BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

198 related articles for article (PubMed ID: 21362629)

  • 1. Activation of nuclear TR3 (NR4A1) by a diindolylmethane analog induces apoptosis and proapoptotic genes in pancreatic cancer cells and tumors.
    Yoon K; Lee SO; Cho SD; Kim K; Khan S; Safe S
    Carcinogenesis; 2011 Jun; 32(6):836-42. PubMed ID: 21362629
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activation of nerve growth factor-induced B alpha by methylene-substituted diindolylmethanes in bladder cancer cells induces apoptosis and inhibits tumor growth.
    Cho SD; Lee SO; Chintharlapalli S; Abdelrahim M; Khan S; Yoon K; Kamat AM; Safe S
    Mol Pharmacol; 2010 Mar; 77(3):396-404. PubMed ID: 20023005
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inactivation of the orphan nuclear receptor TR3/Nur77 inhibits pancreatic cancer cell and tumor growth.
    Lee SO; Abdelrahim M; Yoon K; Chintharlapalli S; Papineni S; Kim K; Wang H; Safe S
    Cancer Res; 2010 Sep; 70(17):6824-36. PubMed ID: 20660371
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 1,1-bis(3'-indolyl)-1-(p-methoxyphenyl)methane activates Nur77-independent proapoptotic responses in colon cancer cells.
    Cho SD; Lei P; Abdelrahim M; Yoon K; Liu S; Guo J; Papineni S; Chintharlapalli S; Safe S
    Mol Carcinog; 2008 Apr; 47(4):252-63. PubMed ID: 17957723
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeting NR4A1 (TR3) in cancer cells and tumors.
    Lee SO; Li X; Khan S; Safe S
    Expert Opin Ther Targets; 2011 Feb; 15(2):195-206. PubMed ID: 21204731
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The orphan nuclear receptor NR4A1 (Nur77) regulates oxidative and endoplasmic reticulum stress in pancreatic cancer cells.
    Lee SO; Jin UH; Kang JH; Kim SB; Guthrie AS; Sreevalsan S; Lee JS; Safe S
    Mol Cancer Res; 2014 Apr; 12(4):527-538. PubMed ID: 24515801
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Nur77 agonists induce proapoptotic genes and responses in colon cancer cells through nuclear receptor-dependent and nuclear receptor-independent pathways.
    Cho SD; Yoon K; Chintharlapalli S; Abdelrahim M; Lei P; Hamilton S; Khan S; Ramaiah SK; Safe S
    Cancer Res; 2007 Jan; 67(2):674-83. PubMed ID: 17234778
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The nuclear receptor TR3 regulates mTORC1 signaling in lung cancer cells expressing wild-type p53.
    Lee SO; Andey T; Jin UH; Kim K; Singh M; Safe S
    Oncogene; 2012 Jul; 31(27):3265-76. PubMed ID: 22081070
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Nuclear receptor 4A1 (NR4A1) as a drug target for treating rhabdomyosarcoma (RMS).
    Lacey A; Hedrick E; Li X; Patel K; Doddapaneni R; Singh M; Safe S
    Oncotarget; 2016 May; 7(21):31257-69. PubMed ID: 27144436
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Potent inhibition of breast cancer by bis-indole-derived nuclear receptor 4A1 (NR4A1) antagonists.
    Hedrick E; Li X; Cheng Y; Lacey A; Mohankumar K; Zarei M; Safe S
    Breast Cancer Res Treat; 2019 Aug; 177(1):29-40. PubMed ID: 31119568
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Nuclear receptor 4A1 as a drug target for breast cancer chemotherapy.
    Hedrick E; Lee SO; Doddapaneni R; Singh M; Safe S
    Endocr Relat Cancer; 2015 Oct; 22(5):831-40. PubMed ID: 26229035
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Activation of Nur77 by selected 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes induces apoptosis through nuclear pathways.
    Chintharlapalli S; Burghardt R; Papineni S; Ramaiah S; Yoon K; Safe S
    J Biol Chem; 2005 Jul; 280(26):24903-14. PubMed ID: 15871945
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The nuclear orphan receptor NR4A1 regulates β1-integrin expression in pancreatic and colon cancer cells and can be targeted by NR4A1 antagonists.
    Hedrick E; Lee SO; Safe S
    Mol Carcinog; 2017 Sep; 56(9):2066-2075. PubMed ID: 28418095
    [TBL] [Abstract][Full Text] [Related]  

  • 14. TR3 modulates platinum resistance in ovarian cancer.
    Wilson AJ; Liu AY; Roland J; Adebayo OB; Fletcher SA; Slaughter JC; Saskowski J; Crispens MA; Jones HW; James S; Fadare O; Khabele D
    Cancer Res; 2013 Aug; 73(15):4758-69. PubMed ID: 23720056
    [TBL] [Abstract][Full Text] [Related]  

  • 15. p21 expression is induced by activation of nuclear nerve growth factor-induced Balpha (Nur77) in pancreatic cancer cells.
    Lee SO; Chintharlapalli S; Liu S; Papineni S; Cho SD; Yoon K; Safe S
    Mol Cancer Res; 2009 Jul; 7(7):1169-78. PubMed ID: 19584258
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 1,1-Bis (3'-indolyl)-1-(p-substitutedphenyl)methane compounds inhibit lung cancer cell and tumor growth in a metastasis model.
    Andey T; Patel A; Jackson T; Safe S; Singh M
    Eur J Pharm Sci; 2013 Oct; 50(2):227-41. PubMed ID: 23892137
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure-dependent activation of endoplasmic reticulum stress-mediated apoptosis in pancreatic cancer by 1,1-bis(3'-indoly)-1-(p-substituted phenyl)methanes.
    Lei P; Abdelrahim M; Cho SD; Liu X; Safe S
    Mol Cancer Ther; 2008 Oct; 7(10):3363-72. PubMed ID: 18852139
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Orphan nuclear receptor TR3/Nur77 biologics inhibit tumor growth by targeting angiogenesis and tumor cells.
    Chen C; Li Y; Hou S; Bourbon PM; Qin L; Zhao K; Ye T; Zhao D; Zeng H
    Microvasc Res; 2020 Mar; 128():103934. PubMed ID: 31654655
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inactivation of the orphan nuclear receptor NR4A1 contributes to apoptosis induction by fangchinoline in pancreatic cancer cells.
    Lee HS; Safe S; Lee SO
    Toxicol Appl Pharmacol; 2017 Oct; 332():32-39. PubMed ID: 28754437
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Diindolylmethane analogs bind NR4A1 and are NR4A1 antagonists in colon cancer cells.
    Lee SO; Li X; Hedrick E; Jin UH; Tjalkens RB; Backos DS; Li L; Zhang Y; Wu Q; Safe S
    Mol Endocrinol; 2014 Oct; 28(10):1729-39. PubMed ID: 25099012
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.