 38(2):345-51. PubMed ID: 1676172
    [TBL] [Abstract][Full Text] [Related]  

  • 18. On the role of tyrosine and peripheral metabolism in 3,4-methylenedioxymethamphetamine-induced serotonin neurotoxicity in rats.
    Goñi-Allo B; Puerta E; Mathúna BO; Hervias I; Lasheras B; de la Torre R; Aguirre N
    Neuropharmacology; 2008 Apr; 54(5):885-900. PubMed ID: 18329670
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Glial cell response to 3,4-(+/-)-methylenedioxymethamphetamine and its metabolites.
    Herndon JM; Cholanians AB; Lau SS; Monks TJ
    Toxicol Sci; 2014 Mar; 138(1):130-8. PubMed ID: 24299738
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The neurotoxic effects of methylenedioxymethamphetamine (MDMA) and its metabolites on rat brain spheroids in culture.
    Walker TM; Davenport-Jones JE; Fox RM; Atterwill CK
    Cell Biol Toxicol; 1999 Jun; 15(3):137-42. PubMed ID: 10580546
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.