BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

545 related articles for article (PubMed ID: 21377916)

  • 1. IL-6 signaling in autoimmunity, chronic inflammation and inflammation-associated cancer.
    Neurath MF; Finotto S
    Cytokine Growth Factor Rev; 2011 Apr; 22(2):83-9. PubMed ID: 21377916
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Local blockade of IL-6R signaling induces lung CD4+ T cell apoptosis in a murine model of asthma via regulatory T cells.
    Finotto S; Eigenbrod T; Karwot R; Boross I; Doganci A; Ito H; Nishimoto N; Yoshizaki K; Kishimoto T; Rose-John S; Galle PR; Neurath MF
    Int Immunol; 2007 Jun; 19(6):685-93. PubMed ID: 17496315
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: evidence in crohn disease and experimental colitis in vivo.
    Atreya R; Mudter J; Finotto S; Müllberg J; Jostock T; Wirtz S; Schütz M; Bartsch B; Holtmann M; Becker C; Strand D; Czaja J; Schlaak JF; Lehr HA; Autschbach F; Schürmann G; Nishimoto N; Yoshizaki K; Ito H; Kishimoto T; Galle PR; Rose-John S; Neurath MF
    Nat Med; 2000 May; 6(5):583-8. PubMed ID: 10802717
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Interleukin-6 trans-signalling in chronic inflammation and cancer.
    Scheller J; Ohnesorge N; Rose-John S
    Scand J Immunol; 2006 May; 63(5):321-9. PubMed ID: 16640655
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: role in inflammation and cancer.
    Rose-John S; Scheller J; Elson G; Jones SA
    J Leukoc Biol; 2006 Aug; 80(2):227-36. PubMed ID: 16707558
    [TBL] [Abstract][Full Text] [Related]  

  • 6. IL-6-gp130-STAT3 in T cells directs the development of IL-17+ Th with a minimum effect on that of Treg in the steady state.
    Nishihara M; Ogura H; Ueda N; Tsuruoka M; Kitabayashi C; Tsuji F; Aono H; Ishihara K; Huseby E; Betz UA; Murakami M; Hirano T
    Int Immunol; 2007 Jun; 19(6):695-702. PubMed ID: 17493959
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Interleukin-6 blockade suppresses autoimmune arthritis in mice by the inhibition of inflammatory Th17 responses.
    Fujimoto M; Serada S; Mihara M; Uchiyama Y; Yoshida H; Koike N; Ohsugi Y; Nishikawa T; Ripley B; Kimura A; Kishimoto T; Naka T
    Arthritis Rheum; 2008 Dec; 58(12):3710-9. PubMed ID: 19035481
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Essential roles of IL-6 trans-signaling in colonic epithelial cells, induced by the IL-6/soluble-IL-6 receptor derived from lamina propria macrophages, on the development of colitis-associated premalignant cancer in a murine model.
    Matsumoto S; Hara T; Mitsuyama K; Yamamoto M; Tsuruta O; Sata M; Scheller J; Rose-John S; Kado S; Takada T
    J Immunol; 2010 Feb; 184(3):1543-51. PubMed ID: 20042582
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Targeting interleukin-6 in inflammatory autoimmune diseases and cancers.
    Yao X; Huang J; Zhong H; Shen N; Faggioni R; Fung M; Yao Y
    Pharmacol Ther; 2014 Feb; 141(2):125-39. PubMed ID: 24076269
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The soluble Interleukin 6 receptor: generation and role in inflammation and cancer.
    Chalaris A; Garbers C; Rabe B; Rose-John S; Scheller J
    Eur J Cell Biol; 2011; 90(6-7):484-94. PubMed ID: 21145125
    [TBL] [Abstract][Full Text] [Related]  

  • 11. IL-21 and IL-21R are not required for development of Th17 cells and autoimmunity in vivo.
    Sonderegger I; Kisielow J; Meier R; King C; Kopf M
    Eur J Immunol; 2008 Jul; 38(7):1833-8. PubMed ID: 18546146
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Blockade of interleukin-6 signaling suppresses experimental autoimmune uveoretinitis by the inhibition of inflammatory Th17 responses.
    Hohki S; Ohguro N; Haruta H; Nakai K; Terabe F; Serada S; Fujimoto M; Nomura S; Kawahata H; Kishimoto T; Naka T
    Exp Eye Res; 2010 Aug; 91(2):162-70. PubMed ID: 20420831
    [TBL] [Abstract][Full Text] [Related]  

  • 13. IL-6: regulator of Treg/Th17 balance.
    Kimura A; Kishimoto T
    Eur J Immunol; 2010 Jul; 40(7):1830-5. PubMed ID: 20583029
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Although IL-6 trans-signaling is sufficient to drive local immune responses, classical IL-6 signaling is obligate for the induction of T cell-mediated autoimmunity.
    Lissilaa R; Buatois V; Magistrelli G; Williams AS; Jones GW; Herren S; Shang L; Malinge P; Guilhot F; Chatel L; Hatterer E; Jones SA; Kosco-Vilbois MH; Ferlin WG
    J Immunol; 2010 Nov; 185(9):5512-21. PubMed ID: 20870936
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Protein kinase B/Akt signals impair Th17 differentiation and support natural regulatory T cell function and induced regulatory T cell formation.
    Pierau M; Engelmann S; Reinhold D; Lapp T; Schraven B; Bommhardt UH
    J Immunol; 2009 Nov; 183(10):6124-34. PubMed ID: 19841181
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interleukin-6 trans-signaling in inflammatory bowel disease.
    Mitsuyama K; Sata M; Rose-John S
    Cytokine Growth Factor Rev; 2006 Dec; 17(6):451-61. PubMed ID: 17045835
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Autoimmune inflammation from the Th17 perspective.
    Furuzawa-Carballeda J; Vargas-Rojas MI; Cabral AR
    Autoimmun Rev; 2007 Jan; 6(3):169-75. PubMed ID: 17289553
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Homeostatic (IL-7) and effector (IL-17) cytokines as distinct but complementary target for an optimal therapeutic strategy in inflammatory bowel disease.
    Kanai T; Nemoto Y; Kamada N; Totsuka T; Hisamatsu T; Watanabe M; Hibi T
    Curr Opin Gastroenterol; 2009 Jul; 25(4):306-13. PubMed ID: 19448533
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells.
    Fitzgerald DC; Zhang GX; El-Behi M; Fonseca-Kelly Z; Li H; Yu S; Saris CJ; Gran B; Ciric B; Rostami A
    Nat Immunol; 2007 Dec; 8(12):1372-9. PubMed ID: 17994023
    [TBL] [Abstract][Full Text] [Related]  

  • 20. IL-22 and inflammation: leukin' through a glass onion.
    Zenewicz LA; Flavell RA
    Eur J Immunol; 2008 Dec; 38(12):3265-8. PubMed ID: 19016525
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 28.