205 related articles for article (PubMed ID: 21368874)
1. Cytotoxicity of amyloidogenic immunoglobulin light chains in cell culture.
Sikkink LA; Ramirez-Alvarado M
Cell Death Dis; 2010 Nov; 1(11):e98. PubMed ID: 21368874
[TBL] [Abstract][Full Text] [Related]
2. Role of mutations in the cellular internalization of amyloidogenic light chains into cardiomyocytes.
Levinson RT; Olatoye OO; Randles EG; Howell KG; DiCostanzo AC; Ramirez-Alvarado M
Sci Rep; 2013; 3():1278. PubMed ID: 23417147
[TBL] [Abstract][Full Text] [Related]
3. Amyloid formation in light chain amyloidosis.
Ramirez-Alvarado M
Curr Top Med Chem; 2012; 12(22):2523-33. PubMed ID: 23339305
[TBL] [Abstract][Full Text] [Related]
4. Immunoglobulin light chain amyloid aggregation.
Blancas-Mejia LM; Misra P; Dick CJ; Cooper SA; Redhage KR; Bergman MR; Jordan TL; Maar K; Ramirez-Alvarado M
Chem Commun (Camb); 2018 Sep; 54(76):10664-10674. PubMed ID: 30087961
[TBL] [Abstract][Full Text] [Related]
5. Fatal amyloid formation in a patient's antibody light chain is caused by a single point mutation.
Kazman P; Vielberg MT; Pulido Cendales MD; Hunziger L; Weber B; Hegenbart U; Zacharias M; Köhler R; Schönland S; Groll M; Buchner J
Elife; 2020 Mar; 9():. PubMed ID: 32151314
[TBL] [Abstract][Full Text] [Related]
6. Mutations in specific structural regions of immunoglobulin light chains are associated with free light chain levels in patients with AL amyloidosis.
Poshusta TL; Sikkink LA; Leung N; Clark RJ; Dispenzieri A; Ramirez-Alvarado M
PLoS One; 2009; 4(4):e5169. PubMed ID: 19365555
[TBL] [Abstract][Full Text] [Related]
7. Human amyloidogenic light chains directly impair cardiomyocyte function through an increase in cellular oxidant stress.
Brenner DA; Jain M; Pimentel DR; Wang B; Connors LH; Skinner M; Apstein CS; Liao R
Circ Res; 2004 Apr; 94(8):1008-10. PubMed ID: 15044325
[TBL] [Abstract][Full Text] [Related]
8. Mesenchymal stromal cells protect human cardiomyocytes from amyloid fibril damage.
Lin Y; Marin-Argany M; Dick CJ; Redhage KR; Blancas-Mejia LM; Bulur P; Butler GW; Deeds MC; Madden BJ; Williams A; Wall JS; Dietz A; Ramirez-Alvarado M
Cytotherapy; 2017 Dec; 19(12):1426-1437. PubMed ID: 29037943
[TBL] [Abstract][Full Text] [Related]
9. Dissecting the Molecular Features of Systemic Light Chain (AL) Amyloidosis: Contributions from Proteomics.
Rognoni P; Mazzini G; Caminito S; Palladini G; Lavatelli F
Medicina (Kaunas); 2021 Aug; 57(9):. PubMed ID: 34577839
[TBL] [Abstract][Full Text] [Related]
10. Cell Damage in Light Chain Amyloidosis: FIBRIL INTERNALIZATION, TOXICITY AND CELL-MEDIATED SEEDING.
Marin-Argany M; Lin Y; Misra P; Williams A; Wall JS; Howell KG; Elsbernd LR; McClure M; Ramirez-Alvarado M
J Biol Chem; 2016 Sep; 291(38):19813-25. PubMed ID: 27462073
[TBL] [Abstract][Full Text] [Related]
11. Formation of immunoglobulin light chain amyloid oligomers in primary cutaneous nodular amyloidosis.
Clos AL; Lasagna-Reeves CA; Castillo-Carranza DL; Sengupta U; Jackson GR; Kelly B; Beachkofsky TM; Kayed R
Br J Dermatol; 2011 Dec; 165(6):1349-54. PubMed ID: 21729025
[TBL] [Abstract][Full Text] [Related]
12. Proteotoxicity in cardiac amyloidosis: amyloidogenic light chains affect the levels of intracellular proteins in human heart cells.
Imperlini E; Gnecchi M; Rognoni P; Sabidò E; Ciuffreda MC; Palladini G; Espadas G; Mancuso FM; Bozzola M; Malpasso G; Valentini V; Palladini G; Orrù S; Ferraro G; Milani P; Perlini S; Salvatore F; Merlini G; Lavatelli F
Sci Rep; 2017 Nov; 7(1):15661. PubMed ID: 29142197
[TBL] [Abstract][Full Text] [Related]
13. Tyrosine residues mediate fibril formation in a dynamic light chain dimer interface.
DiCostanzo AC; Thompson JR; Peterson FC; Volkman BF; Ramirez-Alvarado M
J Biol Chem; 2012 Aug; 287(33):27997-8006. PubMed ID: 22740699
[TBL] [Abstract][Full Text] [Related]
14. The Kinetic Stability of a Full-Length Antibody Light Chain Dimer Determines whether Endoproteolysis Can Release Amyloidogenic Variable Domains.
Morgan GJ; Kelly JW
J Mol Biol; 2016 Oct; 428(21):4280-4297. PubMed ID: 27569045
[TBL] [Abstract][Full Text] [Related]
15. Light chain amyloidosis induced inflammatory changes in cardiomyocytes and adipose-derived mesenchymal stromal cells.
Jordan TL; Maar K; Redhage KR; Misra P; Blancas-Mejia LM; Dick CJ; Wall JS; Williams A; Dietz AB; van Wijnen AJ; Lin Y; Ramirez-Alvarado M
Leukemia; 2020 May; 34(5):1383-1393. PubMed ID: 31796914
[TBL] [Abstract][Full Text] [Related]
16. Differential effects on light chain amyloid formation depend on mutations and type of glycosaminoglycans.
Blancas-Mejía LM; Hammernik J; Marin-Argany M; Ramirez-Alvarado M
J Biol Chem; 2015 Feb; 290(8):4953-4965. PubMed ID: 25538238
[TBL] [Abstract][Full Text] [Related]
17. Novel mitochondrial protein interactors of immunoglobulin light chains causing heart amyloidosis.
Lavatelli F; Imperlini E; Orrù S; Rognoni P; Sarnataro D; Palladini G; Malpasso G; Soriano ME; Di Fonzo A; Valentini V; Gnecchi M; Perlini S; Salvatore F; Merlini G
FASEB J; 2015 Nov; 29(11):4614-28. PubMed ID: 26220173
[TBL] [Abstract][Full Text] [Related]
18. In vitro co-expression of human amyloidogenic immunoglobulin light and heavy chain proteins: a relevant cell-based model of AL amyloidosis.
Klimtchuk ES; Prokaeva TB; Spencer BH; Gursky O; Connors LH
Amyloid; 2017 Jun; 24(2):115-122. PubMed ID: 28632419
[TBL] [Abstract][Full Text] [Related]
19. Cu(II) Binding Increases the Soluble Toxicity of Amyloidogenic Light Chains.
Russo R; Romeo M; Schulte T; Maritan M; Oberti L; Barzago MM; Barbiroli A; Pappone C; Anastasia L; Palladini G; Diomede L; Ricagno S
Int J Mol Sci; 2022 Jan; 23(2):. PubMed ID: 35055136
[TBL] [Abstract][Full Text] [Related]
20. Machine learning analyses of antibody somatic mutations predict immunoglobulin light chain toxicity.
Garofalo M; Piccoli L; Romeo M; Barzago MM; Ravasio S; Foglierini M; Matkovic M; Sgrignani J; De Gasparo R; Prunotto M; Varani L; Diomede L; Michielin O; Lanzavecchia A; Cavalli A
Nat Commun; 2021 Jun; 12(1):3532. PubMed ID: 34112780
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
