These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
135 related articles for article (PubMed ID: 21375527)
1. Identification of new cases of early-onset colorectal cancer with an MLH1 epimutation in an ethnically diverse South African cohort. Hitchins MP; Owens SE; Kwok CT; Godsmark G; Algar UF; Ramesar RS Clin Genet; 2011 Nov; 80(5):428-34. PubMed ID: 21375527 [TBL] [Abstract][Full Text] [Related]
2. De novo constitutional MLH1 epimutations confer early-onset colorectal cancer in two new sporadic Lynch syndrome cases, with derivation of the epimutation on the paternal allele in one. Goel A; Nguyen TP; Leung HC; Nagasaka T; Rhees J; Hotchkiss E; Arnold M; Banerji P; Koi M; Kwok CT; Packham D; Lipton L; Boland CR; Ward RL; Hitchins MP Int J Cancer; 2011 Feb; 128(4):869-78. PubMed ID: 20473912 [TBL] [Abstract][Full Text] [Related]
3. Constitutional (germline) MLH1 epimutation as an aetiological mechanism for hereditary non-polyposis colorectal cancer. Hitchins MP; Ward RL J Med Genet; 2009 Dec; 46(12):793-802. PubMed ID: 19564652 [TBL] [Abstract][Full Text] [Related]
4. Evidence of constitutional MLH1 epimutation associated to transgenerational inheritance of cancer susceptibility. Crépin M; Dieu MC; Lejeune S; Escande F; Boidin D; Porchet N; Morin G; Manouvrier S; Mathieu M; Buisine MP Hum Mutat; 2012 Jan; 33(1):180-8. PubMed ID: 21953887 [TBL] [Abstract][Full Text] [Related]
5. Inheritance of epigenetic aberrations (constitutional epimutations) in cancer susceptibility. Hitchins MP Adv Genet; 2010; 70():201-43. PubMed ID: 20920750 [TBL] [Abstract][Full Text] [Related]
6. Concomitant mutation and epimutation of the MLH1 gene in a Lynch syndrome family. Cini G; Carnevali I; Quaia M; Chiaravalli AM; Sala P; Giacomini E; Maestro R; Tibiletti MG; Viel A Carcinogenesis; 2015 Apr; 36(4):452-8. PubMed ID: 25742745 [TBL] [Abstract][Full Text] [Related]
7. Prevalence of MLH1 constitutional epimutations as a cause of Lynch syndrome in unselected versus selected consecutive series of patients with colorectal cancer. Castillejo A; Hernández-Illán E; Rodriguez-Soler M; Pérez-Carbonell L; Egoavil C; Barberá VM; Castillejo MI; Guarinos C; Martínez-de-Dueñas E; Juan MJ; Sánchez-Heras AB; García-Casado Z; Ruiz-Ponte C; Brea-Fernández A; Juárez M; Bujanda L; Clofent J; Llor X; Andreu M; Castells A; Carracedo A; Alenda C; Payá A; Jover R; Soto JL J Med Genet; 2015 Jul; 52(7):498-502. PubMed ID: 25908759 [TBL] [Abstract][Full Text] [Related]
10. MLH1 constitutional and somatic methylation in patients with MLH1 negative tumors fulfilling the revised Bethesda criteria. Crucianelli F; Tricarico R; Turchetti D; Gorelli G; Gensini F; Sestini R; Giunti L; Pedroni M; Ponz de Leon M; Civitelli S; Genuardi M Epigenetics; 2014 Oct; 9(10):1431-8. PubMed ID: 25437057 [TBL] [Abstract][Full Text] [Related]
11. Epigenetic mechanisms in the pathogenesis of Lynch syndrome. Peltomäki P Clin Genet; 2014 May; 85(5):403-12. PubMed ID: 24443998 [TBL] [Abstract][Full Text] [Related]
12. MLH1 germline epimutations in selected patients with early-onset non-polyposis colorectal cancer. Valle L; Carbonell P; Fernandez V; Dotor AM; Sanz M; Benitez J; Urioste M Clin Genet; 2007 Mar; 71(3):232-7. PubMed ID: 17309645 [TBL] [Abstract][Full Text] [Related]
13. MLH1 germline epimutations as a factor in hereditary nonpolyposis colorectal cancer. Hitchins M; Williams R; Cheong K; Halani N; Lin VA; Packham D; Ku S; Buckle A; Hawkins N; Burn J; Gallinger S; Goldblatt J; Kirk J; Tomlinson I; Scott R; Spigelman A; Suter C; Martin D; Suthers G; Ward R Gastroenterology; 2005 Nov; 129(5):1392-9. PubMed ID: 16285940 [TBL] [Abstract][Full Text] [Related]
14. Finding the needle in a haystack: identification of cases of Lynch syndrome with MLH1 epimutation. Hitchins MP Fam Cancer; 2016 Jul; 15(3):413-22. PubMed ID: 26886015 [TBL] [Abstract][Full Text] [Related]
15. Detection of allelic imbalance in MLH1 expression by pyrosequencing serves as a tool for the identification of germline defects in Lynch syndrome. Kwok CT; Ward RL; Hawkins NJ; Hitchins MP Fam Cancer; 2010 Sep; 9(3):345-56. PubMed ID: 20063070 [TBL] [Abstract][Full Text] [Related]
16. Further evidence for heritability of an epimutation in one of 12 cases with MLH1 promoter methylation in blood cells clinically displaying HNPCC. Morak M; Schackert HK; Rahner N; Betz B; Ebert M; Walldorf C; Royer-Pokora B; Schulmann K; von Knebel-Doeberitz M; Dietmaier W; Keller G; Kerker B; Leitner G; Holinski-Feder E Eur J Hum Genet; 2008 Jul; 16(7):804-11. PubMed ID: 18301449 [TBL] [Abstract][Full Text] [Related]
17. Distinction of hereditary nonpolyposis colorectal cancer and sporadic microsatellite-unstable colorectal cancer through quantification of MLH1 methylation by real-time PCR. Bettstetter M; Dechant S; Ruemmele P; Grabowski M; Keller G; Holinski-Feder E; Hartmann A; Hofstaedter F; Dietmaier W Clin Cancer Res; 2007 Jun; 13(11):3221-8. PubMed ID: 17545526 [TBL] [Abstract][Full Text] [Related]
18. The MLH1 c.-27C>A and c.85G>T variants are linked to dominantly inherited MLH1 epimutation and are borne on a European ancestral haplotype. Kwok CT; Vogelaar IP; van Zelst-Stams WA; Mensenkamp AR; Ligtenberg MJ; Rapkins RW; Ward RL; Chun N; Ford JM; Ladabaum U; McKinnon WC; Greenblatt MS; Hitchins MP Eur J Hum Genet; 2014 May; 22(5):617-24. PubMed ID: 24084575 [TBL] [Abstract][Full Text] [Related]
19. Microsatellite instability and novel mismatch repair gene mutations in northern Chinese population with hereditary non-polyposis colorectal cancer. Sheng JQ; Chan TL; Chan YW; Huang JS; Chen JG; Zhang MZ; Guo XL; Mu H; Chan AS; Li SR; Yuen ST; Leung SY Chin J Dig Dis; 2006; 7(4):197-205. PubMed ID: 17054581 [TBL] [Abstract][Full Text] [Related]
20. Lower incidence of colorectal cancer and later age of disease onset in 27 families with pathogenic MSH6 germline mutations compared with families with MLH1 or MSH2 mutations: the German Hereditary Nonpolyposis Colorectal Cancer Consortium. Plaschke J; Engel C; Krüger S; Holinski-Feder E; Pagenstecher C; Mangold E; Moeslein G; Schulmann K; Gebert J; von Knebel Doeberitz M; Rüschoff J; Loeffler M; Schackert HK J Clin Oncol; 2004 Nov; 22(22):4486-94. PubMed ID: 15483016 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]