227 related articles for article (PubMed ID: 21375270)
1. The effect of multiple N-methylation on intestinal permeability of cyclic hexapeptides.
Ovadia O; Greenberg S; Chatterjee J; Laufer B; Opperer F; Kessler H; Gilon C; Hoffman A
Mol Pharm; 2011 Apr; 8(2):479-87. PubMed ID: 21375270
[TBL] [Abstract][Full Text] [Related]
2. Effect of structural and conformation modifications, including backbone cyclization, of hydrophilic hexapeptides on their intestinal permeability and enzymatic stability.
Hess S; Ovadia O; Shalev DE; Senderovich H; Qadri B; Yehezkel T; Salitra Y; Sheynis T; Jelinek R; Gilon C; Hoffman A
J Med Chem; 2007 Nov; 50(24):6201-11. PubMed ID: 17983214
[TBL] [Abstract][Full Text] [Related]
3. cis-Peptide Bonds: A Key for Intestinal Permeability of Peptides? .
Marelli UK; Ovadia O; Frank AO; Chatterjee J; Gilon C; Hoffman A; Kessler H
Chemistry; 2015 Oct; 21(43):15148-52. PubMed ID: 26337831
[TBL] [Abstract][Full Text] [Related]
4. Enhancing Oral Bioavailability of Cyclic RGD Hexa-peptides by the Lipophilic Prodrug Charge Masking Approach: Redirection of Peptide Intestinal Permeability from a Paracellular to Transcellular Pathway.
Schumacher-Klinger A; Fanous J; Merzbach S; Weinmüller M; Reichart F; Räder AFB; Gitlin-Domagalska A; Gilon C; Kessler H; Hoffman A
Mol Pharm; 2018 Aug; 15(8):3468-3477. PubMed ID: 29976060
[TBL] [Abstract][Full Text] [Related]
5. Enantiomeric cyclic peptides with different Caco-2 permeability suggest carrier-mediated transport.
Marelli UK; Bezençon J; Puig E; Ernst B; Kessler H
Chemistry; 2015 May; 21(22):8023-7. PubMed ID: 25917866
[TBL] [Abstract][Full Text] [Related]
6. Intestinal permeability of cyclic peptides: common key backbone motifs identified.
Beck JG; Chatterjee J; Laufer B; Kiran MU; Frank AO; Neubauer S; Ovadia O; Greenberg S; Gilon C; Hoffman A; Kessler H
J Am Chem Soc; 2012 Jul; 134(29):12125-33. PubMed ID: 22737969
[TBL] [Abstract][Full Text] [Related]
7. PAMPA--a drug absorption in vitro model 7. Comparing rat in situ, Caco-2, and PAMPA permeability of fluoroquinolones.
Bermejo M; Avdeef A; Ruiz A; Nalda R; Ruell JA; Tsinman O; González I; Fernández C; Sánchez G; Garrigues TM; Merino V
Eur J Pharm Sci; 2004 Mar; 21(4):429-41. PubMed ID: 14998573
[TBL] [Abstract][Full Text] [Related]
8. Bifunctional peptidomimetic prodrugs of didanosine for improved intestinal permeability and enhanced acidic stability: synthesis, transepithelial transport, chemical stability and pharmacokinetics.
Yan Z; Sun J; Chang Y; Liu Y; Fu Q; Xu Y; Sun Y; Pu X; Zhang Y; Jing Y; Yin S; Zhu M; Wang Y; He Z
Mol Pharm; 2011 Apr; 8(2):319-29. PubMed ID: 21280612
[TBL] [Abstract][Full Text] [Related]
9. Correlation of in vitro and in vivo models for the oral absorption of peptide drugs.
Föger F; Kopf A; Loretz B; Albrecht K; Bernkop-Schnürch A
Amino Acids; 2008 Jun; 35(1):233-41. PubMed ID: 17726639
[TBL] [Abstract][Full Text] [Related]
10. N-methylation of peptides: a new perspective in medicinal chemistry.
Chatterjee J; Gilon C; Hoffman A; Kessler H
Acc Chem Res; 2008 Oct; 41(10):1331-42. PubMed ID: 18636716
[TBL] [Abstract][Full Text] [Related]
11. Modulation of the permeability of H2 receptor antagonists cimetidine and ranitidine by P-glycoprotein in rat intestine and the human colonic cell line Caco-2.
Collett A; Higgs NB; Sims E; Rowland M; Warhurst G
J Pharmacol Exp Ther; 1999 Jan; 288(1):171-8. PubMed ID: 9862768
[TBL] [Abstract][Full Text] [Related]
12. The effect of backbone cyclization on PK/PD properties of bioactive peptide-peptoid hybrids: the melanocortin agonist paradigm.
Ovadia O; Linde Y; Haskell-Luevano C; Dirain ML; Sheynis T; Jelinek R; Gilon C; Hoffman A
Bioorg Med Chem; 2010 Jan; 18(2):580-9. PubMed ID: 20056544
[TBL] [Abstract][Full Text] [Related]
13. Effect of structural modification of α-aminoxy peptides on their intestinal absorption and transport mechanism.
Ma B; Zha H; Li N; Yang D; Lin G
Mol Pharm; 2011 Aug; 8(4):1073-82. PubMed ID: 21630669
[TBL] [Abstract][Full Text] [Related]
14. The angiotensin converting enzyme inhibitory tripeptides Ile-Pro-Pro and Val-Pro-Pro show increasing permeabilities with increasing physiological relevance of absorption models.
Foltz M; Cerstiaens A; van Meensel A; Mols R; van der Pijl PC; Duchateau GS; Augustijns P
Peptides; 2008 Aug; 29(8):1312-20. PubMed ID: 18490081
[TBL] [Abstract][Full Text] [Related]
15. Effects of amino acid chirality and the chemical linker on the cell permeation characteristics of cyclic prodrugs of opioid peptides.
Liederer BM; Fuchs T; Vander Velde D; Siahaan TJ; Borchardt RT
J Med Chem; 2006 Feb; 49(4):1261-70. PubMed ID: 16480263
[TBL] [Abstract][Full Text] [Related]
16. Improvement of enzymatic stability and intestinal permeability of deuterohemin-peptide conjugates by specific multi-site N-methylation.
Dong QG; Zhang Y; Wang MS; Feng J; Zhang HH; Wu YG; Gu TJ; Yu XH; Jiang CL; Chen Y; Li W; Kong W
Amino Acids; 2012 Dec; 43(6):2431-41. PubMed ID: 22674377
[TBL] [Abstract][Full Text] [Related]
17. [Absorption of triterpenoid compounds from Indian bread (Poria cocos) across human intestinal epithelial (Caco-2) cells in vitro].
Zheng Y; Yang XW
Zhongguo Zhong Yao Za Zhi; 2008 Jul; 33(13):1596-601. PubMed ID: 18837324
[TBL] [Abstract][Full Text] [Related]
18. Evaluation of the bile acid transporter in enhancing intestinal permeability to renin-inhibitory peptides.
Kim DC; Harrison AW; Ruwart MJ; Wilkinson KF; Fisher JF; Hidalgo IJ; Borchardt RT
J Drug Target; 1993; 1(4):347-59. PubMed ID: 8069578
[TBL] [Abstract][Full Text] [Related]
19. [Absorption of papaverine, laudanosine and cepharanthine across human intestine by using human Caco-2 cells monolayers model].
Ma L; Yang XW
Yao Xue Xue Bao; 2008 Feb; 43(2):202-7. PubMed ID: 18507350
[TBL] [Abstract][Full Text] [Related]
20. Caco-2 cell permeability and stability of two d-glucopyranuronamide conjugates of thyrotropin-releasing hormone.
Wessling ST; Ross BP; Koda Y; Blanchfield JT; Toth I
Bioorg Med Chem; 2007 Jul; 15(14):4946-50. PubMed ID: 17498958
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]