BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

235 related articles for article (PubMed ID: 21381897)

  • 1. Effect of interferon-α2b on the expression of various drug-metabolizing enzymes and transporters in co-cultures of freshly prepared human primary hepatocytes.
    Chen C; Han YH; Yang Z; Rodrigues AD
    Xenobiotica; 2011 Jun; 41(6):476-85. PubMed ID: 21381897
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Potential impact of steatosis on cytochrome P450 enzymes of human hepatocytes isolated from fatty liver grafts.
    Donato MT; Lahoz A; Jiménez N; Pérez G; Serralta A; Mir J; Castell JV; Gómez-Lechón MJ
    Drug Metab Dispos; 2006 Sep; 34(9):1556-62. PubMed ID: 16763015
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effects of bergamottin on human and monkey drug-metabolizing enzymes in primary cultured hepatocytes.
    Wen YH; Sahi J; Urda E; Kulkarni S; Rose K; Zheng X; Sinclair JF; Cai H; Strom SC; Kostrubsky VE
    Drug Metab Dispos; 2002 Sep; 30(9):977-84. PubMed ID: 12167562
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differential Effects of Sunitinib on the Expression Profiles of Xenobiotic-Metabolizing Enzymes and Transporters in Rat Liver and Kidneys.
    Korashy HM; Ansari MA; Maayah ZH; Imam F; Raish M; Attafi IM; Alharbi NO; Moraished BA
    Basic Clin Pharmacol Toxicol; 2016 Aug; 119(2):173-83. PubMed ID: 26797788
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effect of honokiol on the induction of drug-metabolizing enzymes in human hepatocytes.
    Cho YY; Jeong HU; Kim JH; Lee HS
    Drug Des Devel Ther; 2014; 8():2137-45. PubMed ID: 25395831
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In vitro investigations into the roles of drug transporters and metabolizing enzymes in the disposition and drug interactions of dolutegravir, a HIV integrase inhibitor.
    Reese MJ; Savina PM; Generaux GT; Tracey H; Humphreys JE; Kanaoka E; Webster LO; Harmon KA; Clarke JD; Polli JW
    Drug Metab Dispos; 2013 Feb; 41(2):353-61. PubMed ID: 23132334
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Proteomic analysis for the impact of hypercholesterolemia on expressions of hepatic drug transporters and metabolizing enzymes.
    Liu Y; Pu QH; Wu MJ; Yu C
    Xenobiotica; 2016 Oct; 46(10):940-7. PubMed ID: 26887802
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Evaluation of 309 molecules as inducers of CYP3A4, CYP2B6, CYP1A2, OATP1B1, OCT1, MDR1, MRP2, MRP3 and BCRP in cryopreserved human hepatocytes in sandwich culture.
    Badolo L; Jensen B; Säll C; Norinder U; Kallunki P; Montanari D
    Xenobiotica; 2015 Feb; 45(2):177-87. PubMed ID: 25183402
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Shikonin upregulates the expression of drug-metabolizing enzymes and drug transporters in primary rat hepatocytes.
    Huang CS; Chen HW; Lin TY; Lin AH; Lii CK
    J Ethnopharmacol; 2018 Apr; 216():18-25. PubMed ID: 29414119
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Efficient assessment of the utility of immortalized Fa2N-4 cells for cytochrome P450 (CYP) induction studies using multiplex quantitative reverse transcriptase-polymerase chain reaction (qRT-PCR) and substrate cassette methodologies.
    Kenny JR; Chen L; McGinnity DF; Grime K; Shakesheff KM; Thomson B; Riley R
    Xenobiotica; 2008 Dec; 38(12):1500-17. PubMed ID: 18989830
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Gene-specific effects of inflammatory cytokines on cytochrome P450 2C, 2B6 and 3A4 mRNA levels in human hepatocytes.
    Aitken AE; Morgan ET
    Drug Metab Dispos; 2007 Sep; 35(9):1687-93. PubMed ID: 17576808
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The potential of Sutherlandia frutescens for herb-drug interaction.
    Fasinu PS; Gutmann H; Schiller H; James AD; Bouic PJ; Rosenkranz B
    Drug Metab Dispos; 2013 Feb; 41(2):488-97. PubMed ID: 23209194
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Disturbed expression of phase I and phase II estrogen-metabolizing enzymes in endometrial cancer: lower levels of CYP1B1 and increased expression of S-COMT.
    Hevir N; Sinkovec J; Rižner TL
    Mol Cell Endocrinol; 2011 Jan; 331(1):158-67. PubMed ID: 20887769
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Colchicine down-regulates cytochrome P450 2B6, 2C8, 2C9, and 3A4 in human hepatocytes by affecting their glucocorticoid receptor-mediated regulation.
    Dvorak Z; Modriansky M; Pichard-Garcia L; Balaguer P; Vilarem MJ; Ulrichová J; Maurel P; Pascussi JM
    Mol Pharmacol; 2003 Jul; 64(1):160-9. PubMed ID: 12815172
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evaluation of P450 inhibition and induction by artemisinin antimalarials in human liver microsomes and primary human hepatocytes.
    Xing J; Kirby BJ; Whittington D; Wan Y; Goodlett DR
    Drug Metab Dispos; 2012 Sep; 40(9):1757-64. PubMed ID: 22679214
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Drug metabolizing enzyme and transporter protein profiles of hepatocytes derived from human embryonic and induced pluripotent stem cells.
    Ulvestad M; Nordell P; Asplund A; Rehnström M; Jacobsson S; Holmgren G; Davidson L; Brolén G; Edsbagge J; Björquist P; Küppers-Munther B; Andersson TB
    Biochem Pharmacol; 2013 Sep; 86(5):691-702. PubMed ID: 23856292
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Substrate-dependent drug-drug interactions between gemfibrozil, fluvastatin and other organic anion-transporting peptide (OATP) substrates on OATP1B1, OATP2B1, and OATP1B3.
    Noé J; Portmann R; Brun ME; Funk C
    Drug Metab Dispos; 2007 Aug; 35(8):1308-14. PubMed ID: 17470528
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effect of silybin and its glycosides on the expression of cytochromes P450 1A2 and 3A4 in primary cultures of human hepatocytes.
    Kosina P; Maurel P; Ulrichová J; Dvorák Z
    J Biochem Mol Toxicol; 2005; 19(3):149-53. PubMed ID: 15977188
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Modular bioreactor for primary human hepatocyte culture: medium flow stimulates expression and activity of detoxification genes.
    Vinci B; Duret C; Klieber S; Gerbal-Chaloin S; Sa-Cunha A; Laporte S; Suc B; Maurel P; Ahluwalia A; Daujat-Chavanieu M
    Biotechnol J; 2011 May; 6(5):554-64. PubMed ID: 21259441
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effect of bupropion on CYP2B6 and CYP3A4 catalytic activity, immunoreactive protein and mRNA levels in primary human hepatocytes: comparison with rifampicin.
    Hesse LM; Sakai Y; Vishnuvardhan D; Li AP; von Moltke LL; Greenblatt DJ
    J Pharm Pharmacol; 2003 Sep; 55(9):1229-39. PubMed ID: 14604466
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.