BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

128 related articles for article (PubMed ID: 21383961)

  • 1. Role of protein kinase C β and vascular endothelial growth factor receptor in malignant pleural mesothelioma: Therapeutic implications and the usefulness of Caenorhabditis elegans model organism.
    Loganathan S; Kanteti R; Siddiqui SS; El-Hashani E; Tretiakova M; Vigneswaran H; Cervantes G; Natarajan V; Husain AN; Vokes EE; Kindler HL; Salgia R
    J Carcinog; 2011 Mar; 10():4. PubMed ID: 21383961
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Protein kinase C beta in malignant pleural mesothelioma.
    Faoro L; Loganathan S; Westerhoff M; Modi R; Husain AN; Tretiakova M; Seiwert T; Kindler HL; Vokes EE; Salgia R
    Anticancer Drugs; 2008 Oct; 19(9):841-8. PubMed ID: 18765998
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Expression and activity of eIF6 trigger malignant pleural mesothelioma growth in vivo.
    Miluzio A; Oliveto S; Pesce E; Mutti L; Murer B; Grosso S; Ricciardi S; Brina D; Biffo S
    Oncotarget; 2015 Nov; 6(35):37471-85. PubMed ID: 26462016
    [TBL] [Abstract][Full Text] [Related]  

  • 4. E7080, a multi-tyrosine kinase inhibitor, suppresses the progression of malignant pleural mesothelioma with different proangiogenic cytokine production profiles.
    Ikuta K; Yano S; Trung VT; Hanibuchi M; Goto H; Li Q; Wang W; Yamada T; Ogino H; Kakiuchi S; Uehara H; Sekido Y; Uenaka T; Nishioka Y; Sone S
    Clin Cancer Res; 2009 Dec; 15(23):7229-37. PubMed ID: 19934291
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Protein kinase C β inhibition by enzastaurin leads to mitotic missegregation and preferential cytotoxicity toward colorectal cancer cells with chromosomal instability (CIN).
    Ouaret D; Larsen AK
    Cell Cycle; 2014; 13(17):2697-706. PubMed ID: 25486357
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Functional Analysis of the Adrenomedullin Pathway in Malignant Pleural Mesothelioma.
    Greillier L; Tounsi A; Berenguer-Daizé C; Dussault N; Delfino C; Benyahia Z; Cayol M; Mabrouk K; Garcia S; Martin PM; Barlesi F; Ouafik L
    J Thorac Oncol; 2016 Jan; 11(1):94-107. PubMed ID: 26762744
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The protein kinase C inhibitor enzastaurin exhibits antitumor activity against uveal melanoma.
    Wu X; Zhu M; Fletcher JA; Giobbie-Hurder A; Hodi FS
    PLoS One; 2012; 7(1):e29622. PubMed ID: 22253748
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Targeting PKC in multiple myeloma: in vitro and in vivo effects of the novel, orally available small-molecule inhibitor enzastaurin (LY317615.HCl).
    Podar K; Raab MS; Zhang J; McMillin D; Breitkreutz I; Tai YT; Lin BK; Munshi N; Hideshima T; Chauhan D; Anderson KC
    Blood; 2007 Feb; 109(4):1669-77. PubMed ID: 17023575
    [TBL] [Abstract][Full Text] [Related]  

  • 9. VEGF and VEGF type C play an important role in angiogenesis and lymphangiogenesis in human malignant mesothelioma tumours.
    Ohta Y; Shridhar V; Bright RK; Kalemkerian GP; Du W; Carbone M; Watanabe Y; Pass HI
    Br J Cancer; 1999 Sep; 81(1):54-61. PubMed ID: 10487612
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Correlations of mRNA expression and in vitro chemosensitivity to enzastaurin in freshly explanted human tumor cells.
    Hanauske AR; Eismann U; Oberschmidt O; Pospisil H; Hanauske-Abel HM; Blatter J; Ma D; Chen V; Lahn M
    Invest New Drugs; 2008 Jun; 26(3):215-22. PubMed ID: 18000644
    [TBL] [Abstract][Full Text] [Related]  

  • 11. KRN633: A selective inhibitor of vascular endothelial growth factor receptor-2 tyrosine kinase that suppresses tumor angiogenesis and growth.
    Nakamura K; Yamamoto A; Kamishohara M; Takahashi K; Taguchi E; Miura T; Kubo K; Shibuya M; Isoe T
    Mol Cancer Ther; 2004 Dec; 3(12):1639-49. PubMed ID: 15634658
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Enzastaurin, a protein kinase C beta inhibitor, suppresses signaling through the ribosomal S6 kinase and bad pathways and induces apoptosis in human gastric cancer cells.
    Lee KW; Kim SG; Kim HP; Kwon E; You J; Choi HJ; Park JH; Kang BC; Im SA; Kim TY; Kim WH; Bang YJ
    Cancer Res; 2008 Mar; 68(6):1916-26. PubMed ID: 18339873
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular mechanism underlying the pharmacological interactions of the protein kinase C-β inhibitor enzastaurin and erlotinib in non-small cell lung cancer cells.
    Steen NV; Potze L; Giovannetti E; Cavazzoni A; Ruijtenbeek R; Rolfo C; Pauwels P; Peters GJ
    Am J Cancer Res; 2017; 7(4):816-830. PubMed ID: 28469955
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeting of the Hedgehog signal transduction pathway suppresses survival of malignant pleural mesothelioma cells in vitro.
    You M; Varona-Santos J; Singh S; Robbins DJ; Savaraj N; Nguyen DM
    J Thorac Cardiovasc Surg; 2014 Jan; 147(1):508-16. PubMed ID: 24094913
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Receptor tyrosine kinase inhibitors and cytotoxic drugs affect pleural mesothelioma cell proliferation: insight into EGFR and ERK1/2 as antitumor targets.
    Barbieri F; Würth R; Favoni RE; Pattarozzi A; Gatti M; Ratto A; Ferrari A; Bajetto A; Florio T
    Biochem Pharmacol; 2011 Nov; 82(10):1467-77. PubMed ID: 21787763
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Development and validation of a drug activity biomarker that shows target inhibition in cancer patients receiving enzastaurin, a novel protein kinase C-beta inhibitor.
    Green LJ; Marder P; Ray C; Cook CA; Jaken S; Musib LC; Herbst RS; Carducci M; Britten CD; Basche M; Eckhardt SG; Thornton D
    Clin Cancer Res; 2006 Jun; 12(11 Pt 1):3408-15. PubMed ID: 16740765
    [TBL] [Abstract][Full Text] [Related]  

  • 17. [Systemic Treatment of Malignant Pleural Mesothelioma].
    Nakano T
    Gan To Kagaku Ryoho; 2017 Dec; 44(13):2041-2047. PubMed ID: 29361614
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The therapeutic efficacy of anti vascular endothelial growth factor antibody, bevacizumab, and pemetrexed against orthotopically implanted human pleural mesothelioma cells in severe combined immunodeficient mice.
    Li Q; Yano S; Ogino H; Wang W; Uehara H; Nishioka Y; Sone S
    Clin Cancer Res; 2007 Oct; 13(19):5918-25. PubMed ID: 17908988
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeting protein kinase C by Enzastaurin restrains proliferation and secretion in human pancreatic endocrine tumors.
    Molè D; Gagliano T; Gentilin E; Tagliati F; Pasquali C; Ambrosio MR; Pansini G; Degli Uberti EC; Zatelli MC
    Endocr Relat Cancer; 2011 Aug; 18(4):439-50. PubMed ID: 21606156
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The oral protein-kinase C beta inhibitor enzastaurin (LY317615) suppresses signalling through the AKT pathway, inhibits proliferation and induces apoptosis in multiple myeloma cell lines.
    Neri A; Marmiroli S; Tassone P; Lombardi L; Nobili L; Verdelli D; Civallero M; Cosenza M; Bertacchini J; Federico M; De Pol A; Deliliers GL; Sacchi S
    Leuk Lymphoma; 2008 Jul; 49(7):1374-83. PubMed ID: 18452078
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.