233 related articles for article (PubMed ID: 21368865)
1. Familial amyloid precursor protein mutants cause caspase-6-dependent but amyloid β-peptide-independent neuronal degeneration in primary human neuron cultures.
Sivananthan SN; Lee AW; Goodyer CG; LeBlanc AC
Cell Death Dis; 2010 Nov; 1(11):e100. PubMed ID: 21368865
[TBL] [Abstract][Full Text] [Related]
2. Neuronal NLRP1 inflammasome activation of Caspase-1 coordinately regulates inflammatory interleukin-1-beta production and axonal degeneration-associated Caspase-6 activation.
Kaushal V; Dye R; Pakavathkumar P; Foveau B; Flores J; Hyman B; Ghetti B; Koller BH; LeBlanc AC
Cell Death Differ; 2015 Oct; 22(10):1676-86. PubMed ID: 25744023
[TBL] [Abstract][Full Text] [Related]
3. Activation of Ras-ERK Signaling and GSK-3 by Amyloid Precursor Protein and Amyloid Beta Facilitates Neurodegeneration in Alzheimer's Disease.
Kirouac L; Rajic AJ; Cribbs DH; Padmanabhan J
eNeuro; 2017; 4(2):. PubMed ID: 28374012
[TBL] [Abstract][Full Text] [Related]
4. [Alzheimer disease: cellular and molecular aspects].
Octave JN
Bull Mem Acad R Med Belg; 2005; 160(10-12):445-9; discussion 450-1. PubMed ID: 16768248
[TBL] [Abstract][Full Text] [Related]
5. Increased Caspase-6 activity in the human anterior olfactory nuclei of the olfactory bulb is associated with cognitive impairment.
Foveau B; Albrecht S; Bennett DA; Correa JA; LeBlanc AC
Acta Neuropathol Commun; 2016 Dec; 4(1):127. PubMed ID: 27931265
[TBL] [Abstract][Full Text] [Related]
6. Caspase-6 as a novel early target in the treatment of Alzheimer's disease.
LeBlanc AC
Eur J Neurosci; 2013 Jun; 37(12):2005-18. PubMed ID: 23773070
[TBL] [Abstract][Full Text] [Related]
7. APP transgenic modeling of Alzheimer's disease: mechanisms of neurodegeneration and aberrant neurogenesis.
Crews L; Rockenstein E; Masliah E
Brain Struct Funct; 2010 Mar; 214(2-3):111-26. PubMed ID: 20091183
[TBL] [Abstract][Full Text] [Related]
8. Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models.
Natunen T; Takalo M; Kemppainen S; Leskelä S; Marttinen M; Kurkinen KMA; Pursiheimo JP; Sarajärvi T; Viswanathan J; Gabbouj S; Solje E; Tahvanainen E; Pirttimäki T; Kurki M; Paananen J; Rauramaa T; Miettinen P; Mäkinen P; Leinonen V; Soininen H; Airenne K; Tanzi RE; Tanila H; Haapasalo A; Hiltunen M
Neurobiol Dis; 2016 Jan; 85():187-205. PubMed ID: 26563932
[TBL] [Abstract][Full Text] [Related]
9. APP/Go protein Gβγ-complex signaling mediates Aβ degeneration and cognitive impairment in Alzheimer's disease models.
Bignante EA; Ponce NE; Heredia F; Musso J; Krawczyk MC; Millán J; Pigino GF; Inestrosa NC; Boccia MM; Lorenzo A
Neurobiol Aging; 2018 Apr; 64():44-57. PubMed ID: 29331876
[TBL] [Abstract][Full Text] [Related]
10. The familial Alzheimer's disease APPV717I mutation alters APP processing and Tau expression in iPSC-derived neurons.
Muratore CR; Rice HC; Srikanth P; Callahan DG; Shin T; Benjamin LN; Walsh DM; Selkoe DJ; Young-Pearse TL
Hum Mol Genet; 2014 Jul; 23(13):3523-36. PubMed ID: 24524897
[TBL] [Abstract][Full Text] [Related]
11. Amyloid precursor protein-induced axonopathies are independent of amyloid-beta peptides.
Stokin GB; Almenar-Queralt A; Gunawardena S; Rodrigues EM; Falzone T; Kim J; Lillo C; Mount SL; Roberts EA; McGowan E; Williams DS; Goldstein LS
Hum Mol Genet; 2008 Nov; 17(22):3474-86. PubMed ID: 18694898
[TBL] [Abstract][Full Text] [Related]
12. Therapeutic potential of Nlrp1 inflammasome, Caspase-1, or Caspase-6 against Alzheimer disease cognitive impairment.
Flores J; Noël A; Fillion ML; LeBlanc AC
Cell Death Differ; 2022 Mar; 29(3):657-669. PubMed ID: 34625662
[TBL] [Abstract][Full Text] [Related]
13. Intracellular amyloid precursor protein sorting and amyloid-β secretion are regulated by Src-mediated phosphorylation of Mint2.
Chaufty J; Sullivan SE; Ho A
J Neurosci; 2012 Jul; 32(28):9613-25. PubMed ID: 22787047
[TBL] [Abstract][Full Text] [Related]
14. Alzheimer's disease.
De-Paula VJ; Radanovic M; Diniz BS; Forlenza OV
Subcell Biochem; 2012; 65():329-52. PubMed ID: 23225010
[TBL] [Abstract][Full Text] [Related]
15. DNA synthesis and neuronal apoptosis caused by familial Alzheimer disease mutants of the amyloid precursor protein are mediated by the p21 activated kinase PAK3.
McPhie DL; Coopersmith R; Hines-Peralta A; Chen Y; Ivins KJ; Manly SP; Kozlowski MR; Neve KA; Neve RL
J Neurosci; 2003 Jul; 23(17):6914-27. PubMed ID: 12890786
[TBL] [Abstract][Full Text] [Related]
16. Amyloid β precursor protein as a molecular target for amyloid β--induced neuronal degeneration in Alzheimer's disease.
Bignante EA; Heredia F; Morfini G; Lorenzo A
Neurobiol Aging; 2013 Nov; 34(11):2525-37. PubMed ID: 23714735
[TBL] [Abstract][Full Text] [Related]
17. Evaluation of the Expression of Amyloid Precursor Protein and the Ratio of Secreted Amyloid Beta 42 to Amyloid Beta 40 in SH-SY5Y Cells Stably Transfected with Wild-Type, Single-Mutant and Double-Mutant Forms of the APP Gene for the Study of Alzheimer's Disease Pathology.
Pahrudin Arrozi A; Shukri SNS; Wan Ngah WZ; Mohd Yusof YA; Ahmad Damanhuri MH; Makpol S
Appl Biochem Biotechnol; 2017 Nov; 183(3):853-866. PubMed ID: 28417423
[TBL] [Abstract][Full Text] [Related]
18. Familial Alzheimer's disease mutations at position 22 of the amyloid β-peptide sequence differentially affect synaptic loss, tau phosphorylation and neuronal cell death in an ex vivo system.
Tackenberg C; Kulic L; Nitsch RM
PLoS One; 2020; 15(9):e0239584. PubMed ID: 32966331
[TBL] [Abstract][Full Text] [Related]
19. Soluble Conformers of Aβ and Tau Alter Selective Proteins Governing Axonal Transport.
Sherman MA; LaCroix M; Amar F; Larson ME; Forster C; Aguzzi A; Bennett DA; Ramsden M; Lesné SE
J Neurosci; 2016 Sep; 36(37):9647-58. PubMed ID: 27629715
[TBL] [Abstract][Full Text] [Related]
20. Cross-linking of cell surface amyloid precursor protein leads to increased β-amyloid peptide production in hippocampal neurons: implications for Alzheimer's disease.
Lefort R; Pozueta J; Shelanski M
J Neurosci; 2012 Aug; 32(31):10674-85. PubMed ID: 22855816
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
